Pharmaceutical 4024 articles

Beasley Allen has one of the largest and most technologically advanced Mass Torts practices in the country. The Mass Torts division represents numerous people in claims against companies that manufacture and/or market defective pharmaceuticals and/or medical devices. The resources devoted to this division allow the firm to competently and conscientiously handle any group of cases, no matter how large, along with particular catastrophic injury cases.

Our firm was recently involved in one of the greatest victories in Mass Torts history, against drug manufacturer Merck regarding the drug Vioxx. After more than five years of hard-fought and difficult litigation, Merck agreed to pay $4.85 billion, the largest pharmaceutical settlement in U.S. history, to resolve certain Vioxx-related claims involving plaintiffs who suffered a heart attack, including sudden cardiac death, or a stroke.

Long doses of Viagra may help men lose weight, but be at greater risk of side effects


A new Viagra side effect discovered in laboratory rats has researchers testing men to see if the drug can help them lose weight. Researchers discovered that mice that were given Viagra over a long period of time were less likely to become obese even when they were fed fattening foods. Further testing on those mice revealed that the drug caused changes in body fat that translates to calories being used for energy rather than stored as fat. We get fat when we consume more calories than we burn. But how can you burn more fat? It turns out that not ... Read More

Testosterone therapy risks should be carefully weighed

Low T

“I recommend that you think twice before beginning testosterone treatment to make sure it’s appropriate,” Dr. Keith Roach, in his syndicated column “To Your Good Health,” told a 62-year-old man who questioned whether his weekly testosterone injections put him at an increased risk of heart attack and strokes. “Testosterone replacement treatments for me should be given only to men with consistently low testosterone levels and who have symptoms,” said Dr. Roach, a respected physician at Weill Cornell Medical College and New York Presbyterian Hospital. “The most common early symptoms in adult men are low energy levels, poor libido and depressed ... Read More

Several Canadian women sue Bayer over Mirena IUD side effects

mirena IUD

Several Canadian women have filed lawsuits against Bayer alleging the company did not adequately warn that its Mirena intrauterine device could cause serious injuries. The lawsuits mirror concerns of hundreds of other plaintiffs in the United States. In 2013, Health Canada, the country’s drug regulator, received 52 reports of uterine perforations involving the Mirena IUD. Perforations have caused tissue or organ damage. There were also reports that the device migrated from its intended position in the cervix to other parts of the abdomen. Surgery is often required to remove the renegade Mirena IUDs. In some cases women have had to ... Read More

FDA approves long-acting testosterone with black box warning

Low T

A new long-acting testosterone therapy has been approved by the Food and Drug Administration (FDA), but the approval comes with a black box warning and strong prescribing restrictions. Aveed, made by Endo Pharmaceuticals, is a long-acting depot formulation of testosterone in caster oil and benzyl benzoate. It is administered in a single 3-mL (750 mg) intramuscular injection given once at initiation of therapy, at four weeks after initiation of treatment, and then every 10 weeks thereafter. Aveed is approved to treat hypogonadism, a condition in which men produce too little of the hormone due to disease or defect. The FDA required ... Read More

Docu-Series details Risperdal makers’ failure to warn


“Austin has a deformity. He has female breasts,” said an attorney for the family of an autistic man suing Johnson & Johnson and its subsidiary Janssen Pharmaceuticals. “They are, I think, what we could describe as large, pendulous breasts, not some small, little thing, but significant, for a male, deformity.” Austin Pledger, now 20, was a child when his doctors prescribed the antipsychotic drug Risperdal to treat symptoms associated with autism. The family filed a lawsuit against the drug’s maker alleging they failed to warn Austin’s doctors that Risperdal was dangerous when taken by children, and that failure caused Austin to ... Read More

Researchers eye diabetes drugs as possible alcohol addition treatment


A class of type 2 diabetes drugs, which includes the brand names Victoza and Byetta, may help curb alcohol addiction and could pave the way for wider usage of the medications, according to a new study. However, it could also expose more people to potentially deadly side effects. Victoza and Byetta are in a class of drugs known as GLP-1 agonists. They work by mimicking the functions of the natural incretin hormones in the body that help lower post-meal blood sugar levels. These functions include stimulating the release of insulin by the pancreas after eating, inhibiting the release of glucagon ... Read More

Doctors waiting on real-world safety data from new blood thinners


Drugs from a new class of blood thinners are gaining traction in sales, but analysts say they have a lot to prove before doctors push aside the long-used warfarin for the new drugs. The new blood thinners are from a class known as factor Xa inhibitors and include the brand names Pradaxa, Xarelto and Eliquis. They have been approved sometime within the past five years and are used to prevent strokes caused by blood clots in patients with a common heart rhythm abnormality called atrial fibrillation. Xarelto and Eliquis are also used to treat and prevent blood clots in various ... Read More

Europe approves novel cholesterol-lowering drug Praluent


European drug regulators have approved Regeneron Pharmaceuticals and Sanofi’s novel new non-statin, cholesterol-lowering medication, Praluent. The drug, known as a PCSK9 inhibitor, can be used alone or in combination with statins or other lipid-lowering therapies in patients with high LDL cholesterol. The U.S. Food and Drug Administration (FDA) approved Praluent in July, and a second PCSK9 inhibitor, Repatha made by Amgen, a month later. Repatha was approved by the European Commission in July. PCSK9 inhibitors work by targeting and suppressing a particular gene involved in the regulation of how much cholesterol the liver filters out. The drugs are designed as ... Read More

Mammogram technology found useless in new study

Breast Cancer Awareness Ribbon

Computer-aided technology by Hologic Inc. and Icad Inc., used in 90 percent of mammograms performed in the United States for breast cancer screenings, failed to find more tumors than mammograms without the computerized assistance, a new study has found. “There is absolutely no question from our research that computer-aided detection offers no benefit to catching cancers that otherwise would have been missed or improving performance,” said Constance Lehman, the study’s lead researcher and director of breast imaging and co-director of the Avon Foundation Comprehensive Breast Evaluation Center at Massachusetts General Hospital in Boston. “We should certainly stop charging for it. ... Read More

Saxenda diet drug may increase risk of Victoza side effects

bathroom scale

Novo Nordisk has seen success with its type 2 diabetes drug Victoza. But a different indication for the medication, which sprang from a Victoza side effect, may prove to be even more profitable for the drug company. Victoza, which contains the drug ingredient liraglutide, is a once-daily injection to treat Type 2 diabetes. It was approved by the Food and Drug Administration (FDA) in January 2010. It is in the same drug class as the diabetes medications Byetta and Januvia. One side effect from these medications is weight loss, which prompted Novo Nordisk to begin testing the drug in higher doses ... Read More