Pharmaceutical

Study: Depressed diabetics at increased risk for heart attack

depression Study: Depressed diabetics at increased risk for heart attackType 2 diabetics who are depressed are at higher risk of having a heart attack compared to people who have neither condition, according to researcher reported at the European Association for the Study of Diabetes.

People who have diabetes or who suffer from depression also have an elevated risk – although to a lesser extent than people with both conditions – of having a heart attack, researchers found. The greatest risk was among individuals between the ages of 45 and 65, and the strongest association was among women.

The study involved data from more than 3.7 million people ages 45 to 84 obtained from Swedish national registries of prescription drug use, hospitalizations, and deaths. The analysis did not include individuals who had a heart attack before the study period. Prescriptions for diabetes and depression medications were used as surrogates for the conditions.

Researchers note that the study was published as an abstract and the data and conclusions should only be considered preliminary until they are published in a peer-reviewed journal.

The study does beg the question whether the increased risk of heart attack among diabetics and depressed patients may be connected to the medications they were taking.

For example, in 2010, the Food and Drug Administration(FDA) severely restricted the use of the type 2 diabetes drug Avandia after the drug was linked to fatal heart attacks. Diabetes medications have also been associated with other serious health problems. In 2011, the FDA warned that studies showed Actos put users at risk for bladder cancer. More recent studies suggest that the diabetes drugs Januvia and Byetta can cause acute pancreatitis and pancreatic cancer.

Source: MedPage Today