The artificial sweetener sucralose, found in the brand-name sugar substitute Splenda, has been linked to an increased risk of leukemia, according to a study published in the January issue of the International Journal of Occupational and Environmental Health.
Italian researchers found “significant dose-related increased incidence of males bearing malignant tumors” and a “significant dose-related increased incident of hematopoietic neoplasias in males” after being fed high amounts of sucralose.
Splenda is manufactured by British company Tate & Lyle and America’s Johnson & Johnson. Sucralose-based Splenda products are developed in partnership with Johnson & Johnson’s subsidiary McNeil Nutritionals LLC. The product was introduced in the United States in 1999 and has since overtaken Equal in the $1.5 billion artificial sweetener market. Studies conducted by the manufacturers of Splenda claim the sugar substitute is safe.
“More studies are necessary to show the safety of sucralose, including new and more adequate carcinogenic bioassay on rats. Considering that millions of people are likely exposed, follow-up studies are urgent,” the researchers said.
Sucralose is made by chemically reacting sugar (sucrose) with chlorine. It is currently used in more than 4,500 products, according to the Center for Science in the Public Interest.
Source: Fox 5