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acid reflux 20 articles

Vials of injectable sleep drug Propofol recalled

Hospira is recalling seven lots of Propofol Injectable Emulsion, an anesthetic used to put people to sleep before and during surgeries, due to visible metal particles floating in glass vials of the solution. This can result in health issues. For example, injected particle matter may result in local inflammation, phlebitis, and/or low level allergic response through mechanical disruption of tissue or immune response to the particulate. Capillaries, which may be as small as the size of a red blood cell, may become occluded. Chronically, following sequestration, particulate matter may lead to the formation of granulomas, most likely in the lungs. ... Read More

Study looks at safety of Reglan as treatment for morning sickness

The acid reflux drug metoclopramide may be a safe and effective morning sickness treatment for pregnant women, a new study suggest. Metoclopramide, also known by the brand name Reglan, is used to treat esophageal reflux disease (GERD), nausea, vomiting and diabetic gastroparesis, a condition in which the stomach digests food too slowly. Researchers looked at data from more than 40,000 women who were given metoclopramide while pregnant and found they were no more likely to have a miscarriage or have a baby with birth defects than women who did not take the drug. About half of all pregnant women experience nausea ... Read More

Recall is just the latest in string of manufacturing mishaps for Hospira

Drug maker Hospira Inc.’s announced this week that it was recalling some injectable drugs because glass strands were found the vials, and if used could cause a host of complications from minor vein inflammation to serious organ failure. The recall is one of nearly a half-dozen manufacturing mishaps involving the company’s products so far this year. This week’s recall involved metoclopramide (Reglan), used to treat severe acid reflux, and ondansetron (Zofran), used to prevent nausea and vomiting in cancer patients. The drugs were distributed nationwide to wholesalers, hospitals and pharmacies from June to September. Hospira blamed the issue on its glass ... Read More

Injectable Reglan, Zofran recalled due to hazardous vial defect

Some injectable medications used to treat severe acid reflux and other gastrointestinal conditions are being recalled because tiny strands of glass were found in some vials. If the glass comes loose and is injected in to patients, it could cause serious and potentially life threatening consequences. The nationwide recall involves one lot of metoclopramide injection and two lots of ondansetron injection. Metocloparmide is known by the brand name Reglan and is used to treat gastric esophageal reflux disease (GERD), and a heartburn condition known as gastroparesis in diabetics. Ondansetron, known by the brand names Zofran and Zuplenz, prevents nausea and vomiting ... Read More

Long-term PPI use linked to low serum magnesium levels

The Food and Drug Administration (FDA) is notifying doctors that long-term use of heartburn medications known as proton pump inhibitors, or PPIs, may cause low serum magnesium levels, a condition known as hypomagnesaemia, which can lead to potentially serious health problems such as muscle spasms, irregular heartbeats, and convulsions. The condition is most often seen in patients who have used PPIs for more than a year. PPIs are used to treat acid reflux, heartburn and other gastrointestinal conditions such as gastroesophageal reflux disease (GERD), stomach and small intestine ulcers, and inflammation of the esophagus. They work by reducing the amount ... Read More

Metozolv label has new tardive dyskinesia warning

The new chewable heartburn medication Metozolv, an orally disintegrating version of Reglan (metoclopramide), has added a warning to its label alerting users of a risk of the serious movement disorder Tardive Dyskinesia with long-term use of the drug. The change to the drug’s safety label was approved by the Food and Drug Administration (FDA) and announced this month. The updated information to the drug’s WARNINGS section reinforces the Boxed Warning that was added to all metoclopramide-containing drugs in June 2009. The new warning states, “Treatment with metoclopramide can cause Tardive Dyskinesia (TD), a potentially irreversible and disfiguring disorder characterized by ... Read More

Restless leg syndrome turns out to be movement disorder caused by Reglan

PHOENIX, ARIZONA – Ron, a musician and artist, was having trouble sleeping. His legs would move involuntarily back and forth under the sheets. At first, both Ron and his doctors thought he suffered from restless leg syndrome. But after a battery of tests conducted by neurologists, and a review of his medical history and medications, doctors determined that Ron suffered from a Parkinson’s-like condition known as Tardive Dyskinesia. They say it was caused by the heartburn medication Reglan. Reglan, also known by the generic metoclopramide, is a prescription medication used to treat severe heartburn, acid reflux, gastroparesis and other gastrointestinal ... Read More

Long-term use of heartburn drug can cause serious movement disorder

Thousands of people who suffer from gastrointestinal problems such as severe heartburn, acid reflux and gastroparesis, are treated with the prescription drug Reglan, known by the generic metoclopramide. These drugs were originally prescribed for daily use for as long as two years in some patients. What patients may not realize is that long-term use of the drug is no longer recommended – and, in fact, falls under an FDA black box warning – as it can cause a serious and sometimes permanent neurological disorder known as Tardive Dyskinesia. Tardive Dyskinesia is an involuntary movement disorder that causes repetitive movements of ... Read More

Infant reflux: Natural remedies should be tried before medical ones

All babies spit up on occasion. It usually occurs because the sphincter at the top of the stomach is often loose, causing babies to spit milk out of their mouths or noses. In otherwise healthy babies who are growing well, the contents of this spit up is mostly milk and parents shouldn’t worry. But for some babies, the spit up contains stomach acid, which can make the lining of the baby’s esophagus tender, red and swollen. This reflux of acid can also be inhaled into the lungs, irritating the sensitive linings. These babies may respond to the bottle or breast ... Read More

Drugs that block dopamine receptors can cause Tardive Dyskinesia

An estimated 250,000 to 400,000 people in the United States have Tardive Dyskinesia, a disfiguring and debilitating involuntary movement disorder involving symptoms such as lip smacking, tongue thrusting and protruding, eye blinking and bulging, head jerking, facial grimacing, and puckering and pulsing of the lips. The muscle spasms can become painful and embarrassing and often are permanent. But what is most disturbing is that in many cases, the condition could have been prevented. Tardive Dyskinesia is caused by the long-term use of drugs that block dopamine receptors known as dopamine-receptors antagonists or DRAs. Most of the drugs in this category ... Read More