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aggressive 9 articles

Erectile dysfunction drug Strenda given new ‘fast acting’ status by FDA

Auxillium and Vivus’ erectile dysfunction drug Strenda has been granted a new designation by the Food and Drug Administration (FDA) that may help it compete against the dominating pills in the market, Pfizer’s Viagra and Eli Lilly’s Cialis. Strenda has been granted “fast-acting” status, allowing the pill to be taken just 15 minutes before sex, instead of 30 minutes as previously stated on its label. Comparatively, Cialis must be taken daily while Viagra must be taken one to two hours before sex. Strendra contains the active ingredient avanafil, which is in a class of drugs called phosphodiesterase inhibitors. Other drugs in ... Read More

Family says defective metal-on-metal hip implant caused mother’s brain cancer

A woman who had filed a lawsuit against Johnson & Johnson for its defective metal-on-metal hip implant has died of an aggressive brain cancer, a disease her family believes was caused by blood poisoning from her corroding artificial hip. Bharucha had broken a hip when she suffered a fall and in 2007 was fitted with Johnson & Johnson’s DePuy ASR hip replacement system. The surgery did not relieve her pain or help her regain her mobility. In fact, she grew increasingly worse. By 2011, a year after the device was recalled due to premature failures, Bharucha had revision surgery to ... Read More

Antioxidant vitamin supplements may speed lung cancer growth

Taking vitamin supplements is thought to help ward off health problems like cancer, but a new study shows they may actually worsen conditions in some people. Swedish researchers gave antioxidants to laboratory mice with early-stage lung cancer. Rather than staving off the cancerous growths in mice, the supplements caused the tumors to multiply and become so aggressive that the animals died twice as fast as the mice that did not receive the supplements. The researchers theorized that the extra vitamins actually blocked one of the body’s key cancer-fighting mechanisms. General health recommendations cannot be based on animal studies, researchers pointed ... Read More

Experimental vaccine shows promise against most aggressive brain tumors

More than 90 percent of patients with a highly reoccurring type of brain cancer treated with an experimental vaccine were alive six months after undergoing surgery, a far better prognosis than patients who followed standard treatment, according to a study published in the journal Neuro-Oncology and accompanied by an editorial highlighting the importance of the trial.  “The grim prognosis is exactly why new research is important,” says Orin Bloch, MD, a neurosurgeon at Northwestern Memorial Hospital and lead author of the study. The tumor, known as glioblastoma multiforme, or GBM, is the same type of tumor that took the life ... Read More

FDA approves new type of breast cancer treatment

The Food and Drug Administration (FDA) has approved a first-of-a-kind breast cancer cocktail designed to kill tumor cells while sparing healthy ones. The new drug, Kadcyla, made by Roche, contains Herceptin, an established breast cancer treatment, with a powerful chemotherapy drug, and a third chemical that binds the two medicines together. Researchers say the Kadcyla may be more beneficial for some breast cancer patients because it delivers more medicine and has fewer side effects. Kadcyla is indicated for patients with HER2-positive breast cancer, an aggressive form of the disease that generally does not respond well to hormone therapy. About 20 ... Read More

Aggressive approach needed to prevent diabetes in pre-diabetics

An earlier and more aggressive approach is needed in people at risk for developing type 2 diabetes in order to reduce the escalating number of people diagnosed with the disease each year, according to a study published in the Lancet. Type 2 diabetes is on the rise worldwide and unhealthy diets and sedentary lifestyles are to blame. People in the early stages of diabetes, known as pre-diabetes, who ignore important warning signs, such as elevated blood sugar, will most likely go on to develop the condition. Once someone develops type 2 diabetes, it is almost impossible to fully recover. However, ... Read More

FDA approves new breast cancer fighting drug

A new drug has been approved by the Food and Drug Administration (FDA) to aid in the fight against breast cancer. Perjeta (pertuzumab), made by Genentech, was approved in combination with Herceptin (trastuzumab) and docetaxel chemotherapy for the treatment of HER2-positive metastatic breast cancer in people who have not received prior anti-HER2 therapy or chemotherapy for metastatic breast cancer. HER2-positive breast cancer is a breast cancer that tests positive for a protein called human epidermal growth factor receptor 2, which promotes the growth of cancer cells. In about 1 of every 5 breast cancers, the cancer cells make an excess ... Read More

Patients with aggressive breast cancer granted experimental drugs

Women with highly aggressive, early-stage breast cancers will now be able to try experimental drugs before they have been tested for safety and efficacy in the sickest cancer patients. The new guideline is part of a new push by the Food and Drug Administration (FDA) to speed lifesaving drugs to patients faster. Previous practice was to test cancer drugs on the sickest patients with end-stage disease. If the drug appeared to extend life and slow the progression of the disease, it was then approved for use in patients in earlier stages of breast cancer. But it could take nearly a ... Read More

Study finds HRT breast cancers are more likely to be advanced, deadly

The evidence weighing the benefits and risks of hormone replacement therapy (HRT) in menopausal and postmenopausal women continues to tip toward the same conclusion – that taking HRT is dangerous. HRT was once heralded as a cure-all for problematic symptoms of menopause, including hot flashes, sleeping difficulties, mood swings and vaginal dryness. It was also given the added benefit of protecting women against heart disease and osteoporosis. However, opinion quickly changed in 2002, after a large study of postmenopausal women found that HRT that combined the hormones estrogen and progesterone increased a woman’s risk for breast cancer by about one extra ... Read More