Tagged Articles

Alzheimer’s disease 38 articles

Fall risk, fractures more likely among elderly patients using antidepressants

Elderly patients treated with antidepressants to treat symptoms of Alzheimer’s disease have nearly double the risk of having a hip fracture, and the risk remains high even four years after the initiation of therapy, according to a new study from the University of Eastern Finland. Hip fractures are a serious injury that can be life threatening. They are even more dangerous – and prevalent – in the elderly. Multiple medications, poor vision and balance problems make older individuals more apt to trip and fall. And falls more often lead to fractures, particularly in the hip, of the elderly because their bones tend to weaken ... Read More

Study Links Consumption of Diacetyl with Alzheimer’s Disease

Talk of diacetyl has risen in recent years, especially after eight workers at a popcorn plant were diagnosed with bronchiolitis obliterans after prolonged exposure in the early 2000s. For this reason, the disease is also referred to as “popcorn lung“. Bronchiolitis obliterans is a serious lung disease in which the smallest airways of the lungs become permanently blocked by excess scar tissue. It is often misdiagnosed as asthma, bronchitis, emphysema or even pneumonia because the symptoms are similar, with the patient experiencing a persistent cough, wheezing, shortness of breath and fatigue. The only treatment for bronchiolitis obliterans is a lung transplant. Diacetyl (DA) is used for artificial ... Read More

Study links commonly prescribed anti-anxiety, insomnia drugs to Alzheimer’s in elderly

Older people who used drugs known as benzodiazepines to relieve anxiety and help them sleep are more likely to develop Alzheimer’s disease, and those who use the drugs frequently and in higher doses are at even greater risk, a new study has found. Benzodiazepines, which include the brand names Xanax, Valium, Ativan and Klonopin, are commonly prescribed to treat insomnia, agitation and anxiety – early symptoms of Alzheimer’s disease in the elderly. But do these medications permit, cause, or even hasten the onset of Alzheimer’s disease? To investigate this issue further, researchers compared benzodiazepine use among nearly 1,800 elderly patients ... Read More

Pharmacy group wants black box warning added to antibiotic Levaquin

A University of South Carolina pharmacy group is petitioning the Food and Drug Administration (FDA) to put the strongest warning possible on Johnson & Johnson’s antibiotic Levaquin alerting consumers about the potential for cellular damage that could lead to serious diseases. The Southern Network on Adverse Reactions, a project of the South Carolina College of Pharmacy, says the public should be aware that the antibiotic commonly prescribed to treat infections can damage mitochondria that reside in the cells, resulting in mitochondrial toxicity, which is associated with Alzheimer’s disease, Parkinson’s disease, Lou Gehrig’s disease, and liver damage. Levaquin, also known as levofloxacin, ... Read More

Controversial analysis suggests Actos may help protect users from dementia

The type 2 diabetes drug Actos could help ward off dementia, a new analysis has found. However, researcher say more analysis is needed as well as adverse side effects addressed before the medication can be recommended as a preventative measure. The analysis involved data from Germany’s biggest public health insurer, which included about 146,000 patients aged 60 or older. The patients were tracked from 2004 to 2010, during which time about 14,000 of them developed dementia. When prescriptions for Actos were factored into the analysis, researchers found that patients taking Actos had about a 6 percent decline in the likelihood ... Read More

New study raises questions about safety of testosterone replacement therapy

A new study raises questions about the link between testosterone replacement therapy and heart attacks. Researchers at the University of Texas, Medical Branch at Galveston, studied more than 25,000 men, all Medicare beneficiaries older than 65 who were treated with testosterone injections for up to eight years. These men were compared to about 19,000 men of the same age who did not use testosterone treatments. Researchers found that testosterone users were not at greater risk of having a heart attack compared to nonusers of testosterone therapy. Researchers did not track strokes, blood clots, dementia or death. The results contradict several ... Read More

Experimental vaccine helps extend life of brain cancer patients

An experimental cancer vaccine helped patients with one of the most common malignant brain tumors live almost twice as long as patients who received the standard treatment of care. Glioblastoma multiforme, or GMB, is one of the most aggressive malignant brain tumors. The tumors arise from astrocytes, star-shaped cells that make up the supportive tissue of the brain. They are highly malignant because the cells reproduce quickly and are supported by a large network of blood vessels. GMB is the same tumor that affected the late Sen. Ted Kennedy. Most people with a GMB die within one year of diagnosis ... Read More

Study links testosterone therapy to brain damage

Testosterone replacement therapy may cause brain damage in Caucasian men, a new study suggests, adding yet another strike against the increasingly popular hormone treatment. Testosterone treatments are approved to boost levels of the hormone in men experiencing symptoms of so-called Low-T, such as a diminished sex drive, fatigue, weight gain and muscle loss. In recent years, prescriptions for testosterone supplements have skyrocketed in the United States, leading many experts to worry that the drug is being given to men who don’t necessarily need it. In its natural form, testosterone helps protect the brain against free radicals, which can damage brain ... Read More

Type 2 diabetes may shrink brain tissue, lead to cognitive disorders

Long-term type 2 diabetes may shrink gray matter, the portion of the brain responsible for memory, emotions, decision-making and self control, according to a new study published in the journal Radiology. For each decade a person has diabetes, his brain looks about two years older than a non-diabetic, researchers found. For the study, researchers with the University of Pennsylvania analyzed MRI scans to evaluate brain structure of more than 600 patients with type 2 diabetes. They were surprised to find that diabetes was not linked to just the damaging effect of the tiny blood vessels in the brain, but by ... Read More

Judge refuses to approve NFL’s multimillion dollar concussion settlement for retired players

A Pennsylvania federal judge has refused to approve a $760 million multidistrict litigation settlement agreement between the National Football League (NFL) and former players who sustained long-term injuries from concussions. U.S. District Judge Anita Brody said she was concerned that the league wasn’t putting up enough money to compensate all members in the class. The settlement is designed to resolve lawsuits from retired NFL players who alleged that the league did not do enough to protect players from concussions and other brain trauma nor did they do enough to address the long term risks of these injuries. The arrangement is designed ... Read More