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Ambien 11 articles

Ambien in high cumulative doses linked to Alzheimer’s in elderly

High cumulative doses of the sleep aid Ambien have been linked to Alzheimer’s disease in elderly individuals, according to a retrospective study published in the Journal of the American Geriatric Society. Ambien contains the active ingredient zolpidem, which is also found in the brand name sleep aids Intermezzo, Edluar and Zolpimist. It is a prescription medication used to treat insomnia. The study involved the evaluation of nearly 7,000 patients 65 and older who had never been diagnosed with Alzheimer’s disease. Half were prescribed zolpidem and the other half were not. Among the group taking zolpidem, 71 percent were taking what ... Read More

Man says cough med made him kill wife in his sleep

A young man studying to be a pastor called 911 in the early hours of Labor Day weekend claiming he stabbed his wife of five months while asleep, blaming the incident on a higher than indicated dose of over-the-counter Coricidin Cold & Cough medicine. “I know it can make you feel good and sometimes I can’t sleep at night,” Matthew James Phelps told the 911 dispatcher. Phelps, 29, says he woke from a dream and turned on the lights of his bedroom only to find his wife, Lauren Ashley-Nicole Phelps, also 29, stabbed and unresponsive in their Raleigh, North Carolina ... Read More

FDA requires stronger next-day psychomotor impairment warnings on Ambien sleeping pills

The safety labels of the prescription sleep aids Ambien and Ambien CR have been updated to strengthen warnings regarding next-day psychomotor impairment, such as impaired driving, if the drugs are taken with less than a full night’s sleep, if a higher than recommended dose is taken, if the medication is taken with other central nervous system depressants or alcohol, or if they are taken with drugs that may alter the levels of the active ingredient in the blood. The safety labels for Ambien and Ambien CR, which contain the active ingredient zolpidem, will now state that vehicle drivers and machine operators should ... Read More

New Ambien safety label warns of severe injury risk

The safety label for the prescription sleep aid Ambien (zolpidem tartrate) has been updated to include a new warning for severe injuries, the Food and Drug Administration (FDA) announced. “Zolpidem can cause drowsiness and a decreased level of consciousness, which may lead to falls and consequently to severe injuries,” the new warning states. “Severe injuries such as hip fractures and intracranial hemorrhage have been reported.” A 2012 study linked the commonly prescribed sleeping pill to a greatly increased risk of falls in hospital patients. The Mayo Clinic study of more than 16,000 hospitalized patients found that the fall rate among ... Read More

New sleeping pill gets FDA approval, awaits DEA clearance

A new type of prescription sleep aid has won approval from the Food and Drug Administration (FDA) and if given clearance from the Drug Enforcement Administration (DEA) should be commercially available later this year. Belsomra, made by Merck & Co., works by temporarily blocking chemicals in the brain that control sleep cycle and keep people awake at night. The sleeping pill is designed to help people with insomnia to sleep through the night. Belsomra was approved based on trials that pitted the medication against a placebo. It was not tested against other sleep aids, however, so it is not known ... Read More

FDA warns of next-day impairment with sleep aid Lunesta

The insomnia drug Lunesta (eszopiclone) can linger in users’ bloodstreams hours longer than intended, causing impairment of driving and other activities that require alertness, the Food and Drug Administration warned. The agency is recommending that starting doses be lowered to 1 mg at bedtime for both men and women. The drug labels for Lunesta and its generic counterparts will be updated to reflect the new warnings and recommended dosing. The new dosing is based on a study that found that the previously recommended dose of 3 mg can cause impairment of driving skills, memory and coordination that can last more ... Read More

Sleeping pills land more people in emergency room than ever before

The popular prescription sleep medication Ambien and others that contain the active ingredient zolpidem are sending an increasing number of people to the emergency room, a new study has found. Researchers with the U.S. Substance Abuse and Mental Health Administration (SAMHSA) pored through data from a public health surveillance system and found a near 220 percent increase from 2005 to 2010 in emergency room visits involving side effects related to these sleep aids. Zolpidem-containing drugs include the brand names Ambien, Ambien CR, Intermezzo, Stilnox and Sublinox, as well as generic versions. The medication is used to treat insomnia and, in some ... Read More

Sleep aid may increase risk of hip fracture in nursing home patients

Sleep aids are commonly given to nursing home patients to help them rest, but a new study shows that a popular type prescription sleeping pill might put patients at increased risk for hip fractures. Researchers at Harvard Medical School in Boston reviewed data from more than 15,500 nursing home residents who experienced a hip fracture between July 2007 and December 2008. About 1,700 of them were given a nonbenzodiazepine hypnotic sleep aid before their hip fracture. These drugs include the brand names Lunesta, Sonata, Ambien and Intermezzo. Researchers determined that patients who took these drugs were two-thirds more likely to experience a ... Read More

FDA requires lower recommended dosage for insomnia drug Ambien

Many people who take the prescription sleep aid Ambien at bedtime still have high levels of the drug in their systems the morning after, which affects their alertness and impairs their ability to drive vehicles, the Food and Drug Administration (FDA) announced this week. The agency is requiring that the recommended dosage be lowered to reduce this risk. Ambien and Ambien CR, which contain the active ingredient zolpidem, are sold both in brand name and in generic versions. Zolpidem is also the drug used in the sleep aids Ediuar, Zolpimist and Intermezzo. The FDA issued a safety communication that also ... Read More

FDA approves new prescription sleeping pill

Insomniacs now have a new prescription sleep aid option. After several rejections based on safety issues, Food and Drug Administration (FDA) has finally approved Intermezzo, a lower dose version of the prescription sleeping pill Ambien, for people who wake in the middle of the night and have trouble falling back to sleep. Intermezzo (zolpidem tartrate siblingual tablets) was approved based on two clinical trails involving more than 370 patients, which found that patients who took the drug fell back to sleep faster than those who took a placebo. The most common side effects were headache, nausea and fatigue. The recommended ... Read More