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antibiotics 80 articles

Oral antibiotics linked to kidney stones

Children and adults treated with some oral antibiotics have a significantly higher risk of developing kidney stones, with younger patients and those most recently exposed to antibiotics at greatest risk, according to a study published in the Journal of the American Society of Nephrology. This is the first study that has linked oral antibiotics to kidney stones. “The overall prevalence of kidney stones has risen by 70 percent over the past 30 years, with particularly sharp increases among adolescents and young women,” said study leader Dr. Gregory E. Tasian, pediatric urologist at Children’s Hospital of Philadelphia. Previously, kidney stones in ... Read More

Certain antibiotics linked to major birth defects

Babies born to women who use certain types of antibiotics while pregnant may be at an increased risk of major congenital malformations, according to a study published in the British Journal of Pharmacology. Other types of antibiotics, however, were not associated with these types of birth defects. The antibiotics of concern include clindamycin, doxycycline, quinolones, macrolides and phenoxymethylpenicillin. Exposure to amoxicillin, cephalosporins, and nitrofurantion did not show this risk. Researchers from the University of Montreal launched the study to better understand the link between gestational antibiotic exposure and major congenital malformations. Using the Quebec pregnancy cohort consisting of nearly 400,000 ... Read More

Antibiotic side effects in 1 in 5 hospitalized patients

Nearly one in five people treated with antibiotics while hospitalized develops an antibiotic-related side effect up to three months after antibiotic therapy, according to a study published in JAMA Internal Medicine. The study involved a review of electronic medical records of 1,488 adults admitted to Johns Hopkins Hospital between September 2013 and June 2014, each of whom received oral or parenteral antibiotics to treat various conditions including trauma or chronic disease. Patients were monitored for up to 90 days after discharge for a potential antibiotic adverse event, including Clostridium difficile (C. diff) infection and new multi-drug resistant infections. Researchers found ... Read More

Some antibiotics increase risk of miscarriage

Women who take common antibiotics early in their pregnancy are at increased risk of having a miscarriage, according to a new study published in the Canadian Medical Association Journal. Classes of antibiotics linked to miscarriage risk include macrolides (Zithromax, Ketek), quinolones (Cipro, Levaquin, Floxin), tetracyclines (Terramycin, Dynacin), sulfonamides (Bactrim, Septra, and metronidazole (Flagyl). Erythromycin (Erythrocin, Benzamycin) and nitrofurantoin (Furadantin, Furalan), often prescribed to pregnant women to treat urinary tract infections, were not associated with an increased risk of miscarriages. Pregnant women are prone to infections, said researcher Dr. Anick Bérard, Faculty of Pharmacy, Université de Montréal, Montréal, Quebec. “Although antibiotic ... Read More

Antibiotics during hospitalization linked to sepsis, septic shock after discharge

Patients who are treated with antibiotics while hospitalized are at a dramatically increased risk of sepsis or septic shock after discharge, according to James Baggs, PhD., with the Centers for Disease Control and Prevention (CDC). Sepsis is a complication caused by the body’s overwhelming and life-threatening response to an infection and can lead to tissue damage, organ failure and death. Septic shock occurs when sepsis leads to dangerously low blood pressure and abnormalities in cellular metabolism. Sepsis is uncommon, but it is 80 percent more likely to occur after treatment with certain antibiotics compared to no treatment with antibiotics, according ... Read More

Alarming Levels of Antibiotic-Resistant Superbugs Found In U.S. Meat

The presence of antibiotic-resistant superbugs in U.S.-produced meat has soared to alarming levels, Consumer Reports has found. The results of a three-year study, published online by Consumer Reports last week in an article called “Making the World Safe from Superbugs,” indicate that the systematic overuse and abuse of antibiotic drugs in the agricultural industry has allowed bacteria to evolve so that antibiotics are useless against them. These are the potentially lethal “superbugs,” which include methicillin-resistant staphylococcus aureus (MRSA) and bacteria resistant to three or more types of antibiotics. In the section of the report titled “Our Flawed Food Supply,” Consumer ... Read More

Antibiotic use linked to childhood obesity

Commonly prescribed antibiotics may be contributing to the nation’s growing childhood obesity epidemic. A new study conducted by researchers at Johns Hopkins Bloomberg School of Pubic Health and published in the International Journal of Obesity, suggests that children given antibiotics gain weight more quickly than those who were not treated with the medication, and the weight they gain can be cumulative and progressive. The study looked at antibiotic use in nearly 164,000 Pennsylvania children. Researchers found that healthy 15-year-olds who had been prescribed antibiotics seven or more times in their lifetime weighed about three pounds more than healthy 15-year-olds who did ... Read More

Woman suffers Stevens Johnson Syndrome, burning ‘from inside out’ after taking a friend’s medication

A young mother is fighting for her life after taking a friend’s prescription antibiotic and suffering an allergic reaction that doctors say is causing her to burn from the inside out. Yassmeen Castanada took the antibiotic on Thanksgiving to help ward off a sickness she felt coming on. But shortly afterward her eyes, nose and throat began to burn. She was rushed to the emergency room where her condition progressed. Within days, blisters covered her body and her skin began to peel off in sheets, causing excruciating pain and exposing her to life-threatening infection. The diagnosis – Stevens Johnson Syndrome ... Read More

Discontinuation of antibiotics before dental procedures linked to increase in heart valve infection

Cutting back on the use of antibiotics before dental work may be to blame for an increase in heart valve infection in patients in England, a new study finds. Certain dental procedures can stir up the bacteria in the mouth and cause them to enter the bloodstream, where they can travel to the heart and cause a life threatening infection known as endocarditis. The heart problem kills 10-20 percent of those infected. People with artificial heart valves and other implants are at high risk of becoming infected with endocarditis, and those with naturally leaky heart valves, called mitral valve prolapse, are ... Read More

FDA recommends limiting antibiotic use in farm animals to help stop antibiotic resistant disease

The Food and Drug Administration (FDA) is moving toward phasing out the use of some antibiotics in farm animals processed for meat in an effort to limit antibiotic resistant disease in humans, a growing public health concern that kills at least 23,000 people a year, according to the Centers for Disease Control and Prevention (CDC). When penicillin was discovered in 1928, it was considered a medical miracle, curing patients of a variety of bacterial infections. It wasn’t long before cattle, hog and poultry producers began routinely giving low doses of the drugs to large numbers of farm animals to prevent ... Read More