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Avastin 16 articles

Cancer drug Avastin with chemo granted priority review for treatment of ovarian cancer

The Food and Drug Administration (FDA) has granted Priority Review status for the cancer drug Avastin (bevacizumab) plus chemotherapy for the treatment of women with recurrent platinum-resistant ovarian cancer. Avastin is already approved to treat specific types of colorectal, lung, kidney, and brain cancers. Avastin was also granted priority review for the treatment of cervical cancer. The Priority Review status is based on data from the Phase 3 AURELIA trial, a multicenter, randomized, open-label study in 361 women with platinum-resistant recurrent epithelial ovarian, primary peritoneal or fallopian tube cancer who have received no more than two anticancer regimens prior to ... Read More

Experimental vaccine shows promise against most aggressive brain tumors

More than 90 percent of patients with a highly reoccurring type of brain cancer treated with an experimental vaccine were alive six months after undergoing surgery, a far better prognosis than patients who followed standard treatment, according to a study published in the journal Neuro-Oncology and accompanied by an editorial highlighting the importance of the trial.  “The grim prognosis is exactly why new research is important,” says Orin Bloch, MD, a neurosurgeon at Northwestern Memorial Hospital and lead author of the study. The tumor, known as glioblastoma multiforme, or GBM, is the same type of tumor that took the life ... Read More

More counterfeit vials of cancer drug Avastin found in US

More counterfeit versions of Roche’s best-selling cancer drug Avastin are being distributed to medical facilities in the United States, the Food and Drug Administration (FDA) warned. This is the third time in a year that federal regulators have discovered counterfeit versions of the widely used drug to treat cancers of the colon, kidneys, lungs and brain. The latest batch of counterfeit Avastin does not contain the active ingredient found in the authentic version. The latest batch of counterfeit Avastin was distributed by Medical Device King and is packaged as Altuzan, the Turkish version of Avastin, which is not approved in the ... Read More

FDA warns medical facilities about counterfeit Botox

Batches of Botox shipped from a Canadian drug supplier to more than 350 medical facilities in the United States may be counterfeit and unsafe, the Food and Drug Administration (FDA) warned. The drugs were shipped by suppliers owned by Canada Drugs, a pharmacy that was previously found to have shipped unapproved and counterfeit cancer drugs. Botox is prescription medication that is injected into muscles and used to treat overactive bladder, chronic migraines, upper limb spasticity, cervical dystonia, certain types of eye muscle problems or abnormal spasm of the eyelids, and excessive underarm sweating. Botox is also used to temporarily improve ... Read More

Roche questioned about unreported possible drug side effects, deaths

Roche, maker of drugs such as the cancer drug Avastin, flu medicine Tamiflu, antianxiety drug Klonopin, and the diet pill Xenical, is being investigated by European drug regulators because of potential deficiencies in the way the drug company reported possible side effects in patients in the United States. The European Medicines Agency identified the problems during a routine inspection of Roche, during which they found about 80,000 reports of possible side effects in drugs sold in the U.S. that had not been followed up on to determine if they were actual adverse reactions that should be reported to drug authorities. The ... Read More

FDA finds second counterfeit cancer drug

The Food and Drug Administration (FDA) has found a second counterfeit cancer drug that has been illegally distributed to medical practices in the United States. Last month, the FDA obtained counterfeit versions of Genetech’s Avastin that contained salt, starch, and a variety of chemicals, but none of the active ingredient bevacizumab that fights cancer. The latest drug, a counterfeit version of Roche’s Altuzan, with the same ingredient, bevacizumab, was also found not to have the active ingredient. Even if the Altuzan obtained was not counterfeit, that drug is not approved by the FDA for use in the United States. (It is ... Read More

Counterfeit cancer drug traced back to distributors in Egypt

Counterfeit vials of the cancer drug Avastin that were found circulating in Europe and the United States earlier this month contain salt, starch and a variety of chemicals, but none of the active ingredient bevacizumab that fights cancer. Avastin is an injectable medicine made by Swiss drug maker Roche. It is administered to patients at clinics, hospitals and doctors’ offices. It is used to treat various forms of cancer including colon, kidney, brain and lung cancers. Avastin made headlines recently when the Food and Drug Administration (FDA) pulled the drug’s breast cancer indication because it was not proven safe or ... Read More

FDA removes breast cancer indication from Avastin

After months of debate, the Food and Drug Administration (FDA) has ordered that the breast cancer indication for the drug Avastin be removed because it is not proven safe and effective to treat the disease. Breast cancer survivors petitioned an FDA advisory panel earlier this year to keep the drug as a breast cancer treatment. “I never thought that in the United States I would have to beg for a drug that is keeping me and many others alive,” a breast cancer survivor told the panel during a hearing last summer. But the pleas of breast cancer victims fell on deaf ... Read More

More patients blinded after Avastin eye treatments

LOS ANGELES – Five patients have been blinded after being injected with Avastin, a cancer drug made by Genentech that is often used to treat some forms of age-related macular degeneration and other eye diseases. The incidents are the latest cases in a series of alleged Avastin-induced blindness to occur in the U.S. On Tuesday, the U.S. Food and Drug Administration issued an alert warning of infection risks associated with the use of Avastin in treating the eyes. The FDA warning was prompted by a similar incident in the Miami area where 12 patients received eye infections following Avastin injections. ... Read More