After nearly two years rife with rejections and requests for more information, Portola Pharmaceuticals’ AndexXa has been approved by the Food and Drug Administration (FDA), as the only antidote to reverse the blood thinning effects of the Factor Xa inhibitor anticoagulants Xarelto and Eliquis, in cases of life-threatening or uncontrolled bleeding. Xarelto and Eliquis work by inhibiting a protein involved in the formation of blood clots. They are used to prevent strokes in patients with the common heart rhythm abnormality atrial fibrillation, to prevent and treat deep vein thrombosis and pulmonary embolism, and to prevent blood clots in patients who ... Read More
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