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Bayer 129 articles

Bayer banks on sales of blood thinner Xarelto

xarelto

Bayer announced it plans to increase sales for its main Healthcare division by 6 percent on average through 2017 to more than $26.7 billion by hanging its hat on new drugs, such as the blood thinner Xarelto. The company says rising sales of these newer drugs have helped offset declines of its birth control pill and multiple sclerosis treatment in the face of competition. Bayer teamed up with Johnson & Johnson subsidiary Janssen Pharmaceuticals to produce Xarelto, which became the second drug in a new class of blood thinners called Xa inhibitors. The anticoagulant is used to prevent or treat blood ... Read More

FDA approves new IUD

mirena IUD

A new intrauterine device (IUD) for birth control has been approved by the Food and Drug Administration (FDA). Liletta, which is already approved in Europe, is similar to Bayer’s Mirena and Skyla IUDs, which work by releasing a small amount of the hormone levonorgestrel. The approval is based on a comprehensive study of 1,751 women during which the device was found to be 99.45 percent effective at preventing pregnancy over a three-year period. The device showed effectiveness in women regardless of age, body mass index, or whether they had previously given birth. The study participants will continue to be followed ... Read More

European drug regulators expand indication for blood thinner Xarelto

xarelto

European drug regulators have expanded the indication for Bayer’s blood thinner Xarelto allowing more types of patients to receive the drug. The National Institute for Health and Care Excellence (NICE) issued a final draft guidance allowing anticoagulant Xarelto to be used in combination with the antiplatelet drug clopidogrel and aspirin, or with aspirin alone, to prevent blood clots in patients who have had a heart attack. Xarelto, which contains the active ingredient rivaroxaban, is already approved to treat and prevent strokes in some heart patients and in patients with deep vein thrombosis or pulmonary embolism, and to prevent blood clots in patients ... Read More

New adverse events listed on safety label of Xarelto blood thinner

xarelto

The safety label for the new blood thinner Xarelto (rivaroxaban) has been updated to include a new adverse reaction for thrombocytopenia, a condition associated with abnormal bleeding, as well as hepatitis and other liver injuries. Xarelto blood thinner, made by Johnson & Johnson unit Janssen Pharmaceuticals and Bayer, is an anticoagulant used to treat or prevent blood clots in some heart patients and patients undergoing knee or hip replacement surgery. It is in a new class of blood thinners known as Xa Inhibitors, which also includes the brand name drugs Pradaxa and Eliquis. This class of drugs is the first ... Read More

Doctors paid millions to promote dangerous new blood thinners

xarelto

Pharmaceutical companies pushing novel new anticoagulants paid doctors nearly $20 million to promote their blood thinner drugs during the last five months of 2013, according to a Pro Publica analysis of Sunshine Act data. Pfizer and Bristol-Myers paid $8 million for doctors to market Eliquis – more than any other drug during that time period. Johnson & Johnson subsidiary Janssen Pharmaceuticals and Bayer paid nearly $7 million to promote Xarelto, and Boehringer Ingelheim shelled out nearly $5 million to push Pradaxa. Pradaxa was the first to be approved in 2010, followed by Xarelto and then Eliquis. All three blood thinners ... Read More

Cardiologists raise concerns about bleeding risks with Pradaxa, Xarelto, Eliquis

xarelto

When a group of medical experts gathered last April for the Cardiac Safety Research Consortium (CSRC) at the Food and Drug Administration (FDA) headquarters in White Oak, Md., it was to discuss the best way to deal with bleeding events that occurred with a group of newer anticoagulants. The drugs, Pradaxa (dabigatran), Xarelto (rivaroxaban) and Eliquis (apixaban) hit the market within the past five years and have all but replaced the long-used warfarin for the treatment and prevention of blood clots and strokes in some heart patients and patients who have undergone knee or hip replacement surgery. However, the blood ... Read More

No antidote available for newer blood thinners Pradaxa, Xarelto, Eliquis

xarelto

The new blood thinners Pradaxa (dabigatran), Xarelto (rivaroxaban), and Eliquis (apixaban) may be more convenient for patients than the long-used anticoagulant warfarin because users do not have to be regularly monitored as they do with warfarin. However the newer medications are lacking a one thing that warfarin has – a lifesaving antidote that can reverse the bleeding effects of the drug. Blood thinners are designed to prevent or treat blood clots and strokes in some heart patients and in patients who have undergone knee or hip replacement surgery. Warfarin has been used for decades as a treatment but patients had to ... Read More

Woman files Xarelto side effects lawsuit

xarelto

Bernadette Fuller is suing Janssen, a subsidiary of Johnson & Johnson, and Bayer Healthcare Pharmaceuticals claiming the drug companies promoted their blood thinner Xarelto as a safe and effective treatment for the prevention of strokes in some patients but failed to warn that the drug could cause gastrointestinal bleeding and other serious bleeding events including ones that required transfusions. Xarelto was approved by the Food and Drug Administration (FDA) three years ago based on data from clinical trials that touted positive results. However, during those same trials the companies learned that the drug could cause bleeding events. The lawsuit claims that ... Read More

Study links Mirena IUD to increased risk of breast cancer

mirena IUD

Women who use intrauterine devices (IUDs) that release the hormone levonorgestrel, such as the Mirena IUD may be at an increased risk of breast cancer, according to a new study published in the journal Obstetrics and Gynecology. Levonorgestrel is a synthetic form of the hormone progesterone which is naturally produced in a woman’s body to regulate ovulation. Not only does it hinder conception, it also strengthens the uterine lining, which reduces heavy menstrual bleeding. Not only is the Mirena IUD approved by the Food and Drug Administration (FDA) to prevent pregnancy, it is also used to treat heavy periods, endometriosis ... Read More

Bleeding risks associated with new blood thinners Xarelto, Pradaxa

xarelto

Advertisements warning of bleeding risks with new blood thinners including Pradaxa and Xarelto leave many people asking if the drugs are worth the risk. Blood thinners, also called anticoagulants or antiplatelets, are often prescribed to patients with some heart or blood vessel diseases, or for people with poor blood flow to the brain. These drugs reduce the risk of heart attack and stroke by reducing the formation of blood clots in the arteries and veins. There are two main types of blood thinners – anticoagulants and antiplatelets. Anticoagulants include the drugs heparin and warfarin, which work on chemical reactions in ... Read More