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Belsomra 3 articles

Belsomra sleeping pill linked to suicides

Cases of completed suicides and attempted suicides with the insomnia drug Belsomra have raised concerns with the Institute for Safe Medication Practices (ISMP) in its QuarterWatch review. The organization monitors Food and Drug Administration (FDA) MedWatch adverse event reports each quarter. Belsomra was approved by the FDA in 2014. It contains the active ingredient suvorexant, which works by blocking two newly discovered neurotransmitters called orexins. Neurons that emit orexin send wakefulness signals to the complex neural circuits that regulate sleep and waking cycles. Belsomra was developed under the idea that blocking these wakeful signals at night would help people sleep. During ... Read More

Cases of worsening insomnia linked to sleep aid Belsomra

In August 2014, the Food and Drug Administration (FDA) announced the approval of a novel new sleeping pill, Belsomra. The drug was the first in a class known as an orexin receptor antagonist designed to regulate the sleep-wake cycle in people who suffer from insomnia. But new reports suggest the drug may have “paradoxical reactions,” and cause a worsening of insomnia in some patients. Insomnia is characterized by difficulty falling asleep or staying asleep. It can range from mild to severe, depending on how often it occurs and for how long. Insomnia can cause daytime sleepiness and lack of energy, ... Read More

New sleeping pill gets FDA approval, awaits DEA clearance

A new type of prescription sleep aid has won approval from the Food and Drug Administration (FDA) and if given clearance from the Drug Enforcement Administration (DEA) should be commercially available later this year. Belsomra, made by Merck & Co., works by temporarily blocking chemicals in the brain that control sleep cycle and keep people awake at night. The sleeping pill is designed to help people with insomnia to sleep through the night. Belsomra was approved based on trials that pitted the medication against a placebo. It was not tested against other sleep aids, however, so it is not known ... Read More