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blood clots 301 articles

Pharmaceutical companies developing drugs to fight blood clots

Five pharmaceutical companies are working on new medications to treat blood clots, also known as thrombosis, according to The Wall Street Journal. Thrombosis is a serious problem affecting nearly 900,000 Americans each year, and resulting in nearly 300,00 deaths annually. Currently, heparin and Vitamin K antagonists are the only two principal treatments for blood clots. The blood thinner heparin made news recently when the FDA recalled batches of heparin after more than 80 people died and several others became ill after receiving heparin. It was later determined that heparin made by Baxter International was contaminated in the company’s Chinese manufacturing ... Read More

HRT linked to recurrence of breast cancer

Once thought of as a cure-all for a host of menopausal symptoms with benefits ranging from increased bone strength and protection against heart disease, hormone replacement therapy (HRT) continues to come under fire for causing more harm than good. Now researchers believe that women who survived breast cancer and then took HRT to relieve menopause symptoms may be at a significantly higher risk for breast cancer recurrence, according to Natural News. According to the report, Kings College London researchers tracked 442 female breast cancer survivors for more than four years, half of which had been given HRT. The women who ... Read More

Timing, method of HRT may affect heart attack risk

How and when women take hormone replacement therapy (HRT) may affect their risk of heart attack, according to the Washington Post. For six years, Danish researchers tracked nearly 700,000 healthy Danish women aged 51 to 69. While researchers found no increased risk of a heart attack in women who were currently using HRT compared with women who had never used HRT, there was a 24 percent increased risk among women aged 51 to 54, and an increased risk in women of the same age group taking the prescribed medications for a long period of time. The study found that older ... Read More

October is breast cancer month; time to evaluate breast health

October is breast cancer awareness month, which makes it a perfect time for women currently taking or considering taking hormone replacement therapy (HRT), to assess their breast health. For years, HRT was considered the cure-all for menopausal symptoms that range from hot flashes and riding the emotional roller coaster to bone loss and osteoporosis. But a 2002 study by the Women’s Health Initiative (WHI) and funded by the National Institutes of Health stopped women and their doctors in their tracks when the research revealed that the risks of HRT far outweighed and outnumbered the benefits. The WHI report stated that ... Read More

consumer group urges Ortho Evra ban

Public Citizen, an 80,000-member nonprofit organization dedicated to consumer advocacy, petitioned the FDA to ban Johnson & Johnson’s contraceptive patch Ortho Evra (ethinyl estradiol/norelgestromin). The organization requested complete removal of the contraceptive within 6 months. Clinical data show that the Ortho-Evra patch carries greater risks compared to standard contraception in pill form without providing any real benefits. Public Citizen’s petition listed several reasons why the patch should be banned, including: Potentially toxic levels of synthetic estrogen, up to 60% more on average Greater variability in estrogen levels than standard oral birth control / inconsistent dosages depending on where on the ... Read More

Heparin Linked to Severe Allergic Reactions

FDA advises health care practitioners to switch suppliers and limit use of drug until problem identified The U.S. Food and Drug Administration announced today that Baxter Healthcare Corporation has temporarily stopped manufacturing multiple-dose vials of the injectable blood-thinning drug heparin due to reports of serious allergic reactions and hypotension (low blood pressure) in patients who receive high “bolus” doses of the drug. Serious reactions to the drug have included difficulty breathing, nausea, vomiting, excessive sweating, and rapidly falling blood pressure that can lead to life-threatening shock. Four people have died after receiving heparin, although the relationship to the drug is ... Read More

Ortho Evra birth control patch label change

The FDA approved a label change to Johnson & Johnson’s Ortho Evra birth control patch on January 18, 2008. The patch has been known to cause blood clots which can lead to pulmonary embolism and death. The label change comes after testing revealed women on the patch between the ages of 15-44 are at a higher risk for pulmonary embolism. Currently there is litigation pending throughout the United States, including in Chicago, relating to the use of the Ortho Evra patch. Plaintiffs have filed claims after suffering from blood clots, pulmonary embolisms and in some cases death. The side effects ... Read More

Ohio Supreme Court upholds law that puts cap on personal injury damages

In a 5-2 decision, the Ohio Supreme Court Thursday morning upheld the constitutionality of a 2004 law capping damages for pain, suffering, and other non-economic claims in personal injury and other lawsuits. In a response to a question posed by U.S. District Court in Toledo, which is considering a federal lawsuit stemming from Johnson & Johnson’s Ortho Evra birth-control patch, the court’s majority found that the General Assembly had the authority to enact the law. “Some may think limitations on certain damages to be unwise legislative policy-making, but it is beyond the authority of any court to write into the ... Read More

Ortho Evra lawsuit settled for $1.25m as J&J tries to avoid public trials

Ortho Evra manufacturer, Johnson & Johnson, recently settled a lawsuit with the family of a 14-year-old girl killed by the defective birth control patch. The case is just one of many Ortho Evra lawsuits settled by Johnson & Johnson prior to going trial. It likely hints at the company’s desire to avoid trials where its actions -or lack thereof – regarding safety problems with the defective Ortho Evra birth control patch could be called into question. When Ortho Evra was introduced in 2002, Johnson and Johnson touted the once-weekly patch as a convenient alternative to daily oral contraceptive pills. The ... Read More

J&J pays $1.25m to settle lawuit over death of 14-year-old

Johnson & Johnson agreed to pay $1.25 million to settle a lawsuit over the death of a 14-year-old girl who used the company’s Ortho Evra birth-control patch, according to court records. The confidential agreement involved Alycia Brown, a resident of LaCrosse, Wisconsin, who suffered two blood clots in her lungs on May 7, 2004, after using the patch for several weeks. J&J, the world’s largest maker of health-care products, faces lawsuits by 2,400 of the 5 million women who used the patch. Most claim they suffered strokes or clots in their legs or lungs. The company settled dozens of cases ... Read More