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blood clots 301 articles

FDA says testosterone therapy serves little benefit to men

There is little evidence to show that testosterone replacement products serve any benefit to men, the Food and Drug Administration (FDA) announced this week. Testosterone treatments are prescribed to treat low testosterone levels in men resulting in symptoms such as fatigue, weight gain, muscle loss and low sex drive. Aggressive marketing campaigns from drug companies pushing testosterone products have resulted in skyrocketing prescriptions for testosterone drugs, leading some to wonder how many men are taking the drug who don’t really need it. This is especially worrisome considering two recent studies have linked testosterone supplement use to an increased risk of ... Read More

Testosterone therapy poses same safety risks to young men, teenagers

Young men and teenagers hoping to improve in sports are turning to testosterone boosting products, raising concerns about their long-term health. Testosterone replacement therapy is a prescription drug indicated for men whose blood levels show lower than normal levels of the male hormone, resulting in symptoms such as low sex drive, weight gain and fatigue. The treatment can also help build muscle mass, which makes it an attractive supplement to body builders and athletes. Many professional sports have cracked down on the use of performance enhancing drugs, which include testosterone therapy. However, some gyms sell testosterone supplements, says Chad Zimmerman, ... Read More

Testosterone therapy does not appear to work in obese men with type 2 diabetes

Testosterone replacement therapy is designed to treat symptoms of “Low T,” such as low libido, weight gain, and fatigue; however, the treatment doesn’t appear to work on aging, obese men with type 2 diabetes, a new study shows. The new study published in The Journal of Clinical Endocrinology & Metabolism, found that testosterone supplements do not improve erectile dysfunction or general health in this population because testosterone levels are not the only issue causing their symptoms. The findings raise even more question about the controversial hormone supplements. Prescriptions for testosterone therapies, such as the widely used Androgel, Axiron and Testim, have skyrocketed ... Read More

Canadian regulators warn consumers about cardiovascular risks of testosterone drugs

Canada’s national health regulators have issued a warning to consumers and health care providers about the serious risks associated with the use of testosterone-replacement drugs, which are being prescribed to increasing numbers of men as a treatment for low natural testosterone levels. Health Canada said its safety review of testosterone drugs involved evaluating the currently available studies and reports on the cardiovascular risks the drugs presented. In the course of its safety review, the agency found “a growing body of evidence suggesting a possible association between the use of testosterone replacement products and cardiovascular risk.” As in the U.S., men ... Read More

Did Boehringer Ingelheim withhold safety information about blood thinner Pradaxa?

When Pradaxa (dabigatran) hit the market in 2010 to prevent strokes in patients with atrial fibrillation, it became the first alternative treatment to the long-used warfarin for patients with the condition. What made Pradaxa so attractive compared to warfarin (Coumadin) is that patients taking Pradaxa did not have to have their blood monitored on a regular basis in order to prevent potentially deadly bleeding events. However, a British Medical Journal investigation has found that Boehringer Ingelheim, maker of Pradaxa, withheld information that showed patients taking Pradaxa who underwent routine drug level monitoring and dose adjustment could cut bleeding risk by ... Read More

New blood clot warning added to safety labels of testosterone replacement therapies

The safety labels of testosterone replacement treatments have been updated to include warnings of an increased risk of life threatening blood clots. The update comes on the heels of a Food and Drug Administration (FDA) safety alert notifying the public that during an ongoing investigation into cardiovascular risks with testosterone treatments, researchers uncovered a number of reports of thromboembolic events, or blood clots, in men using the hormone replacement products. The new warnings were added to the labels of the following testosterone therapies: Androderm transdermal system, AndroGel gel (1% and 1.62%), Aveed injection, Delatestryl injection, Fortesta gel, Striant buccal system, ... Read More

Testosterone therapy prescribed generously despite potentially dangerous side effects

The number of prescriptions for testosterone replacement therapy for men 40 years of age and older has risen 300 percent between 2001 and 2011, and a quarter of the most recent testosterone therapy users have never had their blood levels checked to determine if the need the medication, according to a study published in JAMA Internal Medicine. The research was spearheaded by Jacques Baillargeon, an epidemiologist at the University of Texas Medical Branch in Galveston, who wondered if the increase in advertising for testosterone treatments was resulting in an increase in prescriptions for the drugs. The ads offered relief from ... Read More

Vials of blood thinner Coumadin recalled due to possible contamination

Six lots of the commonly prescribed blood thinner Coumadin (warfarin) are being recalled because visible particulate matter was found in some vials of the drug. If injected, particulate – whether of metallic or non-metallic cellulose matter – can cause serious and potentially fatal adverse reactions including embolization, as well as allergic reactions. Coumadin is a prescription medication used to treat blood clots and to lower the risk of blood clots forming in the body. It is available in both an oral and an injectable formulation. The injectable formulation is typically administered in a hospital setting by health care professionals to ... Read More

New study raises questions about safety of testosterone replacement therapy

A new study raises questions about the link between testosterone replacement therapy and heart attacks. Researchers at the University of Texas, Medical Branch at Galveston, studied more than 25,000 men, all Medicare beneficiaries older than 65 who were treated with testosterone injections for up to eight years. These men were compared to about 19,000 men of the same age who did not use testosterone treatments. Researchers found that testosterone users were not at greater risk of having a heart attack compared to nonusers of testosterone therapy. Researchers did not track strokes, blood clots, dementia or death. The results contradict several ... Read More

MBL granted A-Rod therapeutic use exemption for testosterone therapy

Yankees third baseman Alex Rodriguez, best known as A-Rod, was using a testosterone treatment during the 2007 season under a therapeutic use exemption from Major League Baseball, according to a new book titled Blood Sport: Alex Rodriguez, Biogenesis and the Quest to End Baseball’s Steroid Era. Testosterone supplements are a prescription medication approved by the Food and Drug Administration (FDA) to boost testosterone levels in men who have low levels of the hormone in their blood, a condition known as hypogondalism. The condition can result in symptoms such as low libido, weight gain, and fatigue. In recent years, aggressive marketing ... Read More