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blood infections 4 articles

FDA adds new warnings to class of type 2 diabetes drugs

New warnings for serious and life threatening side effects have been placed on the safety labels of a new class of type 2 diabetes medications, which includes the brand names Invokana, Invokamet, Jardiance, and Farxiga. The drugs, known as sodium-glucose cotransporter-2 (SGLT2) inhibitors, work on the main site of filtered glucose reabsorption in the kidneys, resulting in the reduction of glucose reabsorption and increasing urinary excretion of glucose, thus lowering blood sugar levels in the body. A recent review by the Food and Drug Administration (FDA) into growing adverse event reports found that between March 2013 to May 2015, 73 ... Read More

FDA warns of serious urinary tract infections, ketoacidosis with SGLT2 diabetes drugs

New warnings have been added to the safety labels of some type 2 diabetes drugs known as sodium-glucose cotransporter-2 (SGLT2) inhibitors about side effects of too much acid in the blood and serious urinary tract infections, both of which may require hospitalization, the Food and Drug Administration (FDA) announced in a Safety Alert. In May 2015, the FDA launched an investigation into the risk of ketoacidosis with SGLT2 inhibitors after a review of the agency’s adverse event data revealed 73 cases of ketoacidosis from March 2013 to May 2015 in patients with type 1 or type 2 diabetes treated with ... Read More

Fresenius faces more lawsuits over generic drugs

Fresenius Kabi, one of four business segments of the worldwide dialysis service and product provider Fresenius Medical Care, is being accused by drugmaker Cubist Pharmaceuticals of infringing on four patents for the intravenous antibiotic Cubicin, used to treat skin and blood infections. Cubist’s lawsuit comes nearly two months after Fresenius Kabi informed Cubist that it planned to seek Food and Drug Administration (FDA) approval for the drug before the patents expired, claiming the patents were invalid, unenforceable or wouldn’t be infringed upon by Fresenius’ product. Cubist’s lawsuit maintains the company will be irreparably harmed by Fresenius’ competing product. Cubicin, the ... Read More

Study: Fresenius blood volume product increases risk of death in critically ill patients

A product made by Fresenius and B. Braun Holding to increase blood volume in critically ill patients increases the risk of death and kidney damage and should no longer be used, a researcher with the London School of Hygiene and Tropical Medicine recommended. Hydroxyethyl starch solution, also known as colloid fluid or crystalloid fluid, is used to stabilize patients with low blood pressure caused by conditions such as dehydration, blood loss, shock, and organ damage from blood infections. Hydroxyethyl starch is widely used in Europe, the UK and Canada, but not as popular in the U.S. An alternative fluid for ... Read More