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blood pressure 21 articles

FDA approves new diet pill Contrave

A new prescription diet pill has been given clearance by the Food and Drug Administration (FDA) for marketing in the United States. Contrave, made by Orexigen Therapeutics, is a combination of bupropion, an antidepressant that is also used for smoking cessation, and naltrexone, a drug used to treat drug and alcohol dependence. Contrave is approved for overweight or obese patients with a body mass index (BMI) of 30 or higher, as well as people with a BMI of 27 or higher with at least one other health issue such as diabetes. Patients treated with Contrave lost an average of 4.2 ... Read More

Novel new diabetes treatment fares well in clinical trials

Clinical trials on a novel new type 2 diabetes treatment lowered glucose, did not increase lipids, and was well tolerated in patients with the chronic disease. The drug is an investigative liver-selective glucokinase activator, or GK activator, referred to as TTP399. It is a key regulator of glucose homeostasis. It is a member of the Hexokinase family and is expressed in the endocrine cells of the Langerhans islets of the liver, in the L- and K-cells of the intestines, and in the neurons of the central nervous system, in particular the hypothalamus. GK modulates blood glucose by inducing glucose-stimulated insulin ... Read More

FDA finds cardiovascular risk with blood pressure medication used by diabetics is inconclusive

There is no clear evidence that the blood pressure medication olmesartan increases the risk of cardiovascular events in diabetic patients, the Food and Drug Administration (FDA) said in a Drug Safety Communication. The FDA began a safety review of olmesartan in 2010 after results from the ROADMAP (Randomized Olmesartan and Diabetes Microalbuminuria Prevention) clinical trial raised cardiovascular risk concerns. The clinical trial was designed to see whether olmesartan could delay kidney damage in patients with type 2 diabetes. There was an unexpected finding of an increased risk of cardiovascular death in patients treated with olmesartan compared to patients given a ... Read More

New black box warning for birth defects, infant death added to hypertension meds

Women of childbearing age using the hypertension drugs Hyzaar or Cozaar should be counseled about the consequences of using the medication if they become pregnant, and women who become pregnant while taking the drug should discontinue it as soon as possible due to new studies that show the drugs may put developing fetuses at risk for birth defects and death. Hyzaar (losartan potassium hydrochlorothiazide) and Cozaar (losartan potassium) are drugs that work directly on the renin-angiotensin system, a hormone system in the body that regulates blood pressure and water or fluid balance. They are in a class of drugs known ... Read More

FDA to take closer look at impact of caffeinated foods on children, teens

The Food and Drug Administration (FDA) will take a “fresh look” at the potential impact foods with added caffeine have on children and adolescents. The agency’s announcement comes just as Wrigley’s launched its new Alert Energy Caffeine Gum. One piece of the gum contains 40 milligrams of caffeine, about the same as a half-cup of coffee. Wrigley’s says the gum is not meant for people under age 25 and even has a slightly bitter taste to dissuade children, higher price and packaging that differentiate it from other chewing gum. Throughout the years, food companies have started adding caffeine to their ... Read More

FDA warns against using dietary supplements containing DMAA

The Food and Drug Administration (FDA) is warning consumers that dietary supplements promising weight loss, muscle building and performance enhancement containing dimethylamylamine (DMAA) can be dangerous and even deadly and should be avoided at all costs. The agency is working hard to remove all DMAA-containing supplements from the marketplace, however some companies continue to sell the products illegally. DMAA can elevate blood pressure and could lead to cardiovascular problems including heart attacks, shortness of breath, and tightening in the chest. Given the known biological activity of DMAA, the ingredient may be particularly dangerous when used with caffeine. As of April ... Read More

New study shows energy drinks can raise blood pressure, cause abnormal heart rhythm

A new study shows that energy drinks, such as Red Bull, Monster, and 5-Hour Energy, may increase blood pressure and cause erratic heartbeat. The new study is an analysis of seven previous studies, and was presented this week at the American Heart Association meeting in New Orleans. The data showed that high energy drinks disturb the heart’s rhythm which, over time, may raise blood pressure and cause an irregular heartbeat, which can be deadly. Energy drinks are not regulated by the Food and Drug Administration (FDA). Caffeinated drinks, such as sodas, can have as much as 71 milligrams of caffeine per 12 ounces, ... Read More

Study: ADHD diagnoses increasing by ‘epidemic proportions’

The prevalence of children diagnosed with attention deficit/hyperactivity disorder (ADHD) in the past decade has reached epidemic proportions in the United States, with diagnoses increasing by nearly 25 percent in that time, according to researchers with the Kaiser Permanente Southern California Medical Group in Pasadena. “It is one of the most common chronic childhood psychiatric disorders, affecting 4 percent to 12 percent of all school-age children and persisting into adolescence and adulthood in approximately 66 percent to 85 percent of children,” according to study material published by MedPage Today. “This large cohort study with children from diverse racial/ethnic and socioeconomic ... Read More

Pepsi launches ‘fat-blocking’ soda in Japan

Pepsi-Cola is launching a new soft drink in Japan that claims to block fat. The new Pepsi Special contains “indigestible dextrin,” also known as dietary fiber, that it claims reduces the amount of fat that’s absorbed into the body and quells the rise of triglycerides in the blood. Dietary fiber is found naturally in foods such as fruits and vegetables, and a diet rich in natural fiber can help regulate the digestive system, lower cholesterol and may even lower the risk of heart disease. Experts are not completely sold on the product, arguing that synthetic fibers may not be as ... Read More

Family sues Monster energy drink maker over daughter’s cardiac arrest

The family of a 14-year-old girl is suing Monster Beverage Company, alleging the company’s energy drink caused her death. The news comes on the heels of a Food and Drug Administration (FDA) investigation into reports of five deaths that may be linked to the Monster beverages. Monster is the top-selling energy drink in the United States, and is packed with 240 milligrams of caffeine, or the equivalent of 7 12-ounce cans of Coca-Cola. A company spokesperson says Monster is unaware of any fatalities that were caused by its drinks. The deceased girl whose family filed the lawsuit had a heart ... Read More