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blood thinners 15 articles

Did Boehringer Ingelheim withhold safety information about blood thinner Pradaxa?

When Pradaxa (dabigatran) hit the market in 2010 to prevent strokes in patients with atrial fibrillation, it became the first alternative treatment to the long-used warfarin for patients with the condition. What made Pradaxa so attractive compared to warfarin (Coumadin) is that patients taking Pradaxa did not have to have their blood monitored on a regular basis in order to prevent potentially deadly bleeding events. However, a British Medical Journal investigation has found that Boehringer Ingelheim, maker of Pradaxa, withheld information that showed patients taking Pradaxa who underwent routine drug level monitoring and dose adjustment could cut bleeding risk by ... Read More

FDA warns health care providers to carefully consider spinal catheters in patients using blood thinners

Physicians should carefully consider the timing of spinal catheter placement and removal in patients taking blood thinners such as Lovenox (enoxaparin), and delay dosing of the drugs for some time interval after the catheter is removed to decrease the risk of spinal column bleeding and subsequent paralysis after spinal injections, including epidural procedures and lumbar punctures, the Food and Drug Administration (FDA) advised. The new recommendations will be added to the labels of all anticoagulants known as low molecular weight heparins, which include the brand name Lovenox as well as generic versions of enoxaparin and similar products. Spinal column bleeding, ... Read More

Clinton’s head injury, blood clot could have been deadly if left untreated

Secretary of State Hillary Clinton is expected to make a full recovery from a rare blood clot in a vein between her brain and skull. Doctors suspect that the blood clot formed after Clinton suffered a concussion after fainting in her home during a bout with the stomach flu. She is being treated with blood thinners. If left untreated, medical experts say the blood clot could have grown large enough to cause a major blockage of blood, which would have led to swelling and even death. In 2009, acclaimed actress Natasha Richardson, wife of actor Liam Neeson, suffered a traumatic head ... Read More

Atrial fibrillation treatment digoxin tied to increased risk of death

A study published in the European Heart Journal says the heart drug digoxin, a treatment for the common irregular heart rhythm disorder known as atrial fibrillation, has been tied to a 41 percent increase in death. But researchers say the deaths my not entirely be the fault of digoxin. The study, conducted by researchers at the University of Kentucky, involved 4,060 atrial fibrillation patients. Half were prescribed digoxin while others were given different heart medications or treatments. During the course of the study 666 patients died and 375 of them had been on digoxin at their last follow-up visit. Researchers ... Read More

Blood thinners more dangerous for people with clotting disorders

Bleeding disorders are more common than most people realize, and often go undiagnosed. The most common type of bleeding disorder is von Willebrand disease (VWD), a condition in which the blood does not clot properly. When injury occurs in patients with VWD, clots usually take longer to form and bleeding is more difficult to stop. There are three types of VWD and each ranges in severity. Because some medications can aggravate the symptoms of VWD, early diagnosis is key. Unfortunately, the disease can be difficult to diagnose. People with VWD may have frequent or hard-to-stop nosebleeds that happen spontaneously, occur ... Read More

FDA undertaking priority review of new anti-clotting drug

The Food and Drug Administration (FDA) is undertaking a priority review for an experimental anti-clotting drug for the prevention of strokes and systemic embolism in patients with atrial fibrillation, an irregular heartbeat that raises the risk for serious blood clots. Eliquis, made by Pfizer and Bristol-Myers, was recently approved in the European Union (EU) for prevention blood clots in patients who have had knee or hip replacement surgery. The EU is currently reviewing the possibility of approving the drug for use with atrial fibrillation patients as well. Anti-clotting agents, also known as coagulants or blood thinners, include medications such as ... Read More

Four drugs send most elderly patients to the hospital

Nearly 100,000 hospitalizations every year are related to adverse drug reactions and unintentional overdoses, and nearly half of those hospitalized are adults 80 years of age or older, according to a study published this month in the New England Journal of Medicine. Researchers say the major culprits are four drugs – warfarin, oral antiplatelet medications such as aspirin, insulins, and oral hypoglycemic agents used to treat diabetes. The study also pointed out that better management of antithrombotic and anti-diabetic drugs could reduce the number of emergency admissions by thousands. The study identified a small group of blood thinners, such as ... Read More

Diabetes drugs sent thousands to emergency room last year

Diabetes drugs such as Actos and Avandia are among the four categories of medications responsible for two-thirds of emergency room visits in people over the age of 65, according to a new study published in the New England Journal of Medicine. Other categories that have been found to cause problems include the blood thinner warfarin and oral anti-platlet drugs like Plavix, both of which are taken for heart disease. The study reviewed nearly 100,000 emergency hospitalizations for adverse drug reactions, such as allergic reactions, and found that many could have been avoided with proper medical follow-ups, monitoring and patient education. ... Read More

Trellis device offers safer and more effective treatment for blood clots

Rose Kirby, 22, was vacuuming out her car when she felt a strange discomfort in her arm. Within an hour it turned into “a pink balloon,” she said. She passed it off as a bug bite or some sort of allergic reaction, but her parents were skeptical. “I was really lucky that my parents made me go to the doctor that day,” she said. What doctors discovered on Rose’s arm was a 10-inch blood clot that stretched from the base of her upper arm to her chest. They say it was caused by Rose’s birth control pills. Large clots like ... Read More

Heart device may eliminate need for heparin, warfarin

A small device implanted in the heart to stop blood clots from triggering strokes could serve as an alternative to blood thinners such as heparin and warfarin, according to a new study conducted by the device’s maker, Atritech, Inc. The device, called the Watchman, is designed specifically for patients with atrial fibrillation, a type of irregular heartbeat. Blood tends to pool in the atrial chamber of individuals with atrial fibrillation, which can lead to clotting and an increased risk for strokes. Patients with atrial fibrillation are generally treated with blood thinners to help prevent blood clots from forming. However, blood ... Read More