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cardiovascular problems 13 articles

Lawsuit filed against Pfizer related to testosterone replacement drug

Pfizer’s testosterone replacement treatment Depo-Testosterone has become the subject of lawsuits questioning the safety and efficacy of the drugs after reports of heart attacks, strokes and blood clots in patients treated with the hormone. The lawsuit filed on behalf of Alvaro Roman Gutierrez alleges that Pfizer and its unit Pharmacia & Upjohn Co. LLC, conducted a “disease mongering” campaign to exaggerate the problem of low testosterone levels in men in order to boost sales of Depo-Testosterone. Gutierrez claims that Pfizer and Pharmacia & Upjohn spent millions of dollars to promote its drug to consumers and, along with other drug companies not ... Read More

Young, African-American dialysis patients at greater risk of dying

Young African-Americans on dialysis are 1.5 times more likely to die than white dialysis patients, according to a study published in the Journal of the American Society of Nephrology. The study, involving more than 11,000 patients, found the young African-American kidney patients most at risk of dying were those living in poorer neighborhoods. Part of the problem was diet and genetics. However, young dialysis patients in general – specifically those between the ages of 18 and 30 – tend to feel more invincible, said researcher Dr. Tanya Johns. “We do find a lot of the young adults tend to do ... Read More

RegenESlim appetite control capsules recalled due presence of dangerous ingredient

Certain lots of RegenESlim appetite control dietary supplements are being recalled because they contain an ingredient that may cause deadly side effects. A Food and Drug Administration (FDA) analysis found in two lots of RegenESlim the presence of DMAA, also known as 1,3-dimethylamylamine, methylhexanamine, or geranium extract, commonly used as a stimulant, pre-workout, and weight loss ingredient in supplements. The agency has warned that DMAA is potentially dangerous to health as it can narrow blood vessels and arteries, which can cause a rise in blood pressure or other cardiovascular problems such as shortness of breath, arrhythmias, tightening in the chest, ... Read More

Fresenius may open new dialysis clinic in Louisiana despite AG’s lawsuit

Fresenius Medical Care, the world’s largest provider of dialysis products and services, is proposing to build a new dialysis center in Terrytown, La., despite being slapped with a lawsuit by the state’s Attorney General earlier this month. Fresenius owns nearly 100 dialysis clinics in Louisiana. The company uses its brand-name products in its facilities and also sells them to non-Fresenius-owned clinics. The state’s lawsuit claims that Fresenius’s dialysis concentrates GranuFlo and NaturaLyte caused patients to suffer from injuries including sudden cardiac arrest, and that the company violated Louisiana law and attempted to defraud dialysis clinics, physicians, the state and its residents by ... Read More

Philadelphia man claims Testim testosterone treatment gave him a heart attack

A 67-year-old Philadelphia man with no history of cardiovascular problems has filed a lawsuit against the makers of his testosterone replacement product claiming the drug caused him to suffer a heart attack. The lawsuit states that the injury was caused by the “exogenously administered testosterone-containing Testim,” a prescription drug made by Auxilium Pharmaceuticals and GlaxoSmithKline. Edwin Rios had been using Testim for a year when he had the heart attack. Testosterone replacement products are designed to boost the hormone’s levels in men who are experiencing symptoms of low testosterone such as weight gain, mood swings, and low libido. Testim was ... Read More

FDA warns against using dietary supplements containing DMAA

The Food and Drug Administration (FDA) is warning consumers that dietary supplements promising weight loss, muscle building and performance enhancement containing dimethylamylamine (DMAA) can be dangerous and even deadly and should be avoided at all costs. The agency is working hard to remove all DMAA-containing supplements from the marketplace, however some companies continue to sell the products illegally. DMAA can elevate blood pressure and could lead to cardiovascular problems including heart attacks, shortness of breath, and tightening in the chest. Given the known biological activity of DMAA, the ingredient may be particularly dangerous when used with caffeine. As of April ... Read More

Chemical in some personal care products linked to heart disease, failure

A chemical used in many antibacterial soaps and personal-care products may have the potential to contribute to heart disease and heart failure, according to a new study published in the Proceedings of the National Academy of Sciences. The chemical, triclosan, was introduced in the 1970s and has since become an increasingly popular ingredient in a variety of products from deodorants and soaps to toothpastes and mouthwashes. A new study has revealed that exposure to the compound has been associated with muscle function impairments in humans and mice, and has even caused the slowing of swimming fish. The chemical reduces contractions ... Read More

Study: Diabetics more likely to suffer mental decline

People who suffer from diabetes may be at greater risk for mental decline, according to a new study published in the Archives of Neurology. For the study, researchers analyzed data from 3,069 people participating a long-term study of older adults living in Pittsburgh and Tennessee. Over the course of 10 years, participants were given repeated cognitive tests that evaluated memorization skills, dexterity, coordination and overall mental health. Researchers found that during a 10-year period, older people with diabetes had much lower cognitive test scores than people of the same age who were not diabetic. People diagnosed with type 2 diabetes ... Read More

Heavy marketing of testosterone gel results in 115 percent increase in use

Heavy marketing campaigns by makers of testosterone replacement products have dramatically increased the use of the products among men in Australia, according to Pharmaceutical Benefits Scheme (PBS), the country’s national drug benefit program. According to PBS statistics, use of testosterone products among men has grown 115 percent from 2005 to 2010. The organization is blaming advertisements that warn low testosterone levels can result in low energy, low sex drive, and fatigue. The ads encourage men to see their doctors, have their hormone levels checked, and to request a particular testosterone gel by name. The products are intended for men who have ... Read More

Development of new cholesterol drug halted due to lack of efficacy

Development on a potential blockbuster cholesterol drug has been halted by the manufacturer because the medication failed to provide benefit when added to existing standard of care in patients with coronary heart disease. A pharmaceutical product is considered a “blockbuster drug” if it generates more than $1 billion of revenue for its owner annually. Roche Holding AG’s dalcetrapid is one of several cholesterol drugs in development known as CETP inhibitor. This class is designed to raise “good cholesterol” (HDL) and prevent cardiovascular problems including heart attacks and strokes. CETP inhibitor drugs are different than the widely used statins, which are designed ... Read More