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Prescription topical corticosteroids linked to serious adrenal suppression

Prescription topical corticosteroids used to treat swelling, redness, and itching caused by severe allergies or skin problems such as eczema and psoriasis, have been linked to adrenal suppression called hypothalamic-pituitary-adrenal (HPA) axis suppression that can lead to potentially fatal conditions such as Cushing’s syndrome. The largest incidence of adrenal suppression was seen with betamethasone propionate, which was approved in 2001 and is available in a cream, ointment or lotion. In one study, 58 percent of 60 patients with atopic dermatitis aged 1 to 12 who were treated with Diprolene AF Cream (0.05%), which contains the active ingredient betamethasone. The rate ... Read More