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cobalt 144 articles

Small-Head Metal-on-Metal Hip Implants Fail Frequently

Large-diameter metal-on-metal hips were thought to be an independent risk factor in hip failure, besides the material from which the prosthetic was made. But according to a recent study, adverse reactions to metal debris from small-headed metal-on-metal Articular Surface Replacement (ASR) hips are even more common than originally thought. In the study, 482 hips (424 patients) were reviewed. After the ASR small-diameter hip was recalled at an average of 4.9 years post-op, 379 patients (435 hips) agreed to a screening that measured cobalt and chromium in the blood. Metal-on-metal hip implants are created with a ball-and-cup design made up of a cobalt-chromium ... Read More

Metal-on-metal Hip Recipients Experience Adverse Soft-Tissue Reaction to Metal Debris, Study shows

In a study at Coxa Hospital for Joint Replacement in Finland, researchers assessed 176 patients who received metal-on-metal hip implants (203 hips) and found that 84 of those hips required revision surgery. In 87 percent of these revisions, adverse soft-tissue reaction to metal debris (ARMD) was diagnosed. Additionally, a larger femoral diameter and stem type had a higher risk of ARMD, metallosis, and device failure. Metal-on-metal hip designs, made by a number of medical device manufacturers such as Wright Medical, DePuy Orthopaedics and its parent company Johnson & Johnson, Stryker, Smith & Nephew and Zimmer Biomet Holdings, are made up of a cobalt-chromium alloy, which has been ... Read More

Plaintiffs Push to Consolidate Smith & Nephew Metal-on-Metal Hip claims in MDL

On Feb. 1, plaintiffs filed a petition asking the Judicial Panel on Multidistrict Litigation (JPML) to consider consolidating complaints against Smith & Nephew over its Birmingham Hip Resurfacing (BHR) and R3 Acetabular System devices. As many as 31 cases are still pending in 22 federal district courts, according to the petition, and dozens more are expected to flood in. Pretrial coordination before a single judge in Maryland would facilitate resolution of the claims, the plaintiffs say. In June of 2012, Smith & Nephew recalled its R3 Acetabular System, an optional metal liner component used in hip implant devices. This includes about 7,700 metal liners that ... Read More

Cobalt and Chromium Toxicity from Metal-on-Metal Hip Resulted in Neuropsychiatric Symptoms

According to a study published in January in BMC Psychiatry, an online journal of psychiatric disorders, cobalt and chromium toxicity from metal-on-metal hip implant failure resulted in neuropsychiatric complications after revision surgery. Metal-on-metal hip implants are designed using a metal ball and metal socket made of a cobalt-chromium alloy. When the parts rub together during normal use, the parts may shed metal ions, which can pollute the bloodstream and damage the surrounding tissue. The normal range occurring in a person’s system due to normal environmental exposure is 0–20 nmol/l for cobalt and 0–100 nmol/l for chromium. Nine of the 10 patients in this ... Read More

Indiana man claims DePuy Orthopaedics metal-on-metal hip implant is the source of ‘constant debilitating pain’

Just four days after a Texas jury awarded six plaintiffs a $1 billion verdict against DePuy Orthopaedics and its parent company, Johnson & Johnson related to the company’s metal-on-metal hip implant, a new lawsuit is filed about a similar case. An Indiana man filed a lawsuit against DePuy, the maker of his metal-on-metal hip implant, saying it caused him “constant debilitating pain and instability” because of the “friction wear from the movement at the joint.” He received the hip implant in 2008, but was forced to have revision surgery just six years later to fix the agonizing problems. The metal-on-metal implants have been ... Read More

Cobalt Toxicity is a Serious Risk for Metal-on-Metal Hip Patients

When Robert Peters wrote the Daily Mail for advice from Dr. Scurr about concerns with his metal-on-metal hip implants, the response seemed to only confirm his greatest fears – that his hip implants could be poisoning him. Peters’ blood was tested after his surgeon informed him of the recent reports of metal-on-metal hip failures. “Blood tests revealed I have 100 times more than normal the amount of cobalt in my blood,” Peters wrote, “as well as dangerous amounts of chromium.” Dr. Scurr explained that metal-on-metal hips are usually made of a stainless steel alloy containing cobalt and chromium, and were intended to ... Read More

Global Hip Replacement Market is on the Rise

In an industry analysis forecast report, the global hip replacement market has been estimated to expand at a compound annual growth rate of 4.1 percent between now and 2024, which is about $9.1 billion. The number of incidences of arthritis, hip fractures, and hip bone infection, which increase demand for hip replacements, as well as the development of new hip implants using new methods such as 3D printing technology are responsible for the rapid growth of the hip replacement market. Despite the positive growth, however, around 578 hip implant products were recalled from 2002 to 2013, including metal-on-metal hips, per the U.S. Food and Drug Administration ... Read More

Ten Cases Selected For MDL over Johnson & Johnson’s Metal-on-Metal Hip Implants

U.S. District Judge Ed Kinkeade, a Texas federal judge, has selected 10 cases for the next bellwether trial in the multidistrict litigation (MDL) over Johnson & Johnson’s metal-on-metal hip implants. They were selected from thousands of cases waiting their turn in the giant litigation. The judge conducted his own independent review of potential bellwether cases, all of which involve plaintiffs that claim the metal-on-metal hip design caused trillions of microscopic metal particles to shed with every step, which they say led to bone erosion, tissue damage, infection, inflammation and blood poisoning known as metallosis. The cobalt-chromium alloy socket-and-ball-head hip implant system has been ... Read More

The U.S. Department of Health and Human Services Adds Cobalt to List of Carcinogens

On Nov. 3, 2016 The U.S. Department of Health and Human Services (HHS) released the 14th Report on Carcinogens (RoC) that includes cobalt and cobalt compounds on its list of cancer-causing substances. The RoC is a public health document that is science-based and congressionally mandated, describing 248 listings of agents, substances, mixtures, and exposure circumstances that are known and confirmed carcinogens. The report advises that “intracellular release of cobalt ions from particles” is a key event related to toxicity and carcinogenicity, as seen the cases of metal-on-metal hip implant failure. Metal-on-metal hip implants are made primarily of cobalt and chromium alloy. Patients who have received this ... Read More

‘The Bone – er, Joint – Collector’ studies artificial implant technology

Steven Kurtz, biomedical engineer and director of the Implant Research Center at Drexel University, is the proud owner of an unusual collection of more than 7,000 artificial knees, hips, and other implants from around the U.S. He receives boxes of discarded devices from 15 hospitals in eight states, all in the name of making artificial implant technology better. “We study the tough things that happen to good implants,” said Kurtz. Kurtz has found that the most common reasons for the failure of joint replacement are infection, a loosening of the device, or dislocation, specifically in hip replacements. It’s less common for the ... Read More