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congenital heart disease 2 articles

Could SSRIs be contributing to an increase in birth defects?

More babies are born with birth defects in England and Wales than previously thought, according to a recent study from Queen Mary, University of London. At least 14,500 babies were born in 2009 with defects such as congenital heart disease, spina bifida and gastroschisis. That represents more than 2 percent of births, up from previous estimates of 1.3 percent. The data comes from five regional birth defect registries as well as two additional registries specific to particular conditions. The registries cover only about 28 percent of the overall population, and data from other areas beyond England and Wales is missing, ... Read More

Yeast infection treatment linked to rare set of birth defects

Long-term, high doses of Diflucan, also known as fluconazole, a medication used to treat yeast infections of the vagina, mouth, throat, esophagus and other organs, has been associated with birth defects when used by mothers during the first trimester of pregnancy, according to a drug safety communication issued by the Food and Drug Administration (FDA). Based on this information, the federal agency is downgrading the drug’s high-dose indication from a Pregnancy Category C classification to  Pregnancy Category D. Pregnancy Category D means there is positive evidence of human fetal risk based on human data, but the potential benefits from use ... Read More