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coronary artery disease 8 articles

FDA approves first dissolvable stent for coronary artery disease

The Food and Drug Administration (FDA) has approved the first stent to treat coronary artery disease that is absorbed by the body over time, offering an alternative to metallic stents that remain in the body permanently. The device, called the Absorb GT1 Bioresorbable Vascular Scaffold System (BVS), is manufactured by Abbott Laboratories. It is implanted in the artery after an angioplasty, or surgery to repair a blocked blood vessel, and is gradually absorbed by the body in about three years. The stent releases a drug called everolimus that limits the growth of scar tissue, which can narrow arteries, a condition ... Read More

Personal injury lawsuits piling up against makers of blood thinner Plavix

Personal and financial injury lawsuits involving the blood thinner Plavix are piling up in New Jersey against the drug’s makers, with 73 currently in the multidistrict litigation with at least another 14 being considered for transfer. The lawsuits allege the drug companies falsely advertised the prescription anti-clotting medication as a gentler-than-aspirin treatment designed to prevent heart attacks and strokes even though they knew the drug increased the risk for heart attacks, strokes, internal bleeding and death. Plavix, also known as clopidogrel, is manufactured and sold by Bristol-Myers Squibb and Sanofi-Aventis, and is aided by McKesson Corporation. The drug was approved ... Read More

Testosterone treatment linked to increased risk of heart attacks, strokes, death

Aggressive marketing campaigns by drug companies peddling testosterone treatments has resulted in an increasing number of men asking their doctors if they are a candidate for testosterone therapy. Low levels of testosterone, or “Low T” as the drug companies have dubbed it, can be blamed for a variety of symptoms from fatigue and low libido to muscle weakness and weight gain. But testosterone supplementation may not be the wonder therapy marketers are claiming it to be. Recent studies show that men who take the drugs are 30 percent more likely to have a heart attack, stroke, or die during a ... Read More

UFC champion says his use of testosterone replacement therapy is legal

Brazilian mixed martial artist and former Ultimate Fighting Championship (UFC) Light Heavyweight Champion Vitor Vieira Belfort is facing criticism of his use of testosterone replacement therapy. Many are attributing his string of first-round knockout wins to his use of testosterone drugs. However, Belfort claims the usage is legal and that his testosterone levels were actually low during his last fight. “I have the exams to prove that I have a disease. It’s simple,” he told MMAFighting.com. Nearly 3 percent of all men in the United States older than 40 take a prescription testosterone treatment to help boost low levels of ... Read More

Testosterone therapy linked to increased risk of heart attack, stroke, death

More and more men are using hormone treatments to up their low testosterone levels and enjoy more energy and a stronger libido as they enter midlife; however, the treatment may give them more than they bargained for. A new study of more than 8,700 older men has found that men who use a testosterone supplement were 30 percent more likely to have a stroke, heart attack or die. “Our findings raise some uncertainty regarding the potential safety of testosterone use in men,” authors of the study concluded. “It is important to inform patients that long-term risks are unknown and there ... Read More

FDA investigates life-threatening blood clots associated with leukemia chemotherapy drug

An increasing number of serious and life-threatening blood clots and severe narrowing of blood vessels (arteries and veins) in patients taking the leukemia chemotherapy drug Inclusig (Ponatinib) has prompted an investigation by the Food and Drug Administration (FDA). Data from clinical trials and adverse event reports after the drug was approved in December 2012 show that serious health problems have occurred in patients who were treated with Iclusig, including fatal heart attacks, worsening coronary artery disease, narrowing of the large arteries of the brain, severe narrowing of blood vessels in the extremities, and the need for urgent surgical procedures to ... Read More

Statins help lower stroke risk in diabetics, but can increase risk of diabetes in others

Cholesterol-lowering statin medications reduce the risk of recurrent stroke in patients who have diabetes or metabolic syndrome, a group of risk factors that occur together and increase the risk for coronary artery disease, stroke and type 2 diabetes, a new analysis indicates. The study, conducted by researchers at Vanderbilt University, is the first that focuses on the effect of statin treatment on secondary stroke prevention in people with type 2 diabetes or metabolic syndrome. The primary conclusion of the clinical trial found that the statin Lipitor (atorvastatin) reduced the risk of stroke in general. The secondary analysis assessed stroke risk ... Read More

Diabetes drugs Actos, Avandia linked to bladder cancer, heart failure

Actos (pioglitazone) may control blood sugar levels in older diabetics better than metformin, but it still carries risks that patients should weigh before taking the drugs, said a medical expert for AARP.org. Actos is a medication used to treat type 2 diabetes. Actos is similar to Avandia (rosiglitazone), and both drugs are in a class of medications known as thiazolidinediones (TZDs). Whether used alone or with other antidiabetic agents, TZDs can cause or worsen heart failure. In 2010, the Food and Drug Administration (FDA) severely restricted the use of Avandia because of the cardiovascular risk, but the agency did not ... Read More