Tagged Articles

Cytarabine 5 articles

Mylan recalls injectable cancer drugs, rheumatoid arthritis therapies

Injectable cancerĀ drugs and medications used to treat serious chronic illnesses including severe psoriasis and rheumatoid arthritis are being recalled because foreign matter was seen floating in the solutions. The recall is initiated by Mylan and includes the injectable drugs Gemcitabine, Carboplatin, Methotrexate, and Cytarabine. According to a company press release, administration of a sterile injectable that has foreign particulates has the potential of severe health consequences. Intrathecal administration could result in a life threatening adverse event or result in permanent impairment of a body function. Intravenous administration has the potential to damage and/or obstruct blood vessels which could induce emboli, ... Read More

Mylan recalls injectable cancer, psoriasis, rheumatoid arthritis drugs

Injectable drugs to treat various cancers, severeĀ psoriasis, and rheumatoid arthritis are being recalled by Mylan N.V. because particles were found floating in some retention samples during testing, posing a serious risk to patients. The Mylan recall affects Gemcitabine for injection, USP 200mg; Carboplatin Injection 10mg/mL; Methotrexate injection, USP 25mg/mL; and Cytarabine injection. Gemcitabine is a treatment for ovarian cancer, breast cancer, non-small cell lung cancer and pancreatic cancer. Carboplatin is used to treat advanced ovarian carcinoma. Methotrexate is administered intramuscularly, intravenously, intra-arterially, or intrathecally to treat certain neoplastic diseases, severe psoriasis and adult rheumatoid arthritis. If a sterile injectable product ... Read More

Hospira recalls ovarian cancer drug due to visible particles in vials

Drug company Hospira, Inc., is recalling three lots of the advanced ovarian cancer treatment Carboplatin injection because of visible particles found in samples taken from the lots during a routine inspection. The particles have been identified as Carboplatin crystals. If injected into a patient, the particles may become lodged in and obstruct blood vessels, potentially causing local infraction, thromboembolism (blood clots), and vasculitis (inflammation of blood vessels). Over time, granulomatous, or a noncancerous inflammation in the tissue, can form in the lungs. Hospira issued the updated recall notice just five months after it issued a recall notice on 19 lots ... Read More

Chemotherapy drugs recalled due to glass particles in vials

Hospira Inc. is recalling certain lots of injectable chemotherapy drugs because the vials may be contaminated with tiny particles that can be inadvertently injected into patients, which could cause serious health problems that require immediate medical intervention. The recalled drugs include Carboplatin, Cytarabine, Paclitaxel, and Methotrexate, which are distributed packaged in vials and used to treat various types of cancer. In addition, Methotrexate is also used to treat psoriasis and rheumatoid arthritis. The products were distributed nationwide. The recall affects 19 lots of the drugs and was ordered due to visible particles embedded in the glass located at the neck ... Read More