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depression 164 articles

Antipsychotics increase risk of type 2 diabetes in children

Children taking antipsychotic medication are at three times greater risk for developing type 2 diabetes compared to children taking other medications for the same disorders, according to a study published in JAMA Psychiatry. Antipsychotics include brand name drugs Abilify, Seroquel, Risperdal and Zyprexa. They are traditionally used to treat schizophrenia, however most prescriptions for the drugs are for the treatment of bipolar disorder, ADHD and mood disorders including depression. The study, conducted by researchers at Vanderbilt University in Nashville, involved tracking more than 43,000 children and youth between the ages of 6 and 24 years of age enrolled in Tennessee’s ... Read More

Louisiana files lawsuit against Adderall makers for off-label marketing

Irish drug maker Shire PLC pushed attention deficit hyperactivity disorder (ADHD) drugs for un-approved uses and collected federal Medicare reimbursement for these illegal actions, according to a lawsuit filed by the Louisiana attorney general. The lawsuit alleges that Shire promoted the ADHD drugs Adderall, Adderall XR and Vyvanse for uses that were not approved by the Food and Drug Administration (FDA) such as to treat depression and schizophrenia, and to aid in weight loss. Doctors have the discretion to write prescriptions for drugs for so-called off-label uses but pharmaceutical companies cannot market drugs for uses not approved by the FDA. ... Read More

Large study establishes link between SSRI use during pregnancy and birth defects

In December 2011, the Food and Drug Administration (FDA) recommended that health care providers not alter their current practice for treating depression in pregnant patients. The recommendation was based on a review of data that up to that point had been inconsistent on whether using antidepressants known as selective serotonin reuptake inhibitors (SSRIs) could cause harm to developing fetuses if taken by the mother during pregnancy. However, a month after the FDA’s announcement that studies had not established a link between use during pregnancy and birth defects, a large retrospective cohort study was published that strongly suggests that SSRI exposure ... Read More

SSRIs, SNRIs could ease symptoms for fibromyalgia sufferers

Antidepressants may offer relief for people who suffer with fibromyalgia. Fibromyalgia is a chronic central hypersensitivity syndrome, which occurs when the central nervous system becomes hypersensitive to different stimulus. This results in patients reporting a variety of symptoms including muscle pain, headaches, irritable bowel syndrome and chronic fatigue. Studies suggest that central hypersensitivity is mainly caused by an imbalance of neurotransmitters such as serotonin and norepinephrine, which work to keep pain sensation and mood in balance. When levels of serotonin or norepinephrine are out of balance, which occurs with fibromyalgia and depression, the brain cannot properly process pain signals, exaggerating one’s ... Read More

Study finds placebo treats symptoms almost as well as antidepressants

A new study shows that placebos may be just as effective as antidepressants for treating depression, suggesting that many people may not need to take the drugs, exposing themselves to potentially dangerous side effects. The study, conducted by researchers at the University of Dundee, Scotland, observed patients in a primary care setting who were either prescribed selective serotonin reuptake inhibitors (SSRIs), tricylic, or placebo. After six to eight weeks, researchers followed up with patients and asked if their depression symptoms were improved. Fifty-six percent of patients on SSRIs reported improvement compared to 43 percent on placebo. Sixty percent of patients ... Read More

SSRI use during fertility treatments shows little benefit to mother or fetus

Depressed women taking selective serotonin reuptake inhibitors (SSRIs) who are also undergoing infertility treatment may be more likely not to conceive, to suffer complications with pregnancy, and to have a baby with birth defects, a new meta-analysis shows. Women undergoing infertility treatments often battle depression. A study published in Medical News Today investigated depressed women undergoing infertility treatment and the risks to their fetuses while taking SSRIs. The new meta-analysis took a different approach than past studies, investigating the safety and efficacy of infertile women being treated with SSRIs. Researchers culled through studies and found that SSRI is associated with lowered ... Read More

Study: Pregnant women who get the flu at greater risk of having a child with bipolar disorder

A new warning for expectant women – a new study has found that pregnant women who get the flu have a four-time greater risk of having a child with bipolar disorder. Bipolar disorder is a psychiatric diagnosis in which people experience episodes of mania typically balanced with episodes of depression. The disorder is most commonly diagnosed in the teens and 20s. The study, conducted by researchers at Columbia University Medical Center in New York City, involved more than 900 U.S. children, 92 of whom had been diagnosed with bipolar disorder. After culling through the data, researchers discovered that mothers who ... Read More

Judge to decide whether head trauma lawsuits against NFL will go to trial

The National Football League is facing more than 200 lawsuits filed on behalf of more than 4,300 former players alleging that the league “ignored, minimized, disputed, and actively suppressed” its awareness that repeated concussions were associated with a degenerative brain disease known as chronic traumatic encephalopathy (CTE). A Philadelphia judge has been charged with deciding whether the lawsuits will go to trial or be settled by arbitration. If the claims constitute a labor dispute, which the league is banking on, then they would be settled by an arbitrator. The former players, however, say the claims go beyond that scope and ... Read More

New study confirms even one concussion could lead to lasting brain damage

A report published in the online journal Radiology reveals the results of a new study confirming even a single concussion can have a lasting impact on the brain. Researchers believe this is due to a decrease in brain volume, which can result from a mild traumatic brain injury like a concussion. A news release from the Radiological Society of North America notes that Centers for Disease Control and Prevention (CDC) statistics indicate 1.7 million people in the United States each year sustain a traumatic brain injury (TBI). A TBI is the result of sudden trauma to the brain. A concussion ... Read More

New warnings added to Chantix label include cardiovascular events, psychiatric symptoms

The safety label for the smoking cessation drug Chantix (varenicline) has been updated to include new warnings about cardiovascular risks. The warning is based on a large, combined analysis of clinical trials that showed more serious cardiovascular events occurred in people who were taking Chantix. The report was released late last year by the Food and Drug Administration (FDA), which added that the risks were uncommon in both the Chantix and placebo groups, and that it is difficult to determine whether the excess risk of serious heart events among patients taking Chantix was due to the drug or simply chance. ... Read More