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DePuy Orthopaedics 271 articles

Patients with metal-on-metal hip exhibit increase in cobalt and chromium levels

Just two years ago, a five-year follow-up was performed on 52 randomized patients that had received either a metal-on-metal hip or metal-on-polyethylene hip implant. Tests confirmed an alarming 10- to 20-fold increase in cobalt and chromium levels in the systems of the patients who received the metal-on-metal hip implant. Most hip implants last for 20 years or more. However, patients are reporting metal hip implants like the ASR metal-on-metal hip implants made by DePuy Orthopaedics, a subsidiary of Johnson & Johnson, are failing in only five years Other metal-on-metal hip implant makers are Smith & Nephew, Wright Medical, Zimmer Biomet Holdings and Stryker. All  have faced an onslaught ... Read More

Number of hip implant revision surgeries on the rise; physicians link osteolysis to metal components

For the past 20 years, researchers at Rush University Medical Center have been studying the durability of hip implants, following the results from 204 total hip replacements performed at the center. The patients were aged anywhere from 20 years old to 84 years old. During the course of the study, the number of revision surgeries had increased because of osteolysis, which is bone resorption. Doctors explain osteolysis is how the body reacts to metal debris, which may be created by wear and corrosion of metal-on-metal hip implants. “With time, the number of repeat surgeries due to wear and osteolysis has increased, as have the numbers of ... Read More

New York Times labels J&J ASR Metal-on-Metal Hips “One of the Biggest Medical Device Failures in Recent Decades”

Johnson & Johnson and its subsidiary, DePuy Orthopaedics, has been dealing with thousands of lawsuits regarding its metal-on-metal ASR hip implant, which, according to the New York Times, has been dubbed “one of the biggest medical device failures in recent decades.” The article also points out evidence presented in the trials that alleges J&J knew of design problems with the implant long before the company decided to recall it. About 93,000 patients worldwide have received an ASR hip, one third of those in the U.S. After gathering the number of hip device replacements, DePuy estimated that nearly 40 percent of patients who received the ASR metal-on-metal hip ... Read More

Man diagnosed with Cobalt Poisoning After Receiving Metal Hip Implant

A patient with severe heart failure was referred to the Marburg University clinic in Germany in 2012. A possible cause was coronary artery disease, but after further examinations, the medical team ruled it out. However, some of the medics working on the case noticed a few notable similarities between the patient’s symptoms and the symptoms of a patient on House, a TV series in which British actor Hugh Laurie plays the lead character, Gregory House, M.D. On the TV show, a patient was experiencing strikingly similar symptoms and was diagnosed as having cobalt poisoning, which was caused by the debris shed ... Read More

As Many as Half a Million Patients at Risk from Metal-on-Metal Hip Implants

The U.S. Food and Drug Administration (FDA) spent two days convening a meeting to address the issues with the metal-on-metal hip implants, and for good reason: the metal-on-metal designs, such as the ones made by DePuy Orthopaedics, a subsidiary of Johnson & Johnson; Zimmer Holdings Inc. and Wright Medical Group, have been linked to injures, muscle and tissue damage, bone damage, loosening, and more. As many as half a million recipients of the metal-on-metal hip implants could be at risk. The metal-on-metal hip implant devices were recommended for patients with a more active lifestyle, based on claims the all-metal system was a better ... Read More

FDA Warns of Medical Effects that Can Occur with Metal-on-Metal Hip Implants

In February, the U.S. Food and Drug Administration (FDA) provided information to the public advising of potential medical effects that can occur with metal-on-metal hip implants. Makers of such metal-on-metal implants, such as Johnson & Johnson and its subsidiary DePuy Orthopeadics; Smith & Nephew, and Wright Medical have been swamped with lawsuits for injuries and negative health effects allegedly caused by the devices. The FDA points out that metal-on-metal hip implants have the same adverse effects as any other type of hip implant such as loosening, infection, bone loss, fracture of the device or bone, and joint dislocation. But the FDA openly warns of the additional ... Read More

Metal-on-Metal Hip Implants Referred to as ‘a large uncontrolled experiment’ by BMJ Publication

According to BMJ Magazine, a leading publication about medical news, metal-on-metal hip implants are basically “large uncontrolled experiment” because the patients who received them were kept in the dark about the details and risks of this type of hip implant device. With a metal-on-metal hip device, such as the models made by Johnson & Johnson’s subsidiary DePuy Orthopaedics, and Smith & Nephew, there is great risk in a few areas. First, the large-diameter ball-and-cup designs tend to wear out faster and become dislocated. In fact, the average failure rate at the seven year mark for metal-on-metal implants is 13.6 percent, which is ... Read More

ASR Metal Hip Implant Has Failure Rate of Up to 50 percent Within Six Years

According to an article published by BMJ, ASR metal-on-metal hip implants such as the designs made by DePuy Orthopaedics, a subsidiary of Johnson & Johnson, are shown to have a failure rate of up to 50 percent within six years. “Metal on metal joints are designed to harness naturally occurring lubricating fluids from the native hip,” the article reads. “As wear debris is generated, hip joints become filled with high concentrations of chromium and cobalt. This leads to a chain of events culminating in extensive soft tissue necrosis and disruption of bone. The metallic ions then diffuse into the blood stream.” But the ... Read More

Metal-on-Metal Hip Implants Causing Metal Poisoning and Metallosis

Metal-on-metal hip implants such as the DePuy ASR that uses a metal ball and cup or designs such as the Stryker Rejuvenate and ABG II  that uses a metal neck and stem have caused many patients to have adverse effects because of the corrosion of the metal components within the body, resulting in thousands of lawsuits. All of these components are made of cobalt and chromium which, upon corrosion and wear-down, can flake metal particles into the body and cause metallosis. The body naturally stores a certain level of chromium and cobalt, which promotes healthy cellular function. However, when these metal components from a hip ... Read More

New 3D-printed Titanium Hip Implant Unveiled

Smith & Nephew, a global medical technology business, has creatively designed a titanium hip implant using 3-D technology. The new REDAPT™ Revision Acetabular Fully Porous Cup with CONCELOC™ Technology is designed to be used in revision cases where implant fixation and stability is made more difficult by compromised bone. A 3-D process produces an entirely porous implant that allows ingrowth and mimics the structure of cancellous bone. The stability of the implant can be strengthened using new variable-angle locking screws, and minimizes micromotion following surgery. The FDA has cleared the use of REDAPT Cup in November 2015, but was just officially ... Read More