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diabetes 222 articles

Studies indicate Lipitor is linked to development of Type 2 diabetes

High cholesterol is a big problem in our country and Lipitor, or its generic counterpart atorvastatin, is one of the leading prescription drugs used to help combat it. However, studies show that it may cause an increased chance of the patient developing diabetes. The study suggests that the risk is greatly increased for those who already have risk factors of Type 2 diabetes, such as: excess weight, high blood sugar, high blood pressure and elevated triglycerides. Head researcher Dr. David D. Waters, of the University of California at San Francisco, told Reuters Health in an email that those four factors appear “very ... Read More

Women less likely to tolerate statin side effects

Researchers are suggesting that gender-based therapy would better suit women with diabetes because they are less likely to stick to treatment and have a greater risk of heart disease than men. One reason why diabetic women, in general, fare worse than men with diabetes is because they are less likely to follow through with treatment goals – such a lowering their LDL – or “bad” – cholesterol levels. They are also at greater risk of developing cardiovascular disease related to their diabetes, often because they have a more difficult time lowering their cholesterol. One likely reason why women do not ... Read More

More drugs in development to treat ailments of an increasing aging population

Americans are living longer and as a result, the number of people 65 years of age and older with serious chronic conditions is also increasing. Pharmaceutical companies are rushing to cash in by developing drugs to treat the nearly 50 million Medicare beneficiaries who are battling conditions such as diabetes, high cholesterol, high blood pressure, and osteoarthritis. Currently, about 435 drugs primarily targeting seniors are either in clinical trials or under review by the Food and Drug Administration (FDA), according to a report by the Pharmaceutical Research and Manufacturers of America. Among them, 110 are designed to treat diabetes, 68 ... Read More

Number of diabetics continues to escalate year after year

The rate of diabetes and pre-diabetes in the United States continues to rise dramatically, so much so that the Centers for Disease Control and Prevention (CDC) warns one in every three Americans will have the condition by 2050. The new National Diabetes Statistics Report estimates that from 2010 to 2012, the number of adults with diabetes jumped from 26 million to nearly 30 million, and that a quarter of those individuals don’t know they have the disease. Uncontrolled diabetes can cause serious complications including heart disease, kidney disease, blindness, and amputations due to neuropathy. Also alarming is that another 86 ... Read More

FDA lifts clinical hold on experimental pancreatic cancer treatment

The Food and Drug Administration (FDA) has removed a clinical hold on patient enrollment and dosing of PEGPH20 in a Phase 2 trial evaluating the drug in patients with pancreatic cancer. The study will resume under a revised protocol. In April, the FDA placed the clinical hold following Halozyme Therapeutics’ decision to temporarily halt enrollment and dosing of the drug in order assess thromboembolic event risks in patients treated with the drug. “Pancreatic cancer has one of the lowest survival rates of any cancer,” Dr. Helen Torley, President and CEO of Halozyme, said at the time. “We remain committed to ... Read More

FDA approves new ‘high-intensity’ sugar substitute

A new zero-calorie sweetener will soon hit store shelves, giving consumers more sugar substitute options to sweeten or add flavor to their foods, the Food and Drug Administration (FDA) announced. The new sweetener is called advatame, but does not yet have an official brand name. Advatame, along with other marketed sugar substitutes, are called high-intensity sweeteners “because small amounts pack a large punch when it comes to sweetness,” says Captain Andrew Zajac, U.S. Public Health Service (USPHS) director of the Division of Petition Review at the Food and Drug Administration (FDA). Unlike sweeteners like sugar, honey or molasses, high-intensity sweeteners ... Read More

Death rate, incidents of pancreatic cancer continue to climb; diabetics in high risk group

Death rates from pancreatic cancer as well as incidents of the disease continue to rise in both men and women, according to a new study published in the journal Annals of Oncology. “The increased death rate is cause for concern because the prognosis for this tumor is bleak, with less than five percent of pancreatic cancer patients surviving for five years after diagnosis,” said Dr. Carlo La Vecchia, lead author of the study. Pancreatic cancer is typically diagnosed in an advanced stage, which makes it one of the more deadly forms of the disease. There are also no promising treatments ... Read More

FDA warns manufacturer, advises public not to use GenStrip diabetes test strips

The Food and Drug Administration (FDA) warned a manufacturer of diabetes test strips about manufacturing violations and issued a safety communication urging consumers and health care professionals not to use the company’s products. GenStrip Blood Glucose Test Strips, sold by Shasta Technologies LLC, are used with the LifeScan OneTouch family of glucose meters, such as the Ultra, Ultra 2, and Ultra Mini. During a recent inspection of Shasta Technologies LLC, the FDA found extensive violations of federal regulations that put into question the quality of the products in the manufacturing of GenStrip Test Strips. These regulations, called quality system regulations, require ... Read More

Large analysis links diabetes to increased risk of pancreatic cancer

Diabetics are twice as likely to develop pancreatic cancer compared to non-diabetics, according to a new meta-analysis of 88 previous studies. Diabetes has long been associated with pancreatic cancer, however researchers could not pin down if the diabetes caused the cancer, or the cancer contributed to the diabetes. This new analysis suggests that for some individuals, their pancreatic cancer may trigger diabetes. Researchers also found that diabetics had a seven-fold increased risk of being diagnosed with pancreatic cancer within the first year of being diagnosed with diabetes. “Studies have demonstrated that pancreatic cancer can produce certain substances that influence the way ... Read More

Cases of diabetes on the rise in the United States

The number of Americans with diabetes has nearly doubled in the past 20 years, paralleling the country’s growing obesity epidemic. Experts say if the trend continues, the number of Americans with diabetes will reach 44 million in the next 20 years. The study was published this week in the Annals of Internal Medicine. Researchers say the increase could be attributed to better screening tools, such as the hemoglobin A1c diagnostic test. However, researchers say the number of estimated undiagnosed cases in the past two decades has remained flat at about 2.3 million. Type 2 diabetes is by far the most ... Read More