Tagged Articles

dosing 2 articles

FDA needs more information on dosing, side effects for new antipsychotic drug

The Food and Drug Administration (FDA) says it needs more information about dosing and side effects for a new antipsychotic medication before it will decide whether to approve the drug. The drug candidate cariprazine, made by Forest Laboratories Inc., is designed to treat Bipolar I disorder, a type of manic-depressive illness characterized by unusual shifts in a person’s mood that can interfere with daily activities. It is also designed to treat schizophrenia, a conditions with symptoms such as hallucinations, delusions and social withdrawal. The drug is also being tested, though approval not yet sought, as a potential adjunct in treatment-resistant ... Read More

Genetic test helps determine safer dosing of blood thinner

A genetic test is being used to determine the proper dosage of the blood thinner warfarin in patients at the University of Illinois Hospital & Health Sciences System. The medical center is one of the first in the nation to use genetic information in order to cater to individual patients’ specific dosages of a drug that ranks among the leading causes of drug-related adverse events. Warfarin is an anticoagulant that has been on the market for more than 50 years. It is used to treat deep vein thrombosis and pulmonary embolism and to prevent stroke in patients with atrial fibrillation ... Read More