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estradiol 3 articles

Estrogen patches carry new warnings for cancer, cardiovascular disease, dementia

Estraderm transdermal system used to treat symptoms of menopause has a new black box warning added to its safety label. The new label warns of endometrial cancer, cardiovascular disorders, breast cancer, and probable dementia. Black box warnings, or boxed warnings, are the strongest warning that the Food and Drug Administration (FDA) requires, and signifies that medical studies indicate that the drug carries a significant risk of serious or even life-threatening adverse effects. The Estraderm (estradiol) transdermal system is a patch that is placed on the trunk of the body to deliver the hormone estrogen to treat menopause symptoms including hot flashes, vaginal dryness ... Read More

Chinese parents say tainted milk powder caused premature puberty

It seems China can’t stop producing tainted products. This time, pediatricians in the central province of Hubei are expressing concern over premature development of breasts in three infant girls, and are suggesting that milk powder manufactured by Synutra International is the culprit. The infants who were affected had levels of estradiol and prolactin, hormones that stimulate the production of breast milk, that were as high as those in adult women. One father in Beijing said his daughter not only had grown breasts but was also releasing vaginal discharge. A Health Ministry investigation of 73 baby-milk products manufactured by Synutra as ... Read More

Women using Evamist hormone spray should avoid children, pets

Women who use Evamist, an estrogen spray applied to the skin to treat symptoms of menopause, should not come in contact with children or pets because children and pets may experience adverse effects such as nipple swelling from unintentional exposure, according to a new Food and Drug Administration (FDA) consumer update. Evamist contains the estrogen hormone estradiol. It is sprayed inside the forearm between the elbow and the wrist. The FDA is currently reviewing reports of adverse events in children and pets who were unintentionally exposed to Evamist, including reports of premature puberty, nipple swelling and breast development in girls ... Read More