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ethinyl estradiol 38 articles

Contraindication added to ethinyl estradiol drugs

A new contraindication is being added to birth control pills and other treatments containing the hormone ethinyl estradiol regarding the use of these drugs with certain hepatitis C (HCV) drug combinations. Specifically, using HCV drug combinations containing ombitasvir, partiaprevir/ritonavir, with or without dasabuvir is contraindicated because there is a risk for liver enzyme elevations. This was observed in clinical trials with women using ethinyl estradiol-containing medications, such as combined oral contraceptives. These women were significantly more likely to have ALT elevations that in some cases was greater than 20 times the upper limit of normal. ALT, or alanine transaminase, are ... Read More

Recent use of high-dose estrogen birth control pills linked to increased risk of breast cancer

Women who recently took a certain formulation of birth control pills may have an increased risk of breast cancer, according to a new study published in the journal Cancer Research. Researchers at the Fred Hutchinson Cancer Research Center and the University of Washington in Seattle reviewed health records for oral contraceptive usage among more than 1,100 women with beast cancer, most of whom were diagnosed with the disease in their 40s. Researchers divided the birth control pills into three categories – those with a low level of synthetic estrogen (about 20 micrograms of ethinyl estradiol), those with a moderate level of ... Read More

Merck reaches $100 million settlement in NuvaRing side effects lawsuits

A $100 million settlement involving life threatening side effects from Merck’s NuvaRing birth control device will stand now that a vast majority of claimants have agreed to the terms of the settlement. The settlement was approved by U.S. District Judge Rodney W. Sippel of St. Louis in February; however, Merck had the opportunity to abandon the deal if it did not get at least 95 percent of the claimants to sign off on the terms. About 3,800 people will share in the settlement. NuvaRing was approved as a contraceptive device in 2002 by the Food and Drug Administration (FDA). It ... Read More

New blood clot warning with NuvaRing contraceptive device

A new warning has been added to the safety label of the NuvaRing contraceptive vaginal ring, alerting health care providers and women that the birth control method should be discontinued if symptoms of blood clots are experienced. Symptoms of blood clots include chest pain; shortness of breath; upper body discomfort such as in the arms, back, neck or jaw; redness, warmth or swelling in the lower leg; headaches; speech changes; paralysis, dizziness; or trouble speaking. “Stop NuvaRing use if an arterial thrombotic or venous thromboembolic event (VTE) occurs,” the warning reads. “Stop NuvaRing use if there is unexplained loss of ... Read More

Estarylla birth control pills recalled due to packaging flaw

One lot of Estarylla birth control pills made by Sandoz is being recalled because a customer found an inactive tablet in a row of active tablets in one pack. The pill packs include blue tablets, or active pills, that contain a combination of the hormones norgestimate and ethinyl estradiol that work to stop ovulation and thus prevent pregnancy. The green pills, sometimes called placebos or sugar pills, contain only inactive ingredients. Sandoz is not aware of any adverse events associated with the recall. The company conducted an internal medical assessment and concluded that the likelihood of adverse health effects is ... Read More

FDA approves new extended regime oral contraceptive

Quartette, a new generation of extended regime oral contraceptives, has been approved by the Food and Drug Administration (FDA), Teva Pharmaceuticals announced. The combination levonorgestral/ethinyl estradiol and ethinyl estradiol tablets are designed to minimize breakthrough bleeding between scheduled periods. Breakthrough bleeding is a common side effect with extended regime birth control pills, especially during the first few months, and one of the main reasons why women give up on the pills. The estrogen in Quartette increases at specific points and provides four short, light periods a year. FDA approval is based on a series of clinical trials involving more than ... Read More

Bayer’s profits take a hit due to Yaz lawsuits

Lawsuits against the birth control pill Yaz took a huge bite out of Bayer’s fourth quarter profits. The company reported net profits of $490 million, a far cry from the $519 million it brought in last year. The company cited charges due to Yaz lawsuits in the United States as the culprit for lagging profits. The lawsuits claim that Yaz causes blood clots that can lead to sometimes fatal heart attacks, strokes and pulmonary embolisms. Yaz is Bayer’s once mega-popular birth control pill. It contains the hormones drospirenone and ethinyl estradiol. While all combination oral contraceptives can increase a woman’s ... Read More

French, Canadian drug regulators question deaths tied to acne pill

French drug regulators are suspending the sale of Bayer Healthcare’s acne pill Diane 35 (sold in some countries as Dianette) after four deaths in the past 25 years were linked to the hormone pill. France’s ANSM said the deaths were due to blood clots, and that the agency was also concerned about three deaths from other health issues in women who were using Diane 35. Canadian officials are also investigating 11 deaths that may be linked to Diane 35, including four teenagers. Diane 35 is designed to treat acne in women; however, some doctors prescribe the pill as birth control. ... Read More

Bayer introduces new hormone-releasing IUD Skyla

The Food and Drug Administration (FDA) has approved a new contraceptive device  made by Bayer HealthCare Pharmaceuticals. Skyla, an intrauterine device (IUD) that releases the hormone levonorgestrel, is placed in the uterus to prevent pregnancy for up to three years. Skyla was found to be more than 99 percent effective at preventing pregnancy and is an attractive contraception alternative to the birth control pill, which must be taken daily. The device is a small, flexible plastic T-shaped device containing 13.5 mg of the progestin hormone levonorgestrel. Because Skyla slowly releases levonorgestrel into the uterus, only small amounts of the hormone ... Read More

Ortho Evra birth control patch now warns of death, permanent disability from blood clots

Stronger warnings have been placed on packages of the Ortho Evra birth control patch, informing users that studies suggest women who use the patch are at greater risk of developing potentially life-threatening blood clots than women who use some oral contraceptives. Birth control pills with the combined hormones estrogen and progestin carry a risk for blood clots. Ortho Evra is a combined hormone contraceptive, containing the progestin norelgestromin and the estrogen ethinyl estradiol. The patch is a thin, matrix-type transdermal patch that is applied to the skin and gradually releases the active ingredients to stop ovulation in order to prevent ... Read More