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gastroparesis 42 articles

Why did FDA take so long to place black box warning on Reglan?

In the February 1996 issue of the drug newsletter Worst Pills, Best Pills News, a story was published by the Health Research Group of Public Citizen warning that a drug commonly prescribed for heartburn and slow emptying of the stomach contents, a condition known as gastroparesis, could cause a serious movement disorder known as Tardive Dyskinesia. The condition could cause permanent disability in users, according to the report. However, it took more than a decade for the Food and Drug Administration (FDA) to place a black box warning on the medication, Reglan. A black box warning is the strongest warning ... Read More

Study may lead to new treatment of gastroparesis

Very low doses of inhaled carbon monoxide has been shown to reverse a serious digestive condition in diabetic mice, a finding that could give hope to millions of sufferers of diabetic gastroparesis. The findings are based on a study conducted by researchers with the Mayo Clinic and presented at last year’s Digestive Disease Week gathering. “This is a significant finding, as it shows that loss of the enzyme that makes carbon monoxide is the actor in this process and that it provides us with a clear approach toward a possible new therapy for this condition,” says Gianrico Farrugia, M.D., Mayo ... Read More

Ruling: patients may sue generic drug makers under state law

The U.S. Fifth Circuit Court of Appeals has found in favor with a lower court that patients may sue generic drug makers under state law for failing to provide adequate warnings about potential side effects with their drugs. The ruling extends a 2009 U.S. Supreme Court ruling governing makers of name-brand drugs. The issue of whether generic drug companies should be held liable for not adequately warning consumers has divided several district courts, which can increase the odds of a Supreme Court review in the future, according to U.S. Circuit Judge Patrick Higginbotham. The Fifth Circuit upheld a lower court ... Read More

Gastroparesis organization raises awareness through video

The Gastroparesis Awareness Campaign Organization has released a video to help raise awareness of the seriousness of the condition in which the stomach takes too long to digest food. The video, called The Faces of Gastroparesis 2009, can be seen on YouTube, and here: People of all ages, shapes and sizes suffer from gastroparesis. The National Institutes of Health estimates as many as 10 million people are living with gastroparesis. Because of the lack of medical education and improper diagnosis, many more may be suffering in silence. Symptoms include abdominal cramps, nausea and vomiting and can result in dehydration, electrolyte ... Read More

Pacemaker gives hope to sufferer of gastroparesis

Thirty-two-year-old Shimmi Munshi would get sick up to 50 times a day over a four-year period, but doctors were at a loss as to why. She was put on feeding tubes and medication, but the treatments did little to help her. She became sicker and weaker. It wasn’t until the young woman scoured the Internet that she some answers. She immediately diagnosed herself with gastroparesis, or paralysis of the stomach. And found a treatment that would help her live a normal life.  Gastroparesis is a serious condition in which food takes too long to move through the stomach. It can ... Read More

New medical center to focus on gastrointestinal disorders

A new medical center specializing in gastrointestinal disorders is opening in El Paso, Texas, offering hope to patients throughout the country who suffer from debilitating symptoms. The new center is a collaborative effort between the University Medical Center of El Paso and Texas Tech University Health Sciences Center Paul L. Foster School of Medicine. Called the Center for Gastrointestinal Motility and Functional Bowel Disorders, the center will diagnose and treat people who have problems digesting food. Patients who suffer from regular vomiting, stomach pain or trouble swallowing are usually given diagnostic tests such as endoscopies, biopsies and CT scans. Some ... Read More

Woman suffers from movement disorder after getting flu shot

UPDATE: It has been brought to our attention that the young woman featured in this post may have been misdiagnosed. There is some controversy about whether she was suffering from dystonia, her illness was psychogenic, or it was a hoax. We are currently researching the matter and will provide an updated post as soon as possible. A YouTube video originally posted with this story is no longer available. Dystonia is a neurological movement disorder that can be disabling. Those who suffer from the condition experience muscle contractions that cause twisting and repetitive movements or abnormal postures. The causes are not ... Read More

Women suffering from movement disorder sues Reglan maker Wyeth

Elizabeth Conte was prescribed Reglan, a brand-name of metoclopramide used to treat gastrointestinal conditions such as heartburn, GERD and gastroparesis. For four years she took the medication, unaware that she was slowly developing a debilitating and incurable movement disorder known as Tardive Dyskinesia. What she soon found out is that her involuntary head jerks and facial twitches were caused by long-term use of metoclopramide. More and more cases of consumers taking metoclopramide and subsequently developing Tardive Dyskinesia were reported to the Food and Drug Administration (FDA), and by early 2009, the agency had ordered a black box warning be placed ... Read More

Anti-nausea drugs carry black box warnings

Patients who suffer from nausea and vomiting are often given medication to stop their symptoms. But many of those drugs carry serious side effects that have earned them black box warnings from the Food and Drug Administration (FDA). A black box warning indicates that use of the drug carries a significant risk of serious or life-threatening adverse effects. Last month, the FDA issued a black box warning on the injectable form of promethazine hydrochloride. Promethazine hydrochloride, once sold under the now-discontinued brand name Phenergan, is available in generic formulations in the form of tablets, liquid, rectal suppository, intravenous injection and ... Read More

Pregnant women should weigh risks of morning sickness medications

Metoclopramide, known in the U.S. by the brand names Reglan and Metozolv, is a commonly prescribed medication used in the treatment of serious gastrointestional disorders, such as GERD and gastroparesis. Earlier this year, a study suggested that the medication may also help women suffering from morning sickness, in particular a severe form marked by serious vomiting called hyperemesis gravidarum. The study, which involved more than 80,000 births to Israeli women, found that women who took the medication while pregnant did not raise the risk of harming their unborn child. This is promising news, considering there are no FDA-approved drugs to ... Read More