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gastroschisis 4 articles

Life-threatening birth defect linked to opioid use

A potentially deadly birth defect in which a baby’s abdomen doesn’t develop properly and his intestines poke outside the body may be tied to the mother’s opioid use during pregnancy, according to an analysis published by the Centers for Disease Control and Prevention (CDC). The defect, called gastroschisis, occurs early in pregnancy. Researchers don’t know what it is about opioids that may cause this defect, just that there is “a higher prevalence (of the defect) in areas where opioid prescription rates were high,” the report said. Gastroschisis is more often seen in teen mothers and mothers who drink and smoke. ... Read More

Could SSRIs be contributing to an increase in birth defects?

More babies are born with birth defects in England and Wales than previously thought, according to a recent study from Queen Mary, University of London. At least 14,500 babies were born in 2009 with defects such as congenital heart disease, spina bifida and gastroschisis. That represents more than 2 percent of births, up from previous estimates of 1.3 percent. The data comes from five regional birth defect registries as well as two additional registries specific to particular conditions. The registries cover only about 28 percent of the overall population, and data from other areas beyond England and Wales is missing, ... Read More

Parents file birth defects lawsuit against makers of Zoloft

Parents of children with birth defects who were exposed to the antidepressant Zoloft during gestation are suing the drug maker claiming the mothers took the antidepressant only because they believed it to be a safe medication to take during pregnancy. The plaintiffs allege that their children were born with varying birth defects including heart defects, neural tube defects, gastroschisis, omphalocele, craniosynostosis, cleft lip, club foot, anal atresia, and limb reduction defects. They blame the drug. “Pfizer knew or should have known that Zoloft crosses the placenta, which could have important implications for the developing fetus,” the lawsuit states. The plaintiffs ... Read More

Darvon, Darvocet also increase risk for birth defects

The newly banned drugs Darvon and Darvocet are among a type of drug that puts the unborn babies of women who use the drugs just before or during pregnancy at risk for birth defects, in particular heart defects, according to an ongoing, population-based study conducted by the Centers for Disease Control (CDC). The study focused on use of opioids, or potent prescription painkillers that include propoxyphene (Darvon and Darcocet), oxycodone, morphine, tramadol, methadone, and fentanyl. Researchers looked at opioid exposure in mothers from three months before conception through the end of pregnancy. They found that women who received opioid treatment ... Read More