Tagged Articles

heart problems 50 articles

FDA approves new diet pill Contrave

A new prescription diet pill has been given clearance by the Food and Drug Administration (FDA) for marketing in the United States. Contrave, made by Orexigen Therapeutics, is a combination of bupropion, an antidepressant that is also used for smoking cessation, and naltrexone, a drug used to treat drug and alcohol dependence. Contrave is approved for overweight or obese patients with a body mass index (BMI) of 30 or higher, as well as people with a BMI of 27 or higher with at least one other health issue such as diabetes. Patients treated with Contrave lost an average of 4.2 ... Read More

New testosterone replacement capsule fares well in clinical trials

Clinical trials for Clarus Therapeutic’s new testosterone replacement treatment Rextoro show the drug is comparable to other testosterone therapies and, if approved by the Food and Drug Administration (FDA), could provide patients with yet another treatment option to boost the amount of the male hormone in their systems. Rextoro is a softgel capsule that contains a testosterone prodrug, testosterone undecanoate, or TU. It is formulated to foster absorption via the intestinal lymphatic pathway. After oral TU is absorbed, natural enzymes in the body cause testosterone to be released from the prodrug. “This proprietary formulation enables us to increase the amount ... Read More

Testosterone levels tend to fluctuate significantly in younger men but remain more constant in older men

Most schools of thought suggest that measuring testosterone levels in men can be tricky because the hormone levels vary from day to day as well as hour to hour. However, a new study finds that only young men experience statistically and clinically significant fluctuations in testosterone levels. Researchers studied records of more than 2,500 men ages 26 to 84 who had their testosterone levels checked at an erectile dysfunction clinic. The men were sorted into five age groups, beginning with 26- to 39-year-olds. Each of those groups were divided into sub-groups depending on the time of day their testosterone was ... Read More

Fresenius fighting request to produce adverse event reports related to GranuFlo, NaturLyte

Fresenius Medical Care is fighting a request by plaintiffs for the dialysis products and services provider to produce hard copies of adverse event reports involving patients because it would require the company to sift through records at 2,100 clinics with a client base of 170,000 patients in 2013. The motion was filed in federal multidistrict litigation in Massachusetts alleging Fresenius withheld information that its dialysis concentrates GranuFlo and NaturaLyte could cause patients to suffer heart problems and deaths. GranuFlo and NaturaLyte are solutions used to maintain proper acid balance in patients’ blood when they undergo hemodialysis for the treatment of ... Read More

FDA sends strong warning against using lidocaine anesthetic for teething pain in infants, children

Prescription oral viscous lidocaine 2% anesthetic solution should not be used to treat teething pain in infants or children because it can cause serious injuries, including death, the Food and Drug Administration (FDA) warned. The agency is ordering a new black box warning be added to the safety label of lidocaine products to alert health care professionals, providers and caregivers of this risk. Topical pain relieves and medications that are rubbed on the gums to relieve pain are not necessary or even useful because they wash off the baby’s mouth within minutes, the agency warned. When too much viscous lidocaine is ... Read More

Wrongful death lawsuit filed against dialysis provider Fresenius Medical Care

Immediately after Beverly Stockton received hemodialysis treatment at Fresenius Medical Care in Charleston, W.Va., she suffered cardiac arrest and died. Her husband James Stockton is suing Fresenius, the largest provider of dialysis products and services, for her wrongful death. James’ lawsuit alleges that his wife was given the dialysis concentrate GranuFlo, which had confusing dosing instructions that caused his wife to receive toxic levels of bicarbonate, an ingredient in GranuFlo. Elevated bicarbonate can cause heart problems including sudden cardiac arrest. The complaint claims that long before his wife received her fatal dose of GranuFlo, Fresenius executives had received, but disregarded, ... Read More

Many preteens with high cholesterol at risk for heart problems later in life

As many as one-third of all preteens may have borderline or high cholesterol, putting them at risk of heart problems later in life, a new study suggests. The study involved 13,000 Texas preteens and will be presented at the American College of Cardiology conference this week. Researchers say it sheds light on the growing problem of high cholesterol in children and whether more can be done to prevent long-term consequences as these children age. Recently, the National Heart, Lung and Blood Institute announced new guidelines calling for every child to have a cholesterol test sometime between ages 9 and 11. ... Read More

Fresenius faces false advertising lawsuit over dialysis products GranuFlo, NaturaLyte

Fresenius Medical Care, the world’s largest provider of dialysis products and services, faces a false advertising lawsuit alleging improper instructions on its dialysis concentrates GranuFlo and NaturaLyte caused serious adverse events including heart attack, stroke and death. The lawsuit claims that Fresenius knowingly concealed the serious health risks associated with the products. Plaintiffs allege Fresenius continued to market and profit from sales of GranuFlo and NaturaLyte even after it learned that the product had been associated with heart problems including cardiac arrhythmia and sudden cardiac arrest. Fresenius also faces hundreds of wrongful death and personal injury lawsuits stemming from improper ... Read More

Statins may reduce risk of heart attack, stroke but do not prevent death

People older than age 65 who are at risk for heart disease but have no known heart problems may reduce their risk of heart attack and stroke by taking cholesterol-lowering statins. However, the medication may not prevent them from dying from cardiovascular disease or other causes in the short term, a new study suggests. The new study, conducted by researchers at Federico II University in Naples, Italy, involved data from eight previously published trials involving a total of almost 25,000 patients. All were at risk for heart disease but had not had a previous heart attack or stroke. The meta-analysis ... Read More

Dialysis patients seeing nephrologists with larger caseloads at greater risk of dying

Patients receiving dialysis treatments from physicians with greater caseloads are more likely to die than patients of less-busy nephrologists, according to a new study published in the Journal of the American Society of Nephrology. Researchers noted that patients’ death risk increased 2 percent for every increase of 50 patients per nephrologist. The study was the first to examine mortality risk in hemodialysis patients based on physician caseload. The study involved 7,600 adults treated by 341 physicians at select DaVita dialysis facilities who underwent hemodialysis for at least 20 consecutive quarters from July 1, 2001, to June 30, 2006. Follow-up was ... Read More