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high blood sugar 15 articles

Future looks dim for novel class of cholesterol-lowering drugs

Drugs from a novel class designed to lower cholesterol levels and reduce the risk of heart attacks, strokes and cardiovascular death are posting dismal results and may never make it to the market. The drug class, known as CETP inhibitors block a protein that transfers HDL cholesterol to LDL cholesterol, which results in higher HDL – or good cholesterol – and lower LDL – or bad cholesterol – levels. Researchers have been trying for years to develop a successful CETP inhibitor in an effort to take a bite out of the market share of statin drugs, the gold standard for lowering ... Read More

Elevated blood sugar levels increases risk of dementia

Late- to middle-aged people with elevated blood sugar levels, such as those associated with pre-diabetes, are more likely to perform poorly on performance and memory tests and are at greater risk of developing Alzheimer’s disease than people without high blood sugar, a new study has found. The findings aren’t earth shattering. Researchers have already determined that people with type 2 diabetes are at an increased risk of developing dementia and other memory-related health conditions. The study is interesting because it delves into what may be causing that risk. Researchers with the University of Wisconsin-Madison gave memory tests to 150 adults ... Read More

New class of cholesterol drugs raises interest at medical conferences

A new class of cholesterol treatments specifically tasked with lowering LDL, or “bad” cholesterol, generated scores of attention at the American College of Cardiology Scientific Sessions meeting last month. The new class of cholesterol-lowering drugs features inhibitors of protein convertase subtilsin-kexin type 9, also known as PCSK9 inhibitors. The sessions involved presentations on clinical trials showing the effectiveness of Amgen’s evolocumab, Regeneron Pharmaceuticals’ alirocumab, and Pfizer’s bococizumab. The class of drugs was initially designed to treat autosomal dominant hypercholesterolemia, a rare genetic disorder. Its effectiveness at treating that condition led to the development of a new target for cholesterol lowering. ... Read More

Abbott recalls FreeStyle, FreeStyle Flash blood glucose meters

Abbott’s FreeStyle and FreeStyle Flash blood glucose meters are being recalled because when used with the Abbott FreeStyle test strips the meters may produce mistakenly low blood glucose results. Both the FreeStyle and the FreeStyle Flash meters have been in production since 2010. Blood glucose meters are used to measure blood sugar levels in diabetic patients. Those who have the meters affected by this recall should immediately contact Abbott Diabetes Care at 1-888-345-5364 to receive a replacement meter. Consumers who have access to an alternative glucose meter should immediately discontinue using their Freestyle or FreeStyle Flash meter and take the necessary ... Read More

Janssen agrees to pay $5.9 million for concealing Risperdal side effects

Johnson & Johnson unit Janssen Pharmaceuticals agreed to pay $5.9 million to settle a lawsuit brought by Montana’s attorney general alleging the company downplayed or hid Risperdal side effects while marketing the bipolar drug to doctors. “This settlement is not only significant in terms of the amount of money Montana will receive, but also in that it protects our citizens from being prescribed Risperdal based on the types of false statements Janssen previously made to our health care providers,” Attorney General Tim Fox said in a statement issued by his office. Janssen is admitting no wrongdoing. However just four months ... Read More

Cholesterol drug Vascepa hits FDA roadblock while seeking wider indication

The Food and Drug Administration (FDA) has rejected Amarin Corp’s preset testing process that is critical to the company’s plan in seeking a wider usage for its cholesterol-lowering drug Vascepa. Vascepa is a prescription-strength fish-oil pill designed to lower triglyceride levels in patients with high cholesterol. The drug was approved in 2012 for a very small and specific use in patients with unusually high triglycerides. Amarin was hoping to expand usage of the drug to include patients at high risk of coronary heart disease who are also taking statin medications. The first line of defense for treating high cholesterol beyond a ... Read More

Type 2 diabetes drug Victoza may improve vascular health but poses cancer risk

Victoza, a type 2 diabetes treatment that works to regulate glucose, may improve the condition of arteries and possibly protect against heart attack or stroke, a new report shows. However, that benefit will have to be weighed against the drug’s cancer risks. Victoza, also known as liragliutide, is an injection made by Novo Nordisk to treat high blood sugar in type 2 diabetics. Many people may be familiar with the drug’s former spokesperson, celebrity chef Paula Deen, who after accepting the company’s offer to front their drug, admitted she was diagnosed with type 2 diabetes two years prior. She has ... Read More

High blood sugar in diabetics, non-diabetics increases dementia risk

High blood sugar levels – even in people without diabetes – put people at greater risk of dementia, according to a new study published in the New England Journal of Medicine. Dementia is a general term to describe a decline in mental ability that is debilitating enough to impact daily life activities. Alzheimer’s disease is the most common type of dementia. Dementia is a potential complication for people with type 2 diabetes. Other complications of diabetes include cardiovascular disease, amputations due to neuropathy, and blindness. Researchers looked at more than 2,000 Group Health Patients age 65 and older and found ... Read More

Nova diabetes test strips recalled

Several lots of Nova Max Glucose Test Strips used to test blood sugar levels  are being recalled because they may report a false, abnormally high blood glucose result. This defect could, under certain conditions, result in an insulin dosing error that could lead to serious health risks requiring immediate medical attention. The recall, initiated by Nova Diabetes Care, affects 21 lots of Nova Max Glucose Test Strips and Nova Max Plus glucose meter kits that include the test strips. The affected products were distributed both within and outside the continental USA. Nova Diabetes Care has notified all registered users, health ... Read More

Advocates push for more aggressive approach to gestational diabetes

A change in the way pregnant women are tested for gestation diabetes could greatly increase the number of women diagnosed with the disease, which may help keep both mother and baby healthier in the future. Gestational diabetes is a form of the disease that either starts or is first diagnosed during pregnancy. It is a growing problem, as more women are waiting until their 30s or 40s to have babies, and more women are overweight before they become pregnant. It is one of the most common complications of pregnancy. Almost all pregnant women are checked for gestational diabetes because if ... Read More