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increased risk 31 articles

Panel recommends more studies on cardiovascular risks with testosterone drugs

Makers of testosterone replacement drugs should collect data on heart attacks and strokes in men who use their products, and the labels on the treatments should have stronger language to restrict intended uses to reduce over-prescribing, a Food and Drug Administration (FDA) advisory panel recommended. The FDA asked an outside panel of experts to address whether there is a risk of major cardiovascular events such as stroke, heart attack and death in men who used testosterone replacement therapies. The agency also asked the panel whether current evidence still supports the use of the drugs in certain patients. The FDA is ... Read More

FDA says testosterone therapy serves little benefit to men

There is little evidence to show that testosterone replacement products serve any benefit to men, the Food and Drug Administration (FDA) announced this week. Testosterone treatments are prescribed to treat low testosterone levels in men resulting in symptoms such as fatigue, weight gain, muscle loss and low sex drive. Aggressive marketing campaigns from drug companies pushing testosterone products have resulted in skyrocketing prescriptions for testosterone drugs, leading some to wonder how many men are taking the drug who don’t really need it. This is especially worrisome considering two recent studies have linked testosterone supplement use to an increased risk of ... Read More

Pfizer faces thousands of lawsuits linking Lipitor to type 2 diabetes

From the time the cholesterol-lowering statin Lipitor (atorvastatin) hit the market in 1996, it has been the No. 1 best-selling prescription drug in the country, bringing in more than $130 billion in worldwide sales. More than 29 million people in the United States currently take the drug to control their cholesterol. However, this wonder drug comes with a price – an increased risk of type 2 diabetes. Now, thousands of former users have filed lawsuits against drug maker Pfizer alleging the company did not adequately warn users of this risk. In 2012, the Food and Drug Administration (FDA) issued a ... Read More

Young adults who were treated with growth hormones as children may be at greater risk for stroke

People who received growth hormones as children to treat short stature or hormone deficiency should be aware that they are at an increased risk of stroke caused by burst blood vessels when they become young adults, a team of French and British researchers say. The warning is based on findings from a study published in this week’s issue of the journal Neurology, and applies also to people who misuse the growth hormones to improve athletic performance, for body building and other “questionable reasons.” Growth hormones were approved in the United States in the mid-1980s to treat pituitary gland problems and to ... Read More

Healthier diabetics may fare better with less aggressive approach to disease management

Type 2 diabetes drugs could be doing patients more harm than good, especially older diabetics, a new study shows. The research, published in a recent edition of the Journal of the American Medical Association Internal Medicine, addressed how current guidelines for diabetes management were serving patients. Currently, diabetes management involves intensifying treatment until the patient’s blood sugar level has evened out. Researchers say this method appears to cause more negative impacts to patients than positive ones. “For people with type 2 diabetes, the goal of managing blood sugar levels is to prevent associated diabetes complications, such as kidney, eye and ... Read More

New blood clot warnings added to testosterone replacement therapies

Testosterone treatments have been linked to dangerous blood clots in the legs, adding more safety concerns to the hormone supplement currently under review for increasing the risk for strokes, heart attack and death. The Food and Drug Administration (FDA) announced that it was ordering a new warning for deep vein thrombosis be added to the safety labels of testosterone treatments. Deep vein thrombosis is a blood clot that forms in a vein deep in the body. It mainly affects the large veins in the lower leg and thigh. It is a serious condition because blood clots in veins can break ... Read More

FDA approves first-ever nasal testosterone spray

The Food and Drug Administration (FDA) has given clearance for the first-ever nasal testosterone replacement treatment. Natesto Nasal Gel, manufactured by Trimel Pharmaceuticals, is intended for adult males with conditions associated with deficiency or absence of endogenous testosterone, including primary hypogonadism or hypogondotropic hypogondism. Low testosterone levels are associated with symptoms such as low libido, muscle loss, fatigue and weight gain. Natesto is self-administered into the nostrils via a metered-dose pump applicator, which delivers 5.5 mg of testosterone. The recommended dosage is 11 mg, or two pumps (one in each nostril), three times daily. The nasal spray offers a new ... Read More

Study links testosterone therapy to brain damage

Testosterone replacement therapy may cause brain damage in Caucasian men, a new study suggests, adding yet another strike against the increasingly popular hormone treatment. Testosterone treatments are approved to boost levels of the hormone in men experiencing symptoms of so-called Low-T, such as a diminished sex drive, fatigue, weight gain and muscle loss. In recent years, prescriptions for testosterone supplements have skyrocketed in the United States, leading many experts to worry that the drug is being given to men who don’t necessarily need it. In its natural form, testosterone helps protect the brain against free radicals, which can damage brain ... Read More

Men should take steps before going on testosterone replacement therapy

Men who are experiencing symptoms of low testosterone, such as low sex drive, fatigue, weight gain and loss of muscle mass, should take key steps before they begin testosterone replacement therapy, as the treatment has been linked to an increased risk of cardiovascular events and death, doctors warn. The first step is to have a blood test to check their testosterone levels. The test should be performed twice, each time in the morning between 8 a.m. and 10 a.m., in order to confirm the results. If the tests show low testosterone, the next step is to determine the cause. “The ... Read More

Johnson and Johnson faces class action lawsuit over ovarian cancer risk linked to talcum powder

A new class action lawsuit alleges that Johnson & Johnson’s Baby Powder is not safe and puts women who use it in their genital area at risk for ovarian cancer. The lawsuit was filed by Denis Mikhlin and Erin Hoffmann in federal court. “As numerous studies have confirmed, Johnson’s Baby Powder leads to a significant increased risk of ovarian cancer. Women who used talc-based powders to powder their genital area have a 33 percent increased risk of ovarian cancer compared to those women who never used the powders,” the lawsuit states. “Despite the potential catastrophic health consequences, defendants do not ... Read More