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increased risk 31 articles

Beer ingredient could be used to treat diabetes, cancer, inflammation

For the most part, alcohol use is discouraged for people with diabetes. But new research shows that an ingredient in beer can be incorporated into new drugs that could be used to treat conditions such as diabetes, inflammation, and some types of cancer. The flavoring agent hops that gives beer its pungent flavor contains a bitter-tasting chemical compound known as humulones. Isolated humulones and their derivatives have documented health benefits. Researchers discovered the configuration of humulones, which is done through a process known as X-ray crystallography. When this chemical undergoes the brewing process, the molecules are rearranged to contain five ... Read More

New drug reaction warnings placed on SSRI and SNRI antidepressants

Patients who use some types of antidepressants with other serotonergic drugs are at an increased risk for developing a potentially life threatening drug reaction known as serotonin syndrome. The drug labels for several antidepressants in the selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) classes now contain a new warning that the drugs should not be used with other serotonergic drugs (including Triptans, Tricyclic antidepressants, Fentanyl, Lithium, Tramadol, Tryptonphan, Buspirone, and St. John’s Wort) and with drugs that impair metabolism of serotonin (in particular, MAOIs, both those intended to treat psychiatric disorders and also others, such as Linezolid and ... Read More

Pancreatitis precaution added to label of type 2 diabetes drug Byetta

Another type 2 diabetes treatment may be slapped with new warnings by the Food and Drug Administration (FDA). The agency has asked Amylin Pharmaceuticals Inc. to include information about pancreatitis among the “precautions” on the label of its drug Byetta (exenatide) based on a large study. Pancreatitis is an inflammation of the pancreas that requires immediate medical attention and hospitalization during an attack. Symptoms include upper abdominal pain that radiates into the back, swollen and tender abdomen, nausea and vomiting, fever, and increased heart rate. In some cases, the pain with pancreatitis may be debilitating. According to the study, 30 ... Read More

China health officials issue warning about link between diabetes drug Actos and bladder cancer

A year after drug regulators including Health Canada and the U.S. Food and Drug Administration (FDA) warned that the type 2 diabetes drug Actos (pioglitazone) increased the risk of bladder cancer, health officials in China are now following suit. China’s State Food and Drug Administration (SFDA) on Tuesday warned doctors and patients that studies showed Actos put users at greater risk for bladder cancer, especially if they used the drug long term. The SFDA advised patients with bladder cancer to avoid the drug if at all possible, or use it in the smallest dose possible. The agency also asked medical ... Read More

FDA to review heart risks with new type 2 diabetes drug Tresiba

A Food and Drug Administration (FDA) advisory panel is expected to take a hard look at cardiovascular risks when it considers whether to recommend for approval Novo Nordisk’s type 2 diabetes drug Tresiba. The drug would go head-to-head with Sanofi’s best selling Lantus insulin, which generated more than $5 billion in revenue last year. News of the advisory panel’s concerns sent Novo Nordisk’s stock to its lowest point in more than 14 months, down 2.7 percent to 935.50. The drug company is the world’s largest insulin maker, and some analysts say Tresiba sales could generate as much as $9 billion ... Read More

Should you take antidepressants while pregnant?

Feeling depressed when pregnant goes against the ultimate joy society tells us we should feel when carrying a child. But many pregnant women – including some with no prior history of the condition – will get the blues. Deciding whether to take medication to treat the symptoms of depression during pregnancy is a difficult one to face. When women become pregnant, the level of the female hormone progesterone dramatically increases. For some women, it can also increase the level of an enzyme that breaks down serotonin, a neurotransmitter that regulates mood, causing symptoms of depression. Numerous studies have estimated that ... Read More

FDA approves two life-long prescription diet drugs

Two new medications are the first in 13 years to be approved by the Food and Drug Administration (FDA) for long-term weight management. Marketed as Belviq and Qsymia, the prescription drugs are designed to be taken for the rest of a person’s life – along with a healthy lifestyle – for obese and overweight people who have been unsuccessful in getting their weight under control with diet and exercise. More than a third of adults in the United States are obese, and obesity contributes to a number of health conditions including high blood pressure, type 2 diabetes, and high cholesterol. “For ... Read More

Takeda stands behind type 2 diabetes drug Actos despite reports of bladder cancer

Takeda Pharmaceuticals says it is confident in its type 2 diabetes medication Actos despite studies that show the drug puts users at risk for bladder cancer. The drug company issued a statement following a newly published study that backed up bladder cancer risks brought to light in an earlier study. The new study involved data from more than 115,000 people who were treated with diabetes drugs from 1988 to 2009. Overall, 470 people were diagnosed with bladder cancer during about 4 ½ years of follow up. Diabetics treated with Actos had an 83 percent increased risk of bladder cancer than ... Read More

Diabetes may have contributed to Dick Clark’s fatal heart attack

Dick Clark, “America’s oldest living teenager” as he was affectionately called, died Wednesday of a massive heart attack. He was 82. Clark had been admitted to the hospital for an outpatient procedure Tuesday evening, but suffered a heart attack shortly after. Doctors were unable to resuscitate him. The famed TV producer and “New Year’s Rockin’ Eve” host appeared never to age, but the years slowly took their toll on Clark. In 2004, he suffered a serious stroke that impaired his speech. And, in an interview with Larry King, Clark admitted he suffered from type 2 diabetes. “Two-thirds of people who ... Read More

Generic Yaz will include same blood clot warnings

Watson Pharmaceuticals has launched Vestura, a generic version of Bayer’s blockbuster birth control pill Yaz. Like their brand-name counterpart, these pills will also carry a safety announcement on their packaging, warning users that studies suggest the drospirenone-containing pills may put users at greater risk for developing life threatening blood clots. Yaz, as well as the brands Yasmin, Beyaz, Safyral, and other generic varieties, combine the hormones drospirenone and ethinyl estradiol. Yaz and its generic versions had sales of about $510 million last year alone. Watson hopes to take a bite out of those profits. However, just as Watson was vying ... Read More