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internal bleeding 19 articles

FDA questions value of aspirin therapy for heart attack prevention

The Food and Drug Administration (FDA) last week denied a request by German drug maker Bayer AG to change the label on packages of its aspirin to promote the benefits of regular aspirin therapy to ward off first heart attack or stroke in people who have never had cardiovascular problems. Now the agency is questioning whether the treatment carries any value to those with no heart issues and whether taking a daily aspirin may actually put these individuals at risk for potentially serious side effects. Aspirin therapy is often recommended for people with cardiovascular disease because it reduces the clotting ... Read More

Woman dies after surgery to remove Mirena IUD, have tubal ligation

A 40-year-old woman died during a routine medical procedure to remove her Mirena IUD and have a tubal ligation, raising more concerns over the safety of the contraceptive devices. Nicole Lee Stein Caruso underwent surgery in April 2011, but something went terribly wrong. During the operation she sustained a small but accidental laceration to her left internal iliac artery – the main artery of the pelvis. Following surgery she complained of pain, was given pain medication, and fell asleep. During the night Caruso lost two quarts of blood through gradual internal bleeding, which sent her into cardiac arrest. She died ... Read More

SSRIs may increase stroke risk

Taking the most common type of antidepressant can increase the risk of certain types of strokes, according to a study published in the journal Neurology. The new research builds on previous studies that linked use of selective serotonin reuptake inhibitors (SSRIs) to major bleeding, such as gastrointestinal bleeding. SSRIs include brand name drugs Zoloft, Paxil, Lexapro and Prozac. SSRIs are thought to inhibit the clumping together of platelets, which could cause internal bleeding. The new study focused on antidepressant use and stroke. Canadian researchers analyzed 16 studies and found that of the combined 500,000 participants, those taking SSRIs were 51 ... Read More

MDL grows to 78 cases against makers of blood thinner Pradaxa


A multi district litigation (MDL) alleging the blood thinner Pradaxa caused serious and fatal bleeding events has grown to include 78 cases. The lawsuits claim that the drug’s manufacturer, Boehring Ingelheim Pharmaceuticals, failed to warn users of the drug’s risks, including the potential for hemorrhaging, and that there is no antidote available that can reverse the drug’s anticoagulant effects. The U.S. Panel on Multi District Litigation approved last month an Illinois plaintiff’s request for the MDL. U.S. Chief Judge David Herndon was assigned to handle the suits. At that time, the 21 claims were pending in 11 different district courts. ... Read More

VA hospital patients sought for intervention involving blood thinner Pradaxa


VA Hospital patients in the Denver, Colorado, area with a common heart condition who are taking the blood thinner Pradaxa (dabigatran) are eligible to participate in an intervention designed to determine why patients take and don’t take their medications. Atrial fibrillation is a common heart rhythm abnormality. It can cause blood clots, which can lead to stroke. Therefore, patients are treated with the blood thinner warfarin, which requires frequent lab monitoring and dose adjustment. The majority of veterans on warfarin are managed in anti-coagulation clinics staffed by pharmacists who routinely contact patients to remind them to get blood draws, to ... Read More

Lawsuits claim Pradaxa never warned that bleeding side effects may not be reversible

The newly approved blood thinner Pradaxa works faster and requires fewer medical exams and dietary restrictions than the long-used warfarin, but it may result in dangerous and sometimes fatal internal bleeding events. Pradaxa was approved by the Food and Drug Administration (FDA) two years ago to prevent strokes in patients with a common heart condition known as atrial fibrillation. It was the first anticoagulant approved to treat atrial fibrillation patients since warfarin was cleared more than 50 years ago. Pradaxa was an attractive alternative to warfarin because there were fewer interactions and patients didn’t need to be as closely monitored. ... Read More

Worldwide effort aims to raise awareness of atrial fibrillation

Medical and patient organizations from 39 countries around the world are teaming up to educate the public about atrial fibrillation (AF), an under-diagnosed, under-treated and potentially life threatening condition that affects tens of millions of people worldwide. In patients with AF, the upper chambers of the heart, known as the atria, quiver instead of beat effectively. Blood does not get pumped completely out of the heart chambers, and can pool and clot. If these blood clots travel to the brain they can trigger a major and often deadly stroke. The Global AF Patient Charter, organized earlier this year at the ... Read More

New procedure could double success rate of atrial fibrillation

A new method for treating atrial fibrillation could potentially lead to a doubling of the success rate for treatment for the serious heart condition, according to a new study. Atrial fibrillation is a condition in which the upper chambers of the heart beat rapidly and ineffectively, which can cause blood to pool in these chambers. If a blood clot forms, breaks free and travels to the brain, it can cause a stroke. To prevent strokes in patients with atrial fibrillation, blood thinners are generally prescribed. But the medication carries serious risks. Warfarin was approved by the Food and Drug Administration ... Read More

Pradaxa lawsuits may be combined in multi district litigation

Leeta Witt claims the new blood thinner Pradaxa caused her to suffer a cerebral hemorrhage that required two surgeries to resolve. Now, she is waiting to find out if her lawsuit against the manufacturer of the drug will be part of a Multi District Litigation. Witt’s lawsuit is one of about a dozen filed since May in the U.S. District Court for the Southern District of Illinois against Pradaxa’s maker Boehringer Ingelheim. Pradaxa was approved by the Food and Drug Administration (FDA) in 2010 to prevent strokes in patients with a type of irregular heart rhythm known as atrial fibrillation. ... Read More

FDA approves generic versions of blood thinner Plavix

The Food and Drug Administration (FDA) has approved generic versions of the blood thinner Plavix (clopidogrel bisulfate), which is used to reduce the risk of heart attack and stroke in patients who have had a recent heart attack or stroke, or have partial or total blockage of an artery, also known as peripheral artery disease. Clopidogrel has a boxed warning to alert health care professionals and patients that the drug may not work well for those with certain genetic factors that affect how the body metabolizes the drug. Patients can be tested for these genetic factors to ensure that clopidogrel is ... Read More