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internal bleeding 19 articles

AF patients who stop using blood thinners are at greater risk for stroke

When people with atrial fibrillation (AF) stop taking a blood thinner, their risk of having a stroke increases dramatically, according to a new study. People with AF are five times more likely than someone without the condition to suffer a stroke. When someone has AF, the upper chambers of the heart quiver or flutter instead of contracting, which can cause the blood to pool and clot. When these clots travel to the brain, they cause a stroke. Anticoagulants work to prevent strokes in AF patients. Though the medication is lifesaving, there are situations in which patients need to stop taking ... Read More

Pradaxa may not be best blood thinner to use with ablation therapy


The blood thinner Pradaxa (dabigatran) is approved for the prevention of strokes in patients with an abnormal heart rhythm known as atrial fibrillation, but experts say because of the bleeding risk, it may not be the best anticoagulant to use in patients undergoing ablation therapy. Ablation therapy is a procedure used to treat atrial fibrillation. During ablation therapy, a thin wire, or catheter, is positioned inside the heart near the pulmonary veins. Radio energy is applied to the tip of the catheter and is used to cauterize, or abate, the heart tissue around each pulmonary vein. This electrically “disconnects” the ... Read More

NZ coroner investigates deaths with blood thinner Pradaxa


New Zealand drug authorities are investigating cases of stomach and brain bleeds from blood thinners used to treat heart conditions. Authorities say the bleeding rates with the medications seen in the country mirror those in other parts of the world. The investigation is being conducted by Medsafe, New Zealand Medicines and Medical Device Safety Authority, a business unit of the Ministry of Health and the authority responsible for the regulation of medicines and medical devices in New Zealand. The agency says it has received 301 reports associated with serious bleeding events in the past year which are related to the ... Read More

More Pradaxa adverse events reported to FDA


The new blood thinner Pradaxa (dabigatran) continues to rack up more complaints to the Food and Drug Administration (FDA) than any other regularly monitored drug, with 931 incidents reported to the FDA in the first quarter of 2011, and an additional 856 reported in the second quarter. The data on suspect drugs is gathered by the Institute for Safe Medication Practices (ISMP) and its findings released in its quarterly newsletter. ISMP is a nonprofit organization devoted entirely to medication error prevention and safe medication use. The organization is known worldwide as the premier resource for impartial, timely, and accurate medication ... Read More

Weighing the side effects of Pradaxa vs. Warfarin


Pradaxa, the first in a new generation of blood thinners, hit the market in October 2010 with much promise and fanfare. The medication, designed to prevent strokes in patients with a particular type of irregular heartbeat, was the first alternative to warfarin (Coumadin) in nearly 60 years. Roughly 2 million people take blood thinners to prevent blood clots, strokes and heart attacks. Warfarin is the most commonly prescribed blood thinner in its class with tens of millions of prescriptions written for the drug each year. But it has a drawback. Warfarin can cause internal bleeding, thus patients need to be ... Read More

Drug company lowers price of controversial blood thinner Pradaxa

Boehringer Ingelheim has announced it is reducing the cost of its oral blood thinner, Pradaxa (dabigatran etexilate), in the UK by 13 percent, a move that the company hopes will encourage the National Health Service (NHS) to make sure the medicine is available to all eligible patients. Pradaxa was recently approved in the UK for the prevention of strokes and systemic embolism in adult patients with non-valvular atrial fibrillation (AF), a type of abnormal heart rhythm, with one or more risk factors. It was approved in the US in October 2010. Pradaxa is in a class of blood thinners known ... Read More

Health Canada issues stronger warnings for blood thinner Pradaxa

Health regulators in Canada have issued a warning on the new blood thinner Pradaxa, sold in Canada as Pradax. The new safety label will warn that the risk of internal bleeding events may be increased among patients with kidney problems, Health Canada announced earlier this month. Pradax labels now recommend that all patients should have their renal function assessed before starting the drug, and that doctors should assess any changes in renal function for patients while on the medication, especially for patients who are 75 years of age and older. Health Canada also Pradax was not recommended for patients with ... Read More

Aspirin therapy may help reduce risk of cancer, prevent spread of disease

Daily low-dose aspirin therapy may hold even more health benefits than previously thought, according to new studies. A daily dose of aspirin may reduce a person’s chance of developing or dying of cancer, and can prevent tumors from spreading, the studies say. Aspirin therapy is often prescribed for patients who have had or are at risk for heart attack and stroke. It works by interfering with the blood’s clotting action. Clots can form when a fatty deposit in the arteries bursts. When clots lodge in the artery, they can cause a heart attack or stroke. Recent studies have shown that ... Read More

Woman files lawsuit against transvaginal mesh manufacturer

For years, Mary Ann McCloskey didn’t know what was wrong with her. It was as if her internal organs were revolting against her body. She endured pain, internal bleeding, and multiple surgeries. Her quality of life plummeted. It wasn’t until February 2010, that Mary Ann discovered her problem wasn’t a medical mystery, but was likely caused by the transvaginal mesh surgically implanted in her pelvis during a medical procedure she received in 2006. The surgical mesh had eroded into her vaginal wall, causing pain and severe complications. Mary Ann is suing C.R. Bard, manufacturer of the Bard pelvi soft acellular ... Read More