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Invokana side effects 23 articles

Merck, Pfizer seek FDA approval for new diabetes treatment

The Food and Drug Administration (FDA) has accepted three New Drug Applications (NDAs) from Merck and Pfizer Inc., for drugs containing ertugliflozin, a new medication from a class of diabetes drugs known as SGLT2 inhibitors. The three NDAs include an ertugliflozin only treatment, a fixed-dose combination of ertugliflozin and the diabetes drug Januvia (sitagliptin), and a fixed-dose combination of ertugliflozin and the first-line diabetes drug metformin. The FDA is expected to review the medication in December 2017. Additionally, the European Medicines Agency (EMA) has also agreed to review three drug applications containing ertugliflozin. The applications are supported by studies comprised ... Read More

Beasley Allen’s Danielle Ward Mason named to Invokana side effects MDL PSC

Beasley Allen attorney Danielle Ward Mason has been appointed to the Plaintiffs’ Steering Committee (PSC) for consolidated multidistrict litigation (MDL) pending in New Jersey federal court against Johnson & Johnson’s Janssen Pharmaceuticals over claims that the company’s type 2 diabetes drug Invokana causes kidney damage and diabetic ketoacidosis. Those suing Janssen allege that the drug company inadequately tested Invokana and failed to warn doctors or patients of Invokana side effects. The Judicial Panel on Multidistrict Litigation consolidated 55 lawsuits from across the country and appointed U.S. District Judge Brian R. Martinotti to preside over the MDL. An MDL is a ... Read More

Top 5 most dangerous Invokana side effects

The type 2 diabetes drug Invokana hit the market in 2013 with much hype. It was the first drug in a new class of diabetes treatments known as SGLT2 inhibitors. Johnson & Johnson and its unit Janssen Pharmaceuticals, stood to make millions – if not billions – from its novel new diabetes pill. Unlike other diabetes drugs that work through the pancreas or liver, SGLT2 inhibitors are metabolized through the kidneys and lower blood sugar levels by excreting excess sugar through the urine. Invokana, which contains the drug ingredient canagliflozin, proved to be a huge hit and remains a top seller ... Read More

Early clinical trials suggested heart risks with diabetes drug Invokana

In the short time that the type 2 diabetes drug Invokana has been on the market, it has been linked to a number of serious side effects including life threatening ketoacidosis and acute kidney injury. But another deadly side effect may soon be unveiled. Johnson & Johnson’s Janssen Pharmaceuticals is currently conducting five studies investigating the cardiovascular risks associated with of its top-selling drug Invokana. Though no data from the study has been released, red flags have been raised. During clinical trials, 13 patients taking Invokana had a heart attack or stroke, compared to just one on a placebo, during ... Read More

Invokana side effects lawsuits centralized in NJ federal court

The Judicial Panel for Multidistrict Litigation has approved a request to centralize dozens of cases in the U.S. District Court for the District of New Jersey over allegations that the diabetes drug Invokana caused kidney failure and ketoacidosis, a serious condition in which too much acid builds up in the blood. There are currently 29 cases filed in the New Jersey federal court. The order brings the total to 55. The panel expects an additional 44 to be transferred from districts in Minnesota, Illinois, Kentucky, Missouri, Virginia and West Virginia. The lawsuits allege Invokana makers Johnson & Johnson subsidiary Janssen Pharmaceuticals ... Read More

Mobile, Alabama, is diabetes capital of America

Mobile, Ala., has the highest rate of diabetes in the country with nearly 18 percent of adults living with the chronic disease, according to a poll conducted by Gallup and health-being company Healthways. Other cities with high rates of diabetes include Charleston, W.Va., and Corpus Christi, Texas. Bellingham, Wash., and Fort Collins, Colo., had the lowest rates of diabetes. Diabetes can have a severe impact on residents’ financial situations, with average medical expenditures costing about $13,700 annually – about 2.3 times higher than those of someone without the disease. These patients also incur indirect costs such as increased absenteeism and ... Read More

Janssen removes Invokana lawsuits to federal court

More than 100 plaintiffs suing Johnson & Johnson subsidiary Janssen Pharmaceuticals over injuries allegedly caused by its type 2 diabetes drug Invokana have proposed that the claims be consolidated and tried together in a mass tort proceeding in state court, but the drug company said it exercised its rights provided by the Class Action Fairness Act and removed the cases to federal court. The notices were originally filed in early November in the U.S. District Court for the Eastern District of Pennsylvania. Plaintiffs are fighting the removal saying it is un-proper under any standard. In September, plaintiffs filed a petition ... Read More

Proposed class action in Canada targets Invokana side effects

Rosalba Joudry of Nova Scotia took the the type 2 diabetes medication Invokana for eight months but stopped when she saw an advertisement on American TV that linked Invokana to dangerous side effects. Shortly after, her kidneys began to fail. Joudry filed a lawsuit in the Ontario (Canada) Superior Court of Justice, which is now the center of a potential class action lawsuit in that country. The lawsuit seeks more than $1 billion in damages on behalf of Canadian patients who claim to have been harmed by the medication. The lawsuit names Invokana maker, Johnson & Johnson subsidiary Janssen Pharmaceuticals. “We ... Read More

Google recognizes father of insulin therapy on World Diabetes Day

Google is honoring the scientist who discovered that insulin could treat diabetes with a commemorative Doodle on Nov. 14 – World Diabetes Day. Google occasionally temporarily alters its logo – called a Google Doodle – to celebrate holidays, events, achievements and people. Today’s Google Doodle honors Sir Frederick Banting, a Canadian researcher who won the Nobel Prize for his discovery of insulin as a treatment for diabetes. Today would also have been Banting’s 125th birthday. Banting only lived to be 49, but accomplished a lot in that time. He served in World War I, after which he became fascinated with ... Read More

Invokana can increase appetite in some patients, offsetting weight loss

Patients with type 2 diabetes who were treated with Invokana experienced weight loss not due to dieting but simply by the way the drug works. But others taking the drug consumed more calories, researches are expected to report during Obesity Week 2016, an annual meeting of the American Society for Metabolic and Bariatric Surgery and the Obesity Society next month. Invokana, known chemically as canagliflozin, is made by Johnson & Johnson’s Janssen Pharmaceuticals. It is in a class of diabetes drugs known as sodium glucose cotransporter-2 (SGLT2) inhibitors. The drugs were first introduced in 2013. The drug works by allowing the ... Read More