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Invokana 112 articles

FDA approves new type 2 diabetes drug, orders studies on cancer, organ risks

A new type 2 diabetes drug that works differently than all others currently on the market has been approved by the Food and Drug Administration (FDA). Invokana, made by Johnson & Johnson, is a once-a-day medication designed to lower blood sugar by flushing it out in patients’ urine. Analysts believe Invokana could generate $1 billion in annual sales, earning it the coveted “blockbuster drug” status. It is different than other type 2 diabetes medications in that it works by blocking the kidneys from reabsorbing sugar. Older drugs work by reducing the amount of sugar absorbed from food and stored in ... Read More

Experimental diabetes drug tied to heart attacks, strokes, death

An increased risk of heart attacks, strokes and deaths may hurt the chances of Johnson & Johnson’s experimental diabetes drug canagliflozin being approved by the Food and Drug Administration (FDA). Data from nine large patient studies showed the drug raised levels of LDL, or bad cholesterol, and slightly increased risk of cardiovascular events or death compared to two other types of diabetes medications. The drug was also tied to urinary tract infections and fungal infections in the genital area, likely because the drug works by increasing the amount of sugar excreted in the urine, and germs thrive on that sugar. ... Read More