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irritability 20 articles

Risperdal can cause boys to grow breast tissue

When Sabrina Nixon’s son started developing breasts, his pediatrician said it was normal for a boy going through puberty. But at 16, Nixon began to wonder if it was something more serious. A visit with his primary care doctor confirmed her hunch. Her son has gynecomastia, a condition in which boys and men develop breast tissue. Gynecomastia can be embarrassing for boys, causing emotional scars. But it can also be physically painful. Breasts can become tender and even lactate. The condition can impede male reproduction and increase the risk of beast cancer. Gynecomastia typically goes away in time but for ... Read More

Antipsychotic drugs linked to kidney injury in elderly patients

Antipsychotic medications, including risperidone, can cause kidney injury, especially in elderly patients, according to a new study published in the Annals of Internal Medicine. Quetiapine (Seroquel), risperidone (Risperdal), and olanzapine (Zyprexa), are approved by the Food and Drug Administration (FDA) to treat bipolar disorder, schizophrenia and other serious mental disorders. They are also frequently prescribed “off-label” to older adults to treat symptoms such as aggression or agitation associated with Alzheimer’s, dementia, or other neurodegenerative diseases. The study found that older adults taking quetiapine, risperidone or olanzapine were one and a half times more likely to have acute kidney injury compared ... Read More

Medication errors with risperidone still a problem despite warnings, action steps

Despite warnings from the Food and Drug Administration (FDA) and action steps to avoid confusion, the Institute for Safe Medication Practices (ISMP) continues to receive reports of mix-ups between the prescription drugs risperidone (Risperdal) and ropinirole (Requip). Risperidone is an antipsychotic medication used to treat both children and adults with bipolar disorder, schizophrenia and irritability associated with autism. Ropinirole treats symptoms of Parkinson’s disease and restless leg syndrome. In 2011, the FDA alerted the public that the ISMP and FDA had received more than 200 reports of medication errors, some of which resulted in patients being hospitalized. The agency said ... Read More

Plaintiffs ask judge to reconsider ban on punitive damages in Risperdal lawsuits

Plaintiffs suing Johnson & Johnson’s unit Janssen Pharmaceuticals for injuries caused by off-label use of the companies’ antipsychotic drug Risperdal are asking a Pennsylvania judge to reconsider an order that shields the companies from punitive damages. Plaintiffs instead are asking Judge Arnold New with the Philadelphia County Court of Common Pleas to order that punitive damages in the Risperdal mass tort program be made on a case-by-case basis. Judge New ruled in May that the Risperdal mass tort be administered by New Jersey law, which includes a Products Liability Act that bars punitive damages in lawsuits on drugs that are approved ... Read More

Janssen asks judge to set deadline on Risperdal gynecomastia lawsuits

Johnson & Johnson subsidiary Janssen Pharmaceuticals is asking a judge to rule that the statute of limitations has run out for hundreds of lawsuits filed against the company for an embarrassing side effect of its antipsychotic drug Risperdal. The lawsuits are part of a growing mass tort docket alleging Risperdal, also known as risperidone, caused gynecomastia, a condition in which boys and young men grow breasts. The condition can be painful and breasts can lactate. Treatment for gynecomastia often involves surgeries such as liposuction or mastectomy. The Risperdal lawsuits claim the company promoted Risperdal for unapproved uses in adolescent boys while providing inadequate ... Read More

FDA panel votes against approval of Singulair Allergy for OTC use

A Food and Drug Administration (FDA) advisory panel is recommending that the agency not approve Merck’s Singulair Allergy drug for over-the-counter treatment for allergic rhinitis because of safety concerns. Singulair, which contains the active ingredient montelukast, was approved in 1998 for the treatment of asthma in both children and adults. In 2002 and 2005, the indication was expanded to include the treatment for seasonal allergic rhinitis and perennial allergic rhinitis, respectively. In 2007, it was approved for exercise-induced bronchoconstriction. Merck was seeking OTC approval of Singulair Allergy for the treatment of allergy symptoms only in adults 18 years and older, ... Read More

Increasing number of foster care children prescribed antipsychotic drugs like Risperdal for ADHD

More and more children and teenagers in foster care are being prescribed antipsychotic drugs, such as Risperdal, to treat attention-deficit hyperactivity disorder (ADHD), according to a new study published online in the Journal of Child and Adolescent Psychopharmacology. Antipsychotic drugs are not approved by the Food and Drug Administration (FDA) to treat ADHD, though doctors have the authority to prescribe medications for so-called off-label uses. Many of these children and adolescents may not need the medication and by needlessly taking it may be exposed to potentially dangerous Risperdal side effects. The study involved data on more than 260,000 youths aged 2 ... Read More

Boy files Risperdal lawsuit after developing breasts

John was 7 years old when he began taking the antipsychotic drug Risperdal to treat attention deficit disorder, or ADD. Risperdal side effects caused him to be more aggressive, become sleepy and develop bowel problems, his mother said. However, he continued on the drug for several years. Then, at age 14, at the peak of puberty, John began to grow breasts. “It was embarrassing,” his mother confirms. It was a while before they learned John’s breast growth was linked to his Risperdal. They sought legal counsel and have filed a lawsuit against the makers of Risperdal, Johnson & Johnson unit ... Read More

Teenager warns others about humiliating Risperidal side effect

Sam Wilson tried for years to hide the humiliating side effect he developed while taking the antipsychotic drug Risperdal. But now the teenager is ready to speak out in an effort to warn boys taking the drug. Sam was 10 when he was first prescribed Risperdal to treat behavioral problems. He continued on the drug for seven years and during that time he began to grow breasts. Concerned, his mother Pam called the manufacturer of the drug, Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson, and inquired about her son’s condition. A company representative told her that her son’s condition had ... Read More

Risperdal side effects include boys growing breasts

Lawsuits are mounting against Johnson & Johnson subsidiary Janssen Pharmaceuticals for claims that boys who took the anti-psychotic drug Risperdal grew breasts – some as large as D cups. “There is a major design defect here … not just the fact that labeling understated risks,” an attorney for one victim told PharmaLive.com. Risperdal, also known as risperidone, is used to treat adults and children with schizophrenia, bipolar disorder and autism with irritability. The lawsuits allege that Janssen knew that Risperdal could cause boys to develop  gynecomastia, a condition in which the breast tissue develops and grows. However, the lawsuits claim, ... Read More