Tagged Articles

Johnson & Johnson 778 articles

Journal report describes devastating effects of defective artificial hips

The online edition of the Journal of Bone & Joint Surgery has published a case report today entitled Arthroprosthetic Cobaltism: Neurological and Cardiac Manifestations in Two Patients with Metal-on-Metal Arthroplasty. In other words, the article describes the real-life brain-function and heart problems caused by heavy metal poisoning – a common complaint found in patients who receive defective DePuy hip replacements. Perhaps the most interesting aspect of this article is that its author, Dr. Stephen S. Tower of the Anchorage Fracture and Orthopedic Clinic in Anchorage, Alaska, is also one of the two subjects featured in the anthroplasty report. Dr. Tower and the ... Read More

Osteoarthritis drug may work too well, causing patients to overuse joints

Details of a 16-week clinical trial on the osteoarthritis drug tanezumab show the medication offers considerable improvement in the condition of patients with just a few small side effects, according to an article published in a recent issue of the New England Journal of Medicine. Previous studies of the drug were halted while the Food and Drug Administration (FDA) reviewed data that suggested the drug may speed up the progression of osteoarthritis. The agency later determined that the drug worked too well, leading some patients to overuse their joints because they were suddenly pain free, which caused them to damage ... Read More

Medical school to establish database of total joint replacement surgeries

The University of Massachusetts Medical School (UMMS) has received a $12 million grant, with which it intends to begin compiling assessments of key factors related to total joint replacement (TJR) surgery. These surgeries include knee and hip replacement surgeries. The medical school plans to compile a national database that will include more than 33,000 patients who have had total joint replacements and develop tools with which to assess the success and failure of the surgery. Ultimately, they hope the study will help with both research and to guide clinical care and health care policy, according to a release from the ... Read More

DePuy hip replacement recall may affect wide range of patients

It used to be that the average patient for a hip replacement surgery was between 65 and 80 years old. The surgery, first performed in 1960, is a major undertaking, involving one of the body’s largest weight-bearing joints. However, advances in technology and surgical techniques, combined with today’s expectations about continuing strenuous or challenging physical activities later in life, have contributed to a growing population of younger patients. According to a report in the Dallas News, orthopedic surgeons are reporting that it is not unusual for someone as young as 50 to get joint replacement surgery. In fact, statistics indicate ... Read More

Off-label marketing boosts drug company profits

Off-label marketing is an illegal yet commonly employed sales strategy that some big pharmaceutical companies practice to broaden the appeal of a drug and boost sales. One of the most blatant examples of off-label marketing involved Bayer Healthcare’s blockbuster birth control pill Yaz. Bayer promoted the drug as a treatment for premenstrual dysphoric disorder (PMDD) symptoms and to clear up moderate cases of acne when the FDA approved it as birth control only. Bayer stopped the deceptive marketing of Yaz when the FDA cited it for false and misleading advertising. After Bayer was admonished over its Yaz ads, attorneys general ... Read More

Family appeals case against makers of Children’s Motrin

The mother of 11-year-old Sabrina Johnson was clearly agitated when last summer a jury found Johnson & Johnson and McNeil Laboratories not liable for her daughter’s strong adverse reaction to over-the-counter medicine that left her blind. To Sabrina’s mother Joan, who was quoted by ABC 7 Eyewitness News, the ruling sent a painful message: “It means that nobody cares that she has been blinded. It means that nobody cares that she was almost tortured to death. That’s got to matter to somebody. And no, you should not see children, or mothers watching their children die. You’ve got to look into ... Read More

Ortho Evra birth control patch label change

The FDA approved a label change to Johnson & Johnson’s Ortho Evra birth control patch on January 18, 2008. The patch has been known to cause blood clots which can lead to pulmonary embolism and death. The label change comes after testing revealed women on the patch between the ages of 15-44 are at a higher risk for pulmonary embolism. Currently there is litigation pending throughout the United States, including in Chicago, relating to the use of the Ortho Evra patch. Plaintiffs have filed claims after suffering from blood clots, pulmonary embolisms and in some cases death. The side effects ... Read More

J&J pays $1.25m to settle lawuit over death of 14-year-old

Johnson & Johnson agreed to pay $1.25 million to settle a lawsuit over the death of a 14-year-old girl who used the company’s Ortho Evra birth-control patch, according to court records. The confidential agreement involved Alycia Brown, a resident of LaCrosse, Wisconsin, who suffered two blood clots in her lungs on May 7, 2004, after using the patch for several weeks. J&J, the world’s largest maker of health-care products, faces lawsuits by 2,400 of the 5 million women who used the patch. Most claim they suffered strokes or clots in their legs or lungs. The company settled dozens of cases ... Read More