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leukemia 60 articles

Auto worker sues solvent makers over benzene exposure

A former automotive industry worker has filed a federal lawsuit against United States Steel Corporation and two affiliated companies, alleging he was harmed by decades of exposure to solvents containing benzene that he was required to use. Minnesota resident Leonard Samuelson filed his complaint in a Minnesota federal court January 15, alleging that his career as an automotive mechanic and auto hobbyist required him to work with a number of products containing toxic benzene, including Liquid Wrench; Berryman B-12 Chemtool Carburetor, Choke, and Throttle Body Cleaner; and Berryman Brake Parts Cleaner. His exposure to dangerous levels of benzene in the ... Read More

SoCalGas Understated Levels of Toxic Benzene in Massive Gas Leak

Southern California Gas Company (SoCalGas) has been downplaying the number of air pollution tests indicating higher-than-normal levels of benzene spewing from its out-of-control gas leak near Porter Ranch, Calif., the Associated Press reported. The natural gas leak has been billowing metric tons of greenhouse gases since Oct. 23, forcing the relocation of more than 5,000 homes in the Porter Ranch area, about 17 miles northwest of Burbank. The leak is being compared to BP’s Deepwater Horizon oil spill for its magnitude and environmental impact, prompting California Governor Jerry Brown to declare a state of emergency. According to the AP, SoCalGas ... Read More

Study: In-home pesticide usage may cause childhood cancer

According to the children’s health journal Pediatrics, exposure to harmful pesticides may increase a child’s likelihood of developing cancer. Analysts with Pediatrics took an in-depth look at 16 different studies recording children’s reactions to indoor insecticides, outdoor insecticides and herbicides. The studies also included 1,200 children diagnosed with cancer. The most common cancer found in children is childhood leukemia – the most prevalent form of which is acute lymphocytic leukemia. Symptoms of this tragic disease are headaches, weakness, tiredness, feeling cold, pale skin and shortness of breath. Exposure to indoor insecticides caused children to be 47 percent more likely to ... Read More

Many breast cancer patients don’t seek prompt treatment for drug-related heart failure

About 12 percent of breast cancer patients treated with chemotherapy drugs develop heart failure within three years after cancer treatment, but only a third saw a cardiologist within 90 days of the onset of symptoms, according to a new study. The research was presented at the American Cancer Society meeting in Baltimore. The study involved data from about 8,400 breast cancer patients age 65 and older who were treated either with chemotherapy drugs called anthracyclines, or a targeted therapy trastuzumab. Both drugs have been previously linked to heart problems. Researchers said that patients who saw a cardiologist were more likely ... Read More

Ariad Pharmaceuticals adds serious blood clot, heart failure risks to label of leukemia drug

Ariad Pharmaceuticals is re-launching its leukemia drug Iclusig (ponatinib) with new warnings about potential blood clots and the risk of heart failure. The Food and Drug Administration (FDA) ceased sales and promotion of the drug until the drug company addressed safety concerns including the danger of life-threatening blood clots associated with the medication. Iclusig is a treatment for two rare types of leukemia, chronic myeloid leukemia and acute myeloid leukemia. About 5,000 people are diagnosed with the chronic variety of the disease each year. Iclusig was approved by the FDA in late 2012 under the condition that it carry a ... Read More

Genetic mutation associated with cancer more likely in type 2 diabetics

People with a genetic abnormality associated with cancer are more likely to have type 2 diabetes, according to a new study published in the journal Nature Genetics. Type 2 diabetics are already at higher risk of developing cancer, especially blood cancers like lymphoma and leukemia. The new study suggests that gene mutations known as clonal mosaic events, or CMEs, may be source of the problem. CMEs occur when cells have extra copies or missing copies of DNA. They are rarely seen in younger people but are more likely to occur as people age. Previous research has shown that people with ... Read More

Mayflower, Arkansas, residents falling ill after ExxonMobil oil spill

ExxonMobil insists the air in the area just outside the epicenter of its Mayflower, Arkansas, pipeline breach is safe to breathe. Public health advocates, however, warn that even very low levels of fumes from the oil spill can affect populations who are more vulnerable than Exxon’s average oil spill cleanup worker, for whom the air quality tests are set. And indeed a number of elderly people, children, and those with respiratory ailments are becoming ill from the ever-present petrochemical stench that has settled in their town. Huffington Post reports that eight children from a Mayflower elementary school were sent home ... Read More

FDA approves new leukemia drug but requires black box warning

The drug Iclusig (ponatinib) has been approved by the Food and Drug Administration (FDA) to treat two rare types of leukemia, but regulators are requiring that the drug’s label include a black box warning for potentially serious side effects – blood clots and liver toxicity. Iclusig, made by Ariad Pharmaceuticals Inc., was approved for treatment-resistant chronic myeloid leukemia and for patients with acute lymphoblastic leukemia with a type of chromosome abnormality. Experts say that the boxed warnings should not have a harsh effect on the sales of the drug because physicians treating patients with these conditions are familiar with the ... Read More

Leukemia drug linked to rare high blood pressure condition

Sprycel (dasatinib), a type of medication used to treat specific types of leukemia, may cause a rare but serious condition known as pulmonary arterial hypertension (PAH), in which there is abnormally high blood pressure in the arteries of the lungs. The Food and Drug Administration (FDA) alerted doctors and patients that a new warning for the about this risk has been added to the Warnings and Precautions section of the Sprycel drug label. Sprycel is used to treat certain adult patients with Philadelphia chromosome-positive chronic myeloid leukemia (CML) or acute lymphoblastic leukemia (ALL). It works by blocking the action of ... Read More