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FDA issues warning of serious adverse reaction to antidepressants

Several popular medications prescribed to treat depression, including Effexor, Paxil, and Prozac, have issued changes to the “Contradictions and Warnings” sections of their labels to warn of a potentially life-threatening adverse reaction known as Neuroleptic Malignant Syndrome (NMS). NMS is a neurological disorder that presents with muscle rigidity, fever, autonomic instability and cognitive changes such as delirium and associated with elevated levels of the enzyme creatine phosphokinase. Once symptoms appear, the progression of the condition is rapid, reaching peak intensity in as little as three days. Symptoms can last anywhere from eight hours to 40 days. The symptoms of NMS ... Read More