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Lexapro 101 articles

Mental health groups ask FDA to remove black box warning for suicide risk from antidepressants

Mental health experts are petitioning the Food and Drug Administration (FDA) to remove its severest warning involving suicidal thoughts from the safety labels on all antidepressants because the warning has resulted in a 33 percent increase in suicide attempts, and has scared away some patients who may benefit from the medication. In 2004, the FDA placed a black box warning, its most serious kind, on all categories of antidepressants, indicating that there is an increased suicide risk in children and adolescents treated with the drugs. Two years later, the FDA extended the warning to young adults to age 25 and recommended ... Read More

New meta-analysis raises serious questions about SSRI use during pregnancy

There is not enough research to provide a clear guidance on the risks or benefits of antidepressant use during pregnancy, however there are serious concerns regarding the drugs’ affects on newborns that should be addressed, a new meta-analysis has found. The analysis on antidepressant use during and after pregnancy was conducted by U.S. Department of Health and Human Services’ Agency for Healthcare Research and Quality. The study focused on a class of antidepressants known as selective serotonin reuptake inhibitors, or SSRIs, which include the brand names Zoloft, Prozac, Lexapro, Celexa, and Paxil. Researchers reported finding evidence that SSRI use during ... Read More

Celexa, Lexapro birth defects lawsuits returned to state court

Fifteen lawsuits over birth defects in children born to women who took the antidepressants Celexa or Lexapro while pregnant were remanded to state court, a federal judge in Camden, N.J., ruled. Attorneys for the drugs’ maker Forest Laboratories unsuccessfully argued that federal jurisdiction was proper because there were questions about the Food and Drug Administration’s (FDA) labeling of the drugs. Defendants’ claims that Forest Research Institute was fraudulently joined as a defendant were rejected as well. The 15 lawsuits are among 20 that were filed in state courts in New Jersey and removed to federal court by the drug companies. ... Read More

New study suggests SSRI use during pregnancy increases risk of autism spectrum disorders in children

Women using antidepressants known as SSRIs (selective serotonin reuptake inhibitors) during pregnancy may be at higher risk of having children with autism spectrum disorders, according to a new study published in the Journal of Autism and Developmental Disorders. Several studies have raised red flags with the use of SSRIs during pregnancy. SSRIs, which include the brand names Zoloft, Paxil, Lexapro, Celexa and Prozac, have been linked to birth defects such as persistent pulmonary hypertension, heart defects, neural tube defects and malformations. Studies have also suggested that children exposed to SSRIs in utero are more likely to have behavioral problems and ... Read More

Study: Children exposed to SSRIs in utero at greater risk for obesity, type 2 diabetes

Babies born to women who took antidepressants while pregnant are more likely to become obese and develop type 2 diabetes, according to a new study. Obesity and type 2 diabetes in children is already on the rise in the United States and is generally blamed on poor diets and reduced physical activity. However, researchers with McMaster University say that maternal antidepressant use may also be a contributing factor in the pediatric obesity and diabetes epidemic. The study focused on a commonly prescribed type of antidepressant known as selective serotonin reuptake inhibitors, or SSRIs, which include the brand names Prozac, Lexapro, ... Read More

Antidepressant use during pregnancy remains controversial issue

A new study suggesting that there is no increased risk of heart defects in newborns exposed to antidepressants in the first three months of gestation is being criticized by medical experts. “While this is an excellent group of researchers, there are some serious flaws with this study,” says Dr. Adam Urato, maternal-fetal medicine specialist at Tufts Medical Center in Boston. “This isn’t rocket science. We know that exposing developing babies to synthetic chemicals is almost always a really bad idea and should be avoided whenever possible. This study does nothing to alter that common sense concolusion.” The study, conducted by ... Read More

SSRI use in third trimester linked to persistent pulmonary hypertension (PPHN) in newborns

Babies born to women who used SSRI antidepressants during the third trimester of their pregnancies were at an increased risk of giving birth to a baby with persistent pulmonary hypertension in the newborn, or PPHN, according to new research. The study, conducted by researchers with the Sunnybrook Health Sciences Center in Toronto, Canada and the University of Toronto, involved data from seven meta-analyses. Researchers looked at maternal use of SSRIs, or selective serotonin reuptake inhibitors, during different trimesters of pregnancy and the incidence of PPHN. The greatest risk of PPHN was found to be in the third trimester. SSRIs include ... Read More

North Carolina woman says prescription drug-induced psychosis led husband to kill daughters

The moment Kim Crespi of Charlotte, N.C., heard that her husband David had stabbed their 5-year-old twin daughters to death, she knew that the real culprit behind the horrific act wasn’t her spouse but a cocktail of prescription drugs, including Selective Serotonin Reuptake Inhibitors, or SSRIs – a form of antidepressants. According to Charlotte’s WBTV, David Crespi, a Charlotte-area banker, called 911 on the morning of Jan. 20, 2006 to report that he had just killed his own daughters. Mr. Crespi was arrested and ultimately took a plea bargain to avoid the death penalty. He is now serving two life ... Read More

Young people who start antidepressants at higher doses more prone to suicidal thoughts

Children and young adults who start taking antidepressants at higher than recommended doses are twice as likely to have suicidal thoughts or attempt suicide than those who begin treatment at lower doses, according to a new study published in JAMA Internal Medicine. For the study, researchers examined data from 1998 through 2010 on about 163,000 people ages 10 to 64 who were treated for depression. Some people in the study were given the recommended dosage, while others were started at higher doses. It was not made clear why some individuals started at higher-than-typical doses. About 18 percent of 10- to ... Read More

Boys with autism more likely to have been exposed to SSRIs in womb

Boys born to women who took a type of antidepressant during pregnancy were three times more likely to be diagnosed with autism than boys who were not exposed to the drugs in utero, a new study has found. The greatest risk was in boys who were exposed to the drugs during the mother’s first trimester of pregnancy. Researchers also found boys exposed to these antidepressants were more likely to have developmental delays. The new study, published this week online and in the May issue of the journal Pediatrics, focused on a commonly prescribed class of antidepressants known as selective serotonin ... Read More