Tagged Articles

long-term risks 18 articles

Researcher finds ‘profound abnormalities’ in brains of retired NFL players

A researcher studying the long-term risks of combative sports on the brains of retired professional football players said he observed “some of the most profound abnormalities in brain activity that I have ever seen.” Lead author Adam Hampshire, a neuroscientist at Imperial College London, said he saw unusual activity in the frontal lobe of retired National Football League (NFL) players as they performed cognitive tests. “(The) level of brain abnormality correlates strongly with the measure of head impacts of great enough severity to warrant being taken out of play,” he said. “It is highly likely that damage caused by blows ... Read More

Consumer watchdog wants strong warnings placed on blood thinner Plavix

Consumer watchdog group Public Citizen is lobbying federal drug regulators to place a black box warning on the anticoagulant Plavix notifying that patients with drug-delivering coronary artery stents could die from a major bleeding event if they take the medication for more than a year. A black box warning is the strongest warning placed on prescription medication and is given to products that, based on medical studies, pose a serious or life threatening risk for adverse events. More than 25 million prescriptions for Plavix, and its generic equivalent clopidogrel, were written during the past year. The blood thinner is used alone ... Read More

Alabama court rules that makers of brand name drugs can be sued by generic drug users

Generic drugs should carry the same warnings as the brand name drug and, if not, then users of the generic drug can sue the name-brand drug maker for fraudulent misrepresentation, the Alabama Supreme Court ruled. The ruling comes as a response to a certified question from a U.S. District Court, which arose during a case where a plaintiff alleged that a generic version of the prescription heartburn drug Reglan caused him to develop a movement disorder called Tardive Dyskinesia. The plaintiff sued the brand name maker, Wyeth, alleging that the company failed to warn both doctors and patients of the ... Read More

Drug companies spend millions to promote testosterone gels

Drug companies peddling testosterone replacement products have their eyes on older men. Advertisements promoting testosterone gels by firms such as Abbott and Eli Lilly have risen more than 170 percent in the past three years to more than $14 million in 2011, according to advertising tracker Kanter Media. Those efforts have resulted in a 90 percent increase in prescriptions for the hormone during the past five years, which translates to nearly $2 billion in global sales. Baby boomers are the target of these campaigns, which ask men if they suffer from a decrease in libido, weight gain or fatigue. The ... Read More

New diet drug Qsymia now available by prescription

The much anticipated diet drug Qsymia is officially on the market. Qsymia, made by Vivus, is one of two new weight loss drugs approved earlier this year by the Food and Drug Administration (FDA), becoming the first diet pills cleared by the FDA in more than 13 years. Unlike other drugs for weight loss, Qsymia, and new rival Belviq, are considered “life-long” treatments for obesity and should be used along with a diet and exercise program. Though both help users lose weight, they work in entirely different ways. Belviq contains the active ingredient lorcaserin, which works by activating a part ... Read More

Patients with metal hips should be checked by doctor annually

People who have received metal-on-metal hip replacement systems should be checked by a doctor every year for as long as they have the implant to ensure the implant isn’t failing or poisoning their blood, says the UK regulator of medical devices. Metal-on-metal hip implants were introduced a decade ago as a more durable artificial hip. Traditional hip implants are made with plastic or ceramic parts, but several manufacturers began offering all-metal versions. The design turned out to be a major flaw. Most hip implants can last 20 years or more, but the newer metal-on-metal devices were beginning to fail at a ... Read More

Woman injured by recalled metal hip implant hires attorney

Sally Gration was barely 50 in 2006 when she was diagnosed with hip dysplasia and underwent a hip replacement surgery. The surgery went well and Sally began looking forward to a life without pain and disability. Artificial hips can last 20 years or more before they need to be replaced. But four years after surgery, Sally began experiencing excruciating pain in her hip. Around that same time she received word from the hospital where she had the surgery that the metal-on-metal hip implant she received had been recalled by the manufacturer because of safety concerns and high failure rates. Before ... Read More

Corroding metal hip implants may cause DNA damage, medical problems

Corroding debris from failing metal-on-metal artificial hips release Cobalt 2+ ions in surrounding tissue, which cause inflammation and may also do damage to DNA which could result in medical complications including cancer, according to researchers from Imperial College London and Ohio State University. Metal-on-metal hip replacement systems were introduced in the early 2000s as a more durable alternative to traditional ceramic or plastic hip implants. But the devices began failing at higher than expected rates after just five years or less. What surgeons found is that the failures were triggered by inflammation in the tissue surrounding the implant. This inflammation was ... Read More