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Low T 116 articles

Man blames heart attack on Low T therapy

Tracy Garner was intrigued by advertisements for testosterone replacement therapy to boost sex drive and improve muscle mass in men with “Low T.” He asked is doctor about the hormone therapy, and in March 2013, Garner was prescribed Eli Lilly and Co.’s Axiron. A few days later, he had a heart attack. Garner is one of about 6,000 men suing manufacturers of testosterone replacement therapy, alleging the drug companies engaged in aggressive marketing of a prescription drug for off-label use – the treatment of so-called Low T, according to Law360. Testosterone treatments are intended for men with hypogonadism, a condition ... Read More

Doctor says testosterone treatment has heart risks

Days before the a lead attorney in the first bellwether trial alleging cardiovascular risks with the testosterone replacement therapy AndroGel fell ill, resulting in a mistrial, a cardiologist who teaches at Northwestern University testified that he believes testosterone treatments increase the risk of heart attacks in older men, Law360 reported. Dr. Hossein Ardehali appeared as an expert witness in the case of Jeffrey Konrad, a Tennessee man who says he was lured by aggressive advertising by AbbVie and other testosterone treatment manufacturers to try the medication to treat symptoms of so-called Low T, a condition allegedly fabricated by manufacturers of ... Read More

First testosterone lawsuit ends in mistrial

The much-anticipated first bellwether trial against AbbVie Inc. over alleged adverse cardiovascular side effects with its testosterone replacement therapy AndroGel ended in a mistrial this week after the lead plaintiff’s attorney was hospitalized due to an illness, according to Law360. The trial involved the case of Jeffrey Konrad, a Tennessee man who claims in 2010 he was lured to try testosterone therapy after watching advertisements promoting testosterone treatment for the so-called condition, Low T. The ads assured him that AndroGel could improve Low-T symptoms such as low sex drive, weight gain and depressed mood. Konrad asked his doctor to prescribe ... Read More

Former FDA chief testifies at testosterone trial

Former Food and Drug Administration (FDA) Commissioner David Kessler told jurors in the first bellwether trial over alleged testosterone side effects that in his opinion manufacturers of the male hormone overstepped federal regulatory boundaries when they aggressively marketed the treatment directly to consumers without proper testing, according to Law360. Kessler was called as the first witness in the case of Jeffrey Konrad, who claims that he was lured by AbbVie’s ads for the testosterone gel AndroGel for a condition the drug company made up called “Low T.” The ads claimed that Low T could cause low libido, weight gain, muscle ... Read More

First testosterone trial begins

More than 2,000 plaintiffs from around the U.S. will be watching this week as the first testosterone trial gets underway in Chicago, according to the Cook County Record. It is the first of seven cases in the class action singled out as bellwethers. Thousands of plaintiffs filed suit against multiple drug manufacturers of testosterone replacement drugs saying the drugs increased their risk of life-threatening adverse effects including blood clots, stroke and heart attack. As Beasley Allen previously explained, the U.S. Judicial Panel on Multidistrict Litigation established a multidistrict litigation (MDL) for testosterone replacement drugs in 2014 following a Food and ... Read More

Testosterone replacement therapy makers can’t dodge trials

U.S. District Judge Matthew Kennelly dissed almost all the arguments AbbVie and Abbott Laboratories made for a summary judgment before the first of seven bellwether trials involving cardiovascular risks with the testosterone replacement treatment AndroGel begins, Law360 reported. The drug companies face more than 7,000 lawsuits in a sprawling multidistrict litigation (MDL) involving several different manufacturers of testosterone replacement therapies. As the maker of the top selling AndroGel, AbbVie will sit in the hot seat for all seven of the selected bellwethers. The first trial is set to begin in June. Plaintiffs suing AbbVie and other testosterone treatment manufacturers allege ... Read More

direct-to-consumer advertising likely increases testosterone treatment sales

The U.S. and New Zealand are the only countries in the world that allow drug companies to advertise directly to consumers. A new study published in the Journal of the American Medical Association (JAMA) shows just how powerful that opportunity is for Big Pharma. Direct-to-consumer advertising in the U.S. increased substantially from 2009 to 2013. The study focused on the marketing of testosterone replacement therapies, the biggest selling product being AndroGel manufactured by AbbVie. Testosterone therapy is intended for men with hypogonadism, a condition in which the body does not produce enough of the male hormone due to defect or ... Read More

Dangerous blood clots more likely during first six months of testosterone treatment

Men using testosterone replacement therapy have a 63 percent increased risk of developing life threatening blood clots during the first six months of treatment, but this testosterone side effect may have run under the radar in previous studies due to methodological issues, according to a study published in the British Medical Journal. Blood clots that start in the vein are called venous thromboembolism (VTE). The two types of VTE include deep vein thrombosis (DVT), a clot in the deep vein, usually the leg but can be in the arm or other veins; and pulmonary embolism (PE), when a DVT clot ... Read More

Study: Testosterone treatment has no effect on memory, mental function in older men

Testosterone replacement therapy is approved for the treatment of hypogonadism, a condition in which men do not produce enough of the male hormone due to disease, injury or defect. But manufacturers of testosterone treatments have heavily promoted the product to treat symptoms of so-called “Low T,” such as low libido, memory loss, weight gain, muscle loss and mood swings. The marketing strategy worked surprisingly well, resulting in skyrocketing sales of testosterone replacement therapies that eventually raised concerns that the drugs were being prescribed to men who actually didn’t need it, such as older men who naturally see a dip in ... Read More

Study: Testosterone replacement therapy ups blood clot risk as much as 63 percent

Men who use testosterone replacement therapy have a 63 percent increased risk of developing a life-threatening blood clot in a vein, and the risk peaks rapidly during the first six months of use, according to a study led by Dr. Carlos Martinez of the Institute for Epidemiology, Statistics and Informatics in Frankfurt, Germany. Blood clots in the veins, a condition known as venous thromboembolism (VTE), is serious. The clot can travel to the heart and cause a heart attack, to the brain and cause stroke, or to the lungs, a condition known as pulmonary embolism. All of these blood clot-related problems ... Read More