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low testosterone 20 articles

First testosterone trial begins

More than 2,000 plaintiffs from around the U.S. will be watching this week as the first testosterone trial gets underway in Chicago, according to the Cook County Record. It is the first of seven cases in the class action singled out as bellwethers. Thousands of plaintiffs filed suit against multiple drug manufacturers of testosterone replacement drugs saying the drugs increased their risk of life-threatening adverse effects including blood clots, stroke and heart attack. As Beasley Allen previously explained, the U.S. Judicial Panel on Multidistrict Litigation established a multidistrict litigation (MDL) for testosterone replacement drugs in 2014 following a Food and ... Read More

Feds want to limit prescribing of testosterone replacement drugs

The indication for testosterone replacement treatments should be scaled back so that fewer men are prescribed them because the drugs do little to counter the signs of aging, a federal advisory panel announced. The group voted 10-1 to recommend that the prescribing language on testosterone supplements be revised to make it clear that the drugs have not been shown to reverse common symptoms of aging such as low libido, muscle loss, weight gain and fatigue. The new wording would limit the drug only for men who have abnormally low hormone levels due to disease or injury. Testosterone levels typically drop ... Read More

New testosterone treatment in development carries fewer side effects

Testosterone levels in men typically drop as a man ages, but when it drops too low it signals a possible problem. In many cases the drop can be associated with obesity, diabetes and circulatory disease. Low testosterone levels can result in symptoms such as low libido, loss of muscle mass, increased body fat, and depression. Regardless the cause, many doctors prescribe testosterone replacement therapies, such as AndroGel, Axiron and Testim, to treat the condition. However, recent studies have shown that testosterone therapy can increase the risk of heart attack, stroke or death. The drugs can also be expensive, and after ... Read More

Drug company tests new drug to boost testosterone levels in men

A new treatment designed to boost testosterone levels in men, which is not a testosterone replacement therapy, is currently being tested in clinical trials. If data is favorable, the drug could be considered for regulatory approval by the end of the year. Repros Therapeutics’ Androxal is a single isomer of clomiphene citrate, which is widely prescribed under the brand name Clomid to induce ovulation in women. The drug has been used off-label as a treatment of secondary male hypogonadism, a condition of low testosterone. Repros is developing Androxal for men of reproductive age with low testosterone due to secondary hypogonadism. ... Read More

Testosterone levels tend to fluctuate significantly in younger men but remain more constant in older men

Most schools of thought suggest that measuring testosterone levels in men can be tricky because the hormone levels vary from day to day as well as hour to hour. However, a new study finds that only young men experience statistically and clinically significant fluctuations in testosterone levels. Researchers studied records of more than 2,500 men ages 26 to 84 who had their testosterone levels checked at an erectile dysfunction clinic. The men were sorted into five age groups, beginning with 26- to 39-year-olds. Each of those groups were divided into sub-groups depending on the time of day their testosterone was ... Read More

Drug company anticipates launch of new oral testosterone treatment

Clarus Therapeutics, an emerging men’s health specialty pharmaceutical company, filed with the Securities and Exchange Commission (SEC) this week to raise up to $86 million in an initial public offering. The biotech company is preparing for the commercial launch of REXTORO, an oral testosterone replacement therapy for which the company has submitted a New Drug Application with the Food and Drug Administration (FDA). If approved, REXTORO will be the first oral testosterone treatment available in the United States. The drug is intended to boost testosterone levels in men with low testosterone levels, also known as hypogonadism. The term “Low T” ... Read More

Man says his stroke was caused by AndroGel testosterone treatment

Ed Downes’ stroke seemed to come out of nowhere. Ed, who was in his upper 40s at the time, was taking medication for hypertension and attention deficit disorder (ADD), but was otherwise healthy. When he began to lose interest in sex and his energy level plummeted, he, like hundreds of thousands of other men, followed the advice of a drug company’s television commercial and had a “conversation with his doctor” to see if he was suffering from low testosterone, or, as the advertisement called it, “Low T.” Ed was prescribed AndroGel, a testosterone replacement gel, which he took for two years. ... Read More

New questionnaire designed to help identify Low T in men

A new assessment tool may help physicians screen men for low testosterone, according to a new study published in the Journal of Men’s Health. The male androgen deficiency syndrome (MADS) questionnaire, developed by researchers at Icahn School of Medicine in New York, is designed to be a more simplified screening tool to help doctors and patients identify patients at risk for hypogonadism, or low testosterone. The new questionnaire was used on 5,071 men from 44 centers in September 2010 and 2011. Nearly two-fifths of the men were identified as having a testosterone deficiency. These men were also more likely not ... Read More

Study: Low T contributes to more satisfying relationships

Low testosterone levels in men have been blamed for a variety of symptoms – from low sex drive and mood swings to weight gain and muscle loss. But a new study shows that low testosterone has its benefits. It may actually contribute to more romantic and satisfying relationships. “The assumption is generally that high testosterone is good for sexual relationships,” says Robin Edelstein, associate professor of psychology with the University of Michigan. Edelstein and her team set out to put that notion to the test. They surveyed 39 heterosexual couples between the ages of 18 and 39 who were in relationships ... Read More

Doctor raises red flags regarding heart risks with testosterone therapy

Testosterone replacement therapy may sound attractive with ads promising to build muscle mass and boost libido, but Low T therapy may not be all that it’s cracked up to be, warns Dr. Joe Littlejohn, a urologist at Orlando Health. It could be deadly. If you listen to the advertisements from drug companies pushing testosterone products, such as AndroGel, Testim and Axiron, the therapy can help men feel decades younger. Though testosterone levels drop naturally as men age, these supplements can help men turn back the clock. What’s not to love? New research, however, has raised some serious red flags that ... Read More