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metoclopramide 116 articles

Time is running out for victims of Reglan to file lawsuits

Time is running out for people who suspect they have experienced serious side effects from the heartburn drug Reglan (metoclopramide) to file a lawsuit seeking compensation for damages. The Food and Drug Administration (FDA) issued a black box warning on the drug on February 26, 2009. Most states have a two-year statute of limitations on personal injury and wrongful death lawsuits, which in the case of Reglan would begin when the black box warning was issued. The statute of limitations in other states ranges from one to six years. Hundreds of people who have been harmed by Reglan have already ... Read More

Doctor: woman’s ‘essential tremors’ caused by heartburn drug Reglan

Things were bad enough for Melissa.* She suffers from a gastrointestinal disorder that has compromised her lifestyle. But nothing prepared her for the problems she would have from the medication used to treat her condition. “I was just diagnosed with essential tremors from Reglan (metoclopramide),” she posted on the Inspire community billboard. “Great … another thing to deal with.” Essential tremors is a slowly progressive neurological disorder that is most recognized by tremors of the arms during voluntary movements such as eating and writing. Essential tremors may also occur in the head or neck, jaw and voice as well as ... Read More

GERD sufferers sought for study on investigational heartburn treatment

Researchers in Sacramento, Calif., are looking for people who still experience troublesome symptoms of gastroesophageal reflux disease (GERD) even while taking heartburn medication, to participate in a study to evaluate an investigational heartburn treatment. Symptoms of GERD include heartburn, or a burning sensation under the breastbone, burning in the back of the throat due to regurgitation of stomach acid, nausea and vomiting. If left untreated, GERD can result in painful inflammation or ulcers in the esophagus, scar tissue in the esophagus, Barrett’s esophagus, cough and asthma, inflammation and infection in the lungs, inflammation of the throat and larynx, and even ... Read More

Experimental gastroparesis drug to be presented at medical conference

A new medication may soon be available for patients who suffer from advanced gastroparesis, or delayed emptying of the stomach contents. Tranzyme Pharma is presenting data on its experimental drug ulimorelin later this month at the 2010 Joint International Meeting in Neurogastroenterology and Motility in Boston, Mass. The presentation, entitled, “Ulimorelin (ghrelin agonist) effects on daily vomiting due to diabetic gastroparesis,” summarizes the effects of ulimorelin in patients with daily, moderate to severe vomiting. Individuals with severe gastroparesis face frequent hospitalizations and emergency room admissions due to recurrent nausea and vomiting, which are often associated with dehydration, malnutrition and weight ... Read More

Infant reflux: Natural remedies should be tried before medical ones

All babies spit up on occasion. It usually occurs because the sphincter at the top of the stomach is often loose, causing babies to spit milk out of their mouths or noses. In otherwise healthy babies who are growing well, the contents of this spit up is mostly milk and parents shouldn’t worry. But for some babies, the spit up contains stomach acid, which can make the lining of the baby’s esophagus tender, red and swollen. This reflux of acid can also be inhaled into the lungs, irritating the sensitive linings. These babies may respond to the bottle or breast ... Read More

Clinical trial seeks diabetics for new gastroparesis treatment

Diabetics who suffer from nausea, vomiting, bloating, or abdominal discomfort after eating may be eligible to participate in a study for an investigational medication to reduce the symptoms associated with delayed stomach emptying, also known as gastroparesis, a condition many diabetics experience. The study is being conducted at institutes in 37 cities in numerous states across the country. Additional criteria to participate includes being 18 years of age or older and free of cancer for five years. Qualified participants will receive all study-related exams and investigational study medication at no cost. Compensation is also provided. Currently, there are few options ... Read More

Forum discusses side effects of heartburn drug Reglan

Wendy from Oklahoma sought advice from fellow gastroparesis sufferers on Inspire.com’s group forum after her doctor recommended she take Reglan (metoclopramide) to treat symptoms of her condition. Gastropareses causes pain and nausea from slow emptying of the stomach contents. Wendy was concerned, she said, because “I read (Reglan) was the leading prescription cause for tardive dyskinesia,” a debilitating involuntary movement disorder similar to Parkinson’s. The numerous responses tell the same story. “My experience with Reglan was absolutely frightening,” says SoCal. “I developed severe Parkinson’s-like tremors and anxiety. And, I don’t even have a history of anxiety. I stopped the drug ... Read More

Two more lawsuits filed against makers of heartburn drug Reglan

Two more lawsuits have been filed in federal court in New Orleans against the manufacturers of an acid reflux medication that allegedly causes a debilitating involuntary movement disorder known as tardive dyskinesia. Ellen Austin filed a suit against Actavis, Actavis Elizabeth and Watson Pharmaceuticals. Leslie Keeper filed suit against Qualitest Pharmaceuticals. Both lawsuits claim the drug Reglan, also known as the generic metoclopramide, caused them to develop the movement disorder. Reglan is a medication commonly used to treat gastrointestinal conditions such as severe heartburn or acid reflux, and diabetic gastroparesis, a condition in which the stomach takes too long to ... Read More

Drugs that block dopamine receptors can cause Tardive Dyskinesia

An estimated 250,000 to 400,000 people in the United States have Tardive Dyskinesia, a disfiguring and debilitating involuntary movement disorder involving symptoms such as lip smacking, tongue thrusting and protruding, eye blinking and bulging, head jerking, facial grimacing, and puckering and pulsing of the lips. The muscle spasms can become painful and embarrassing and often are permanent. But what is most disturbing is that in many cases, the condition could have been prevented. Tardive Dyskinesia is caused by the long-term use of drugs that block dopamine receptors known as dopamine-receptors antagonists or DRAs. Most of the drugs in this category ... Read More

Using Reglan can make you depressed

You can’t turn on the TV these days without hearing that the heartburn medication Reglan, also known by the generic name metoclopramide, has been linked to the serious involuntary movement disorder, Tardive Dyskinesia. But the drug also carries another serious warning – it can cause depression and suicidal thoughts. Reglan was approved by the Food and Drug Administration (FDA) for the treatment of gastrointestinal conditions such as chronic heartburn, severe acid reflux or GERD, nausea, and gastroparesis. One year ago, after numerous reports of people using Reglan developed the often permanent and debilitating movement disorder, the FDA placed a black ... Read More