Preliminary study data suggest that the antidepressant paroxetine should not be prescribed to pregnant women. GlaxoSmithKline (GSK) late last month notified health care professionals that it was strengthening product label warnings advising against the use of paroxetine (Paxil, Paxil CR) by women who are pregnant. The company cited newly analyzed data from a retrospective epidemiologic study of major congenital malformations in infants, saying that “preliminary results suggest an increase in the risk of congenital malformations associated with the use of paroxetine as compared to other antidepressants.” Changes in the drug’s labeling are being made after consultation with the U.S. Food ... Read More
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