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OxyContin 38 articles

Prescription drug deaths rise for 11th consecutive year

The number of prescription drug-induced deaths rose for the 11th straight year, according to a Centers for Disease Control and Prevention (CDC) analysis. Most of the drug deaths were accidents involving potent painkillers such as OxyContin and Vicodin. “This is a big problem that has gotten much worse quickly,” said CDC Director Dr. Thomas Frieden. Prescription drug deaths continue to rise despite efforts to raise awareness of the risks among doctors and patients. The CDC reported a total of 38,329 drug-overdose fatalities nationwide in 2010. Nearly 60 percent of those deaths involved medicines, most of them prescription drugs. In 2009, the ... Read More

Drug company tests OxyContin on pediatric patients

OxyContin maker Purdue Pharma is testing its potent painkiller on pediatric patients to see how the drug works in children. If the clinical trial meets federal guidelines, the company could receive an extension on its patent. The study is designed to see how OxyContin is absorbed, broken down, and eliminated in children compared to adults, and to see if the medication relieves pain in children as well as it does in adults. Researchers say that just because children are smaller, one shouldn’t assume that giving smaller doses will have the same effect in children as adults. Kids’ organs are still ... Read More

FDA targets makers of unapproved oxycodone

The Food and Drug Administration (FDA) is cracking down on companies who peddle unapproved versions of the powerful painkiller oxycodone. Oxycodone is an opioid that is known by the brand name OxyContin. It is highly addictive and one of the most widely abused drugs in the United States. When used inappropriately, it can be fatal. The FDA says it will take action against all unapproved, single-ingredient, immediate-release products containing oxycodone that are taken orally – including tablets, capsules and oral solutions – and are labeled for human use. OxyContin and generic versions of oxycodone are prescription medications that have been ... Read More

Drug overdose antidote may become available over the counter

For the first time, the Food and Drug Administration (FDA) says it will consider allowing the over-the-counter sale of an overdose antidote as a way of curbing the rising death toll from drug overdoses each year. The FDA along with the Centers of Disease Control and Prevention (CDC) and the Drug Enforcement Agency (DEA) gathered last month to discuss strategies to fight prescription drug abuse and misuse. A key topic was widening the availability of naloxone (Narcan), a nontoxic, non-addictive drug that can reverse the potentially fatal opioid overdose. Some of the most misused prescription opioid painkillers include Oxycontin and Vicodin. ... Read More

Prescription drug overdose and abuse now the leading cause of death in U.S.

Public health experts are warning that an epidemic of pharmaceutical drug injuries has broken out nationwide, likely fueled by the ever-growing number of prescriptions written for the relief of pain and anxiety. According to preliminary data from the U.S. Centers for Disease Control and Prevention, the number of drug deaths exceeded the number of traffic fatalities in the U.S. for the first time in 2009, becoming the leading cause of death in the U.S. At least 37,485 people died from prescription drug injuries in 2009 — 1201 more than the number of people killed in traffic accidents during the same ... Read More

FDA approves new tamper-resistant oxycodone

Oxecta, a new formulation of the potent painkiller oxycodone hydrochloride that resists tampering associated with abuse and misuse, has been approved by the Food and Drug Administration (FDA). Manufactured by Pfizer Inc. and Acura Pharmaceuticals Inc., the new tablet is an immediate-release oxycodone medication that utilizes Aversion Technology, a technology that uses commonly available pharmaceutical ingredients that when tampered with causes the active ingredient to gel to prevent injection or irritate nasal passages to discourage inhalation. “Opioid medications are an important treatment option for patients with moderate to severe pain who are not adequately managed by other pain treatments. However, ... Read More

FDA launches program to help reduce risk of opioid abuse

The Food and Drug Administration (FDA) has launched a new program designed to help cut down on the abuse of long-lasting opioid painkillers, a move that goes against the recommendation of the agency’s advisory panel. Opioids are potent painkillers used to manage pain, but because they also cause a euphoric sensation, they are easily abused and are often subject to criminal diversion. Long-lasting or extended-release versions of opioids are particularly dangerous when abused. Over time, individuals have learned effective ways to tamper with these medications by cutting, chewing, breaking or dissolving them, allowing high levels of the active ingredient to ... Read More

FDA to consider abuse-resistant oxycodone, Remoxy

King Pharmaceuticals Inc., in partnership with Pain Therapeutics Inc., has resubmitted its application to the Food and Drug Administration (FDA) for its painkiller Remoxy, touted by the manufacturer as being an abuse-resistant version of OxyContin. The FDA had previously delayed approval of the drug until it had more proof that Remoxy is less addictive. Remoxy is a treatment for moderate to severe chronic pain and is intended to meet the needs of physicians who prescribe opioid painkillers and want to minimize risks of drug diversion, abuse or accidental patient misuse. The drug is used to treat pain by slowly releasing ... Read More