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Pfizer 165 articles

RA treatment Xeljanz linked to increased risk of pulmonary embolism, death

Patients with rheumatoid arthritis (RA) treated with 10mg twice daily doses of Xeljanz or Xeljanz XR (tofacitinib), were at an increased risk of blood clots in the lungs (pulmonary embolism) and death, according to a safety clinical trial. The Food and Drug Administration (FDA) has not approved this dosage of Xeljanz RA for patients with RA; only for patients with ulcerative colitis. This issue was discovered during a clinical trial Pfizer was required to conduct when the drug was first approved by the FDA in 2016. The trial was designed to evaluate the risk of heart-related events, cancer and infection ... Read More

Hospira recalls opioid antidote

Hospira Inc., a Pfizer company, is recalling two lots of the opioid overdose reversal agent Naloxone Hydrochloride injection because there may be bits of particulate matter embedded and loose on the Carpuject Single-use cartridge syringe plunger. If the drug is administered to a patient, there is a chance the patient could experience a range of adverse events including local irritation, allergic reactions, phlebitis, end-organ granuloma, tissue ischemia, pulmonary emboli, pulmonary dysfunction, pulmonary infarction, and toxicity. To date, Hospira has not received any reports of adverse events related to this issue. The recall affects lots 72680LL and 76510LL of Naloxone Hydrochloride ... Read More

Hospira recalls severe hypertension drug

Hospira Inc., a Pfizer company, is recalling four lots of Labetalol Hydrochloride injection, an intravenous drug used to treat severe hypertension, after discovering cracks on the rim surface of vials covered by the stopper and crimp seal. The recall is being initiated because it poses a threat to patients’ health. Cracked vials could render the drug product non-sterile, which could cause patients to suffer adverse events including fever, chills, sepsis or invasive systemic infections. To date, Hospira has not received any reports of adverse events related to this issue. The recall affects three lots of Labetalol Hydrochloride injection, USP, 100 ... Read More

UK men to get Viagra without prescription

Last week the UK announced that it would make Viagra available over the counter. It is the first country where men will be able to obtain the erectile dysfunction drug without a prescription. Men should be able to purchase Viagra Connect in pharmacies in the spring of 2018. It is hoped that this move will counteract the proliferation of illicit counterfeit ED drugs, which are unregulated and often contain dangerous ingredients. According to Pharmaceutical Processing, the U.K.’s Medicines and Healthcare Regulatory Agency (MHRA) has reclassified Viagra Connect, which comes in a dose of 50mg and in a maximum pack size ... Read More

Alberta bans minors from artificial tanning in melanoma prevention effort

In an attempt to lower rising melanoma rates and protect the health of its citizens, Alberta Health Services has instituted and will be enforcing new regulations that ban minors from using artificial tanning services. “Research has shown that using artificial tanning when you are under 35 dramatically increases your risk for melanoma,” Health Minister Sarah Hoffman says according to The South Peace News. “The changes we’re making will help protect our youth from a disease that affects hundreds of Albertans every year and gives Albertans better information about the risks of artificial tanning.” The new rule takes effect on Jan. 1, ... Read More

Hospira recalls more injectable drugs

Hospira, a Pfizer company, has issued a worldwide recall of one lot of the opioid painkiller Hydromorphone injection and four lots of the blood pressure medication Levophed injectable because the products were manufactured with a damaged sterilizing filter for nitrogen, which may have compromised the sterility of the drugs. If these medications are unsterile and administered to patients, adverse events could result ranging from fever, chills, and malaise to severe adverse evens such as septicemia, bacterial meningitides and wound infection. To date, Hospira has not received any reports of adverse events related to this recall. Hydromorphone Hydrochloride injection is used ... Read More

Hospira recalls staph infection treatment

Hospira Inc., a Pfizer company, is recalling one lot Vancomycin Hydrochloride for injection after glass particles were seen floating in a single vial of the staph infection treatment. In the event the glass particulate is administered to a patient, it may result in phlebitis, end-organ granuloma or micro-embolic effects, or gastrointestinal trauma. To date, Hospira has received no reports of adverse events related to this issue. Vancomycin Hydrochloride is used to treat serious or severe infections caused by susceptible strains of methicillin-resistant staphylococci. It is effective in treating staphylococcal endocarditis, septicemia, bone infections, lower respiratory tract infections, and skin and ... Read More

Pfizer faces falling revenue; Viagra sales decline

Over the past three consecutive quarters, Pfizer’s sales have fallen but Investor’s Business Daily reports that the company says it will wait to see what becomes of Trump’s proposed tax reforms before making any acquisitions. Pfizer reportedly said. “We need to see tax reform or absence of tax reform, then look at business development activities.” Its second-quarter saw sales down another 2 percent, with sales of blockbuster drug Viagra falling 13 percent. As of July 17, according to the United States Judicial Panel on Multidistrict Litigation, there are currently 499 lawsuits consolidated from across the nation into federal multidistrict litigation ... Read More

Sodium chloride injection recalled

ICU Medical Inc., is recalling one lot of sodium chloride injection after a customer reported seeing particulate matter floating in the solution. The matter was found in a single flexible container of the sodium chloride and was identified as stainless steel, according to a Food and Drug Administration (FDA) recall notice. Injection of particulate matter could potentially lead to limited adverse events including allergic reactions, local irritation and inflammation in organs and tissues, or other serious adverse events. The recall affects one lot of 0.9 percent sodium chloride, USP 1000mL, which was manufactured in the U.S. by Hospira, a Pfizer ... Read More

Axiron side effects trial dates set

Two cases among more than 6,000 lawsuits waged against Eli Lilly and Co. over testosterone side effects have been selected by the U.S. District Court for the Northern District of Illinois to serve as bellwether trials in the Testosterone Replacement Therapy Product Liability multidistrict litigation (MDL). U.S. District Judge Matthew K. Kennelly selected the case of Tracy Garner and the case of John Debroka Jr. to serve as bellwethers. Garner claims to have had a heart attack after initiating testosterone therapy with Lilly’s Axiron. Debroka alleges he developed deep vein thrombosis, a blood clot deep in the veins, after taking ... Read More